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2-methoxyestradiol and 2-hydroxyestradiol

2-methoxyestradiol has been researched along with 2-hydroxyestradiol in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (18.00)	18.7374
1990's	5 (10.00)	18.2507
2000's	26 (52.00)	29.6817
2010's	10 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Davis, DL; Zhang, Z	1
Haag, M; Lottering, ML; Seegers, JC	1
Kennedy, JA	1
Hammond, JM; Spicer, LJ	2
Hammond, JM; Spicer, LJ; Walega, MA	1
Barone, S; Bennett, L; Head, RJ; Panek, D; Stitzel, RE	1
Brandon, DD; Kono, S; Lipsett, MB; Loriaux, DL; Merriam, GR	1
Breuer, H; Köster, G; Schneider, HT	1
MacLusky, NJ; Merriam, GR; Naftolin, F; Picard, MK	1
Adlercreutz, H; Carson, M; Loukovaara, M	1
Dubey, RK; Gillespie, DG; Jackson, EK; Keller, PJ	1
Dubey, RK; Fingerle, J; Gillespie, DG; Jackson, EK; Korzekwa, KR; Rosselli, M; Zacharia, LC	1
Dubey, RK; Imthurn, B; Jackson, EK; Keller, PJ; Rosselli, M	1
Baylis, C; Dubey, RK; Gillespie, DG; Jackson, EK; Xiao, S	1
Dubey, RK; Gillespie, DG; Jackson, EK; Zacharia, LC	3
Chiang, HT; Wu, SN	1
Barchiesi, F; Dubey, RK; Fingerle, J; Gillespie, DG; Jackson, EK; Zacharia, LC	1
Chaube, R; Joy, KP	1
Barchiesi, F; Dubey, RK; Gillespie, DG; Imthurn, B; Jackson, EK; Zacharia, LC	1
Dubey, RK; Jackson, EK; Mi, Z; Zacharia, LC	1
Kiuru, PS; Wähälä, K	1
Baranao, JL; Lattanzi, ML; Mudry, MD; Santos, CB	1
Dubey, RK; Gillespie, DG; Imthurn, B; Jackson, EK; Zacharia, LC	2
AXELROD, LR	1
BREUER, H; KNUPPEN, R; PANGELS, G	1
Azcoitia, I; Garcia-Segura, LM; Picazo, O	1
Barchiesi, F; Dubey, RK; Gillespie, DG; Gogos, JA; Jackson, EK; Karayiorgou, M; Zacharia, LC	1
Guzman, RC; Nandi, S; Rajkumar, L; Talamantes, F; Thordarson, G; Yang, J	1
Allison, SD; Dubey, RK; Fielding, RM; Holland, KM; Jackson, EK; Piché, CA; Zacharia, LC	1
Jackson, EK; Mady, HH; Melhem, MF; Salah, EM; Tofovic, SP	1
Joy, KP; Mishra, A	1
Croxatto, HB; Cuevas, CA; Navarrete-Gómez, PA; Orihuela, PA; Parada-Bustamante, A; Ríos, M; Velasquez, LA; Villalón, MJ	1
Chourasia, TK; Joy, KP	1
Dubey, KR; Jackson, EK; Mi, Z; Rosado, BM; Tofovic, PS	1
Amagai, T; Kuruto, R; Ohura, T; Sakakibara, H; Shimoi, K; Takemura, H; Uchiyama, H	1
Joubert, A; Laurens, J; Lottering, ML; Van Zyl, H	1
Gebre, S; Hill, BJ; Jordan, R; Necessary, S; Schlicker, B	1
Babbs, RK; Corwin, RL; Wojnicki, FH	1
Anderson, S; Beard, DR; Gattone, VH; Komers, R; Lindsley, JN; Oyama, TT; Schutzer, WE	1
Carlsten, H; Gogos, JA; Islander, U; Stubelius, A; Tivesten, A; Wilhelmson, AS	1
Dai, CF; Jobe, SO; Li, HH; Li, XF; Li, Y; Magness, RR; Patankar, MS; Yang, XS; Zhao, YJ; Zheng, J	1
Barchiesi, F; Dubey, RK; Gillespie, DG; Jackson, EK; Rosselli, M; Schaufelberger, SA	1
Dubey, RK; Imesch, P; Leeners, B; Samartzis, EP; Twiehaus, A	1
Buñay, J; Castro, A; Florez, M; Molina, C; Moreno, RD; Orihuela, PA; Parada-Bustamante, A; Valencia, C	1

Reviews

2 review(s) available for 2-methoxyestradiol and 2-hydroxyestradiol

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
C2- and C4-position 17beta-estradiol metabolites and their relation to breast cancer. Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al, 2009, Volume: 33, Issue:3 Topics: 2-Methoxyestradiol; Animals; Breast Neoplasms; Cell Proliferation; Estradiol; Estrogens, Catechol; Humans	2009

Other Studies

48 other study(ies) available for 2-methoxyestradiol and 2-hydroxyestradiol

Article	Year
