2-methoxyestradiol has been researched along with 2-methoxyestrone in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (31.25) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hejaz, HA; Leese, MP; Mahon, MF; Newman, SP; Potter, BV; Purohit, A; Reed, MJ | 1 |
| Agoston, GE; Cushman, M; Edsall, AB; Lu, TS; McClanahan, RH; Plum, SM; Song, W; Treston, AM | 1 |
| Cortés-Benítez, F; Dutour, R; Poirier, D; Roy, J | 1 |
| Kennedy, JA | 1 |
| Berg, FD; Kuss, E | 1 |
| Brueggemeier, RW; Singh, U | 1 |
| Berg, D; Kuss, E; Warnecke, HH | 1 |
| Brandon, DD; Kono, S; Lipsett, MB; Loriaux, DL; Merriam, GR | 1 |
| MacLusky, NJ; Merriam, GR; Naftolin, F; Picard, MK | 1 |
| Lippert, TH; Mueck, AO; Seeger, H | 1 |
| Hejaz, HA; Potter, BV; Purohit, A; Reed, MJ; Singh, A | 1 |
| Comninos, A; Day, JM; Leese, MP; Newman, SP; Potter, BV; Purohit, A; Reed, MJ; Solomon, C | 1 |
| FRANDSEN, VA | 1 |
| Breen, T; Matei, D; Perkins, S; Quon, C; Schilder, J; Sidor, C; Sutton, G | 1 |
| Abrams, TA; Blaszkowsky, LS; Chan, JA; Fuchs, CS; Kulke, MH; Meyerhardt, JA; Regan, E; Sidor, C; Zhu, AX | 1 |
| Devoto, L; Henríquez, S; Kohen, P; Muñoz, A; Palomino, WA; Strauss, JF; Veenstra, TD; Xu, X | 1 |
2 trial(s) available for 2-methoxyestradiol and 2-methoxyestrone
| Article | Year |
|---|---|
Activity of 2 methoxyestradiol (Panzem NCD) in advanced, platinum-resistant ovarian cancer and primary peritoneal carcinomatosis: a Hoosier Oncology Group trial.
Topics: 2-Methoxyestradiol; Adult; Aged; Antineoplastic Agents; CA-125 Antigen; Disease-Free Survival; Drug Resistance, Neoplasm; Estradiol; Female; Humans; Hydroxyestrones; Middle Aged; Neoplasm Recurrence, Local; Organoplatinum Compounds; Ovarian Neoplasms; Peritoneal Neoplasms | 2009 |
A prospective phase II study of 2-methoxyestradiol administered in combination with bevacizumab in patients with metastatic carcinoid tumors.
Topics: 2-Methoxyestradiol; Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoid Tumor; Cohort Studies; Estradiol; Female; Gastrointestinal Neoplasms; Humans; Hydroxyestrones; Male; Middle Aged; Neoplasm Staging; Patient Dropouts; Survival Analysis; Tumor Burden; Vascular Endothelial Growth Factor A | 2011 |
14 other study(ies) available for 2-methoxyestradiol and 2-methoxyestrone
| Article | Year |
|---|---|
A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Estradiol; Estrone; Female; Humans; Mice; Molecular Structure; Steryl-Sulfatase; Structure-Activity Relationship; Sulfonic Acids; Transplantation, Heterologous | 2005 |
Synthesis and in vivo antitumor evaluation of 2-methoxyestradiol 3-phosphate, 17-phosphate, and 3,17-diphosphate.
Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Cell Line, Tumor; Drug Screening Assays, Antitumor; Estradiol; Humans; Male; Mice; Mice, Inbred C57BL; Organophosphates; Prodrugs; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2007 |
Targeting cytochrome P450 (CYP) 1B1 with steroid derivatives.
Topics: Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Estrogens; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Structure-Activity Relationship | 2016 |
Effect of catechol oestrogens on extraneuronal metabolism of noradrenaline by rabbit uterine endometrium and myometrium.
Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase Inhibitors; Endometrium; Estradiol; Estrogens, Catechol; Female; Hydroxyestrones; Methylation; Monoamine Oxidase Inhibitors; Myometrium; Norepinephrine; Rabbits; Tritium | 1991 |
Urinary excretion of catecholestrogens, 2-methoxy-estrogens and "classical estrogens" throughout the normal menstrual cycle.
Topics: 2-Methoxyestradiol; Adult; Estradiol; Estrogens; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Menstrual Cycle; Radioimmunoassay; Reference Values | 1991 |
Inhibition of rat liver microsomal estrogen 2-hydroxylase by 2-methoxyestrogens.
Topics: 2-Methoxyestradiol; Animals; Cytochrome P-450 CYP1A1; Estradiol; Estrone; Hydroxyestrones; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Steroid Hydroxylases | 1989 |
Synthesis of immunogenic C-6 derivatives of 2-methoxyestrone and 2-methoxyestradiol-17 beta and characterization of the corresponding antisera.
Topics: 2-Methoxyestradiol; Animals; Cattle; Cross Reactions; Estradiol; Estrogens, Conjugated (USP); Estrone; Hydroxyestrones; Immune Sera; Indicators and Reagents; Rabbits; Radioimmunoassay; Serum Albumin, Bovine | 1982 |
Radioimmunoassay and metabolism of the catechol estrogen 2-hydroxyestradiol.
Topics: 2-Methoxyestradiol; Adult; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Estradiol; Female; Half-Life; Humans; Hydroxyestrones; Male; Metabolic Clearance Rate; Middle Aged; Radioimmunoassay | 1982 |
Comparative properties of the catechol estrogens, I: methylation by catechol-O-methyltransferase and binding to cytosol estrogen receptors.
Topics: 2-Methoxyestradiol; Animals; Binding Sites; Catechol O-Methyltransferase; Cytosol; Estradiol; Estriol; Female; Hydroxyestrones; Hypothalamus; Liver; Methylation; Pituitary Gland; Rats; Receptors, Estrogen; Substrate Specificity; Uterus | 1980 |
Effect of estradiol metabolites on prostacyclin synthesis in human endothelial cell cultures.
Topics: 2-Methoxyestradiol; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Estradiol; Estrone; Humans; Hydroxyestrones | 1999 |
Inhibition of deoxyglucose uptake in MCF-7 breast cancer cells by 2-methoxyestrone and 2-methoxyestrone-3-O-sulfamate.
Topics: 2-Methoxyestradiol; Antineoplastic Agents; Biological Transport, Active; Breast Neoplasms; Deoxyglucose; Estradiol; Estrone; Female; Humans; Hydroxyestrones; Insulin; Kinetics; Paclitaxel; Tumor Cells, Cultured | 2000 |
The effects of 2-substituted oestrogen sulphamates on the growth of prostate and ovarian cancer cells.
Topics: 2-Methoxyestradiol; Apoptosis; Cell Division; Cell Separation; Estradiol; Estrone; Female; Flow Cytometry; G1 Phase; G2 Phase; Humans; Hydroxyestrones; Immunoblotting; Inhibitory Concentration 50; Male; Mitosis; Models, Chemical; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Time Factors; Tumor Cells, Cultured | 2003 |
The demonstration of 2-methoxyoestrone and of 2-methoxyoestradiol in human pregnancy urine.
Topics: 2-Methoxyestradiol; Estradiol; Estradiol Congeners; Estrogens; Hydroxyestrones; Pregnancy | 1959 |
Estrogen metabolites in human corpus luteum physiology: differential effects on angiogenic activity.
Topics: 2-Methoxyestradiol; Biotransformation; Cell Line; Chorionic Gonadotropin; Corpus Luteum; Endothelial Cells; Estradiol; Estrogens; Estrone; Female; Granulosa Cells; Healthy Volunteers; Humans; Hydroxyestrones; Neovascularization, Physiologic; Progesterone; Vascular Endothelial Growth Factor A | 2016 |