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Cell-type specific responses in prostaglandin secretion by glandular and stromal cells from pig endometrium treated with catecholestrogens, methoxyestrogens and progesterone. Prostaglandins, 1992, Volume: 44, Issue:1 Topics: 2-Methoxyestradiol; Animals; Endometrium; Estradiol; Estrogens, Catechol; Female; Pregnancy; Progesterone; Prostaglandins; Swine	1992
Effects of 17 beta-estradiol metabolites on cell cycle events in MCF-7 cells. Cancer research, 1992, Nov-01, Volume: 52, Issue:21 Topics: 2-Methoxyestradiol; Breast Neoplasms; Cell Cycle; Cyclic AMP; DNA, Neoplasm; Estradiol; G2 Phase; Humans; Methionine; Mitosis; Molecular Weight; Neoplasm Proteins; Phosphorylation; S Phase; Time Factors; Tumor Cells, Cultured	1992
Effect of catechol oestrogens on extraneuronal metabolism of noradrenaline by rabbit uterine endometrium and myometrium. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:3 Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase Inhibitors; Endometrium; Estradiol; Estrogens, Catechol; Female; Hydroxyestrones; Methylation; Monoamine Oxidase Inhibitors; Myometrium; Norepinephrine; Rabbits; Tritium	1991
Catecholestrogens inhibit proliferation and DNA synthesis of porcine granulosa cells in vitro: comparison with estradiol, 5 alpha-dihydrotestosterone, gonadotropins and catecholamines. Molecular and cellular endocrinology, 1989, Volume: 64, Issue:1 Topics: 2-Methoxyestradiol; Animals; Catecholamines; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Dihydrotestosterone; DNA; Estradiol; Estrogens, Catechol; Female; Follicle Stimulating Hormone; Gonadotropins; Granulosa Cells; Swine	1989
Comparative effects of androgens and catecholestrogens on progesterone production by porcine granulosa cells. Molecular and cellular endocrinology, 1988, Volume: 56, Issue:3 Topics: 2-Methoxyestradiol; Androstenedione; Animals; Cell Count; Cells, Cultured; Dihydrotestosterone; Dose-Response Relationship, Drug; Estradiol; Estrogens, Catechol; Female; Flutamide; Follicle Stimulating Hormone; Granulosa Cells; Ovum; Progesterone; Swine; Testosterone	1988
Metabolism of [3H]2-hydroxyestradiol by cultured porcine granulosa cells: evidence for the presence of a catechol-O-methyltransferase pathway and a direct stimulatory effect of 2-methoxyestradiol on progesterone production. Biology of reproduction, 1987, Volume: 36, Issue:3 Topics: 2-Methoxyestradiol; Animals; Ascorbic Acid; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Female; Granulosa Cells; Progesterone; Propiophenones; Swine	1987
The influence of oestrogen and oestrogen metabolites on the sensitivity of the isolated rabbit aorta to catecholamines. Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 335, Issue:5 Topics: 2-Methoxyestradiol; Animals; Aorta, Thoracic; Catechol O-Methyltransferase Inhibitors; Catecholamines; Epinephrine; Estradiol; Estrogens; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Propiophenones; Rabbits	1987
Radioimmunoassay and metabolism of the catechol estrogen 2-hydroxyestradiol. The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:1 Topics: 2-Methoxyestradiol; Adult; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Estradiol; Female; Half-Life; Humans; Hydroxyestrones; Male; Metabolic Clearance Rate; Middle Aged; Radioimmunoassay	1982
Effect of 2-substituted oestrogens in vivo on the metabolism of noradrenaline in rat brain. Acta endocrinologica, 1982, Volume: 99, Issue:1 Topics: 2-Methoxyestradiol; Animals; Brain; Castration; Estradiol; Female; Luteinizing Hormone; Methylation; Norepinephrine; Rats; Rats, Inbred Strains	1982
Comparative properties of the catechol estrogens, I: methylation by catechol-O-methyltransferase and binding to cytosol estrogen receptors. Steroids, 1980, Volume: 36, Issue:1 Topics: 2-Methoxyestradiol; Animals; Binding Sites; Catechol O-Methyltransferase; Cytosol; Estradiol; Estriol; Female; Hydroxyestrones; Hypothalamus; Liver; Methylation; Pituitary Gland; Rats; Receptors, Estrogen; Substrate Specificity; Uterus	1980
Regulation of sex-hormone-binding globulin production by endogenous estrogens in vitro. Biochemical and biophysical research communications, 1995, Jan-26, Volume: 206, Issue:3 Topics: 2-Methoxyestradiol; Carcinoma, Hepatocellular; Estradiol; Estriol; Estrogens; Estrone; Humans; Hydroxyestrones; Liver Neoplasms; Receptors, Estrogen; RNA, Messenger; Sex Hormone-Binding Globulin; Tumor Cells, Cultured	1995
17Beta-estradiol, its metabolites, and progesterone inhibit cardiac fibroblast growth. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2 Topics: 2-Methoxyestradiol; Animals; Cell Division; Cells, Cultured; Collagen; DNA; Estradiol; Estrogen Antagonists; Estrogens, Catechol; Female; Fibroblasts; Humans; Kinetics; Male; Myocardium; Progesterone; Proline; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Sex Characteristics; Tamoxifen	1998
Methoxyestradiols mediate the antimitogenic effects of estradiol on vascular smooth muscle cells via estrogen receptor-independent mechanisms. Biochemical and biophysical research communications, 2000, Nov-11, Volume: 278, Issue:1 Topics: 2-Methoxyestradiol; Animals; Aorta; Aorta, Thoracic; Catechol O-Methyltransferase; Cell Count; Cell Division; Cell Line; Cells, Cultured; Cytochrome P-450 Enzyme System; Cytosol; DNA; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Flavonoids; Fulvestrant; Humans; Inhibitory Concentration 50; Luteolin; Male; MAP Kinase Signaling System; Models, Biological; Muscle, Smooth, Vascular; Protein Binding; Quercetin; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Sex Factors; Time Factors; Tumor Cells, Cultured	2000
Estradiol metabolites inhibit endothelin synthesis by an estrogen receptor-independent mechanism. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2 Topics: 2-Methoxyestradiol; Animals; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, Drug; Endothelins; Estradiol; Estrogen Receptor beta; Female; Fulvestrant; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Receptors, Estrogen; Swine; Time Factors	2001
Effects of estradiol and its metabolites on glomerular endothelial nitric oxide synthesis and mesangial cell growth. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2 Topics: 2-Methoxyestradiol; Cell Division; Cells, Cultured; Endothelium, Vascular; Estradiol; Fulvestrant; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Humans; Kidney Glomerulus; Nitric Oxide; Nitric Oxide Synthase; Progestins; Receptors, Estrogen	2001
Increased 2-methoxyestradiol production in human coronary versus aortic vascular cells. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2 Topics: 2-Methoxyestradiol; Animals; Aorta, Thoracic; Cell Division; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Epinephrine; Estradiol; Female; Humans; Isoproterenol; Kinetics; Methyltransferases; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Sprague-Dawley	2001
Inhibition of large-conductance calcium-activated potassium channel by 2-methoxyestradiol in cultured vascular endothelial (HUV-EC-C) cells. The Journal of membrane biology, 2001, Aug-01, Volume: 182, Issue:3 Topics: 2-Methoxyestradiol; 8-Bromo Cyclic Adenosine Monophosphate; Cell Line; Diazoxide; Drug Interactions; Endothelium, Vascular; Estradiol; Estriol; Evans Blue; Humans; Indoles; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Niflumic Acid; Patch-Clamp Techniques; Peptides; Potassium; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Vasodilator Agents	2001
Catecholamines abrogate antimitogenic effects of 2-hydroxyestradiol on human aortic vascular smooth muscle cells. Arteriosclerosis, thrombosis, and vascular biology, 2001, Volume: 21, Issue:11 Topics: 2-Methoxyestradiol; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aorta; Cell Division; Cell Movement; Cells, Cultured; Collagen; DNA; Drug Antagonism; Epinephrine; Estradiol; Female; Humans; Isoproterenol; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Propranolol	2001
Catecholamines block 2-hydroxyestradiol-induced antimitogenesis in mesangial cells. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:4 Topics: 2-Methoxyestradiol; Animals; Catecholamines; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Glomerular Mesangium; Growth Inhibitors; Kinetics; Proline; Rats; Rats, Sprague-Dawley; Thymidine	2002
Methoxyestradiols mediate estradiol-induced antimitogenesis in human aortic SMCs. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 39, Issue:4 Topics: 2-Methoxyestradiol; Aorta; Catechol O-Methyltransferase Inhibitors; Cell Division; Cell Movement; Cells, Cultured; Collagen; Cytochrome P-450 Enzyme Inhibitors; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Female; Growth Inhibitors; Humans; Muscle, Smooth, Vascular; Receptors, Estrogen	2002
In vitro effects of catecholamines and catecholestrogens on brain tyrosine hydroxylase activity and kinetics in the female catfish Heteropneustes fossilis. Journal of neuroendocrinology, 2003, Volume: 15, Issue:3 Topics: 2-Methoxyestradiol; Animals; Catecholamines; Catfishes; Dopamine; Enzyme Activation; Epinephrine; Estradiol; Estrogens, Catechol; Female; Hypothalamus; In Vitro Techniques; Kinetics; Norepinephrine; Telencephalon; Tyrosine 3-Monooxygenase	2003
CYP450- and COMT-derived estradiol metabolites inhibit activity of human coronary artery SMCs. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:3 Pt 2 Topics: 2-Methoxyestradiol; Aryl Hydrocarbon Hydroxylases; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cell Division; Cell Movement; Cells, Cultured; Collagen; Coronary Vessels; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Estradiol; Female; Humans; Muscle, Smooth, Vascular	2003
Methylation of 2-hydroxyestradiol in isolated organs. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:1 Topics: 2-Methoxyestradiol; Animals; Epinephrine; Estradiol; Female; Kidney; Kinetics; Male; Mesenteric Arteries; Methylation; Myocardium; Norepinephrine; Organ Culture Techniques; Rats; Rats, Sprague-Dawley	2003
Short synthesis of 2-methoxyestradiol and 2-hydroxyestradiol. Steroids, 2003, Volume: 68, Issue:4 Topics: 2-Methoxyestradiol; Estradiol; Hydroxylation; Methylation	2003
Exposure of bovine oocytes to the endogenous metabolite 2-methoxyestradiol during in vitro maturation inhibits early embryonic development. Biology of reproduction, 2003, Volume: 69, Issue:6 Topics: 2-Methoxyestradiol; Animals; Antioxidants; Apoptosis; Blastocyst; Cattle; Cells, Cultured; Colchicine; Cytogenetic Analysis; Dose-Response Relationship, Drug; Estradiol; Estrogens, Catechol; Female; Fertilization in Vitro; Male; Meiosis; Oocytes; Spindle Apparatus	2003
Catecholamines block the antimitogenic effect of estradiol on human glomerular mesangial cells. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:3 Topics: 2-Methoxyestradiol; Aryl Hydrocarbon Hydroxylases; Blotting, Western; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catecholamines; Catechols; Cell Division; Cells, Cultured; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Drug Interactions; Epinephrine; Estradiol; Female; Glomerular Mesangium; Humans; Isoproterenol; Norepinephrine; Phentolamine; Propranolol	2003
In vitro transmethylation of 2-hydroxyestradiol-17 beta to 2-methoxyestradiol-17 alpha-2-methyl-C14. Archives of biochemistry and biophysics, 1960, Volume: 91 Topics: 2-Methoxyestradiol; Estradiol; In Vitro Techniques	1960
[Metabolism of 2-hydroxyestradiol-(17 beta) and 2-methoxyestradiol-(17 beta)in human and rat tissues]. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1961, May-30, Volume: 324 Topics: 2-Methoxyestradiol; Animals; Estradiol; Humans; Rats	1961
Neuroprotective and neurotoxic effects of estrogens. Brain research, 2003, Nov-14, Volume: 990, Issue:1-2 Topics: 2-Methoxyestradiol; Animals; Cell Count; Dentate Gyrus; Estradiol; Estrogens; Excitatory Amino Acid Agonists; Female; Kainic Acid; Neurons; Neuroprotective Agents; Neurotoxins; Ovariectomy; Rats; Rats, Wistar	2003
Methoxyestradiols mediate the antimitogenic effects of 17beta-estradiol: direct evidence from catechol-O-methyltransferase-knockout mice. Circulation, 2003, Dec-16, Volume: 108, Issue:24 Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase; Cell Division; Cells, Cultured; Estradiol; Growth Inhibitors; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular	2003
Prevention of mammary carcinogenesis by short-term estrogen and progestin treatments. Breast cancer research : BCR, 2004, Volume: 6, Issue:1 Topics: 2-Methoxyestradiol; Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Estradiol; Estriol; Estrogens; Ethinyl Estradiol; Female; Mammary Neoplasms, Animal; Megestrol Acetate; Methylnitrosourea; Norethindrone; Progesterone; Progestins; Rats; Rats, Inbred Lew; Tamoxifen; Time Factors; Treatment Outcome	2004
2-hydroxyestradiol is a prodrug of 2-methoxyestradiol. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:3 Topics: 2-Methoxyestradiol; Animals; Dose-Response Relationship, Drug; Estradiol; Male; Prodrugs; Rats; Rats, Sprague-Dawley	2004
Catecholamines block the antimitogenic effect of estradiol on human coronary artery smooth muscle cells. The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:8 Topics: 2-Methoxyestradiol; Aryl Hydrocarbon Hydroxylases; Catechols; Cell Division; Cells, Cultured; Coronary Vessels; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Epinephrine; Estradiol; Estrogen Antagonists; Female; Humans; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Norepinephrine; Phosphorylation	2004
Estradiol metabolites attenuate monocrotaline-induced pulmonary hypertension in rats. Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:4 Topics: 2-Methoxyestradiol; Animals; Blood Pressure; Body Weight; Cell Proliferation; Disease Progression; Estradiol; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Lung; Male; Monocrotaline; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Time Factors; Tubulin Modulators	2005
Relative effects of estradiol-17beta (E2), catecholestrogens and clomiphene citrate on in vitro oocyte maturation in the catfish Heteropneustes fossilis (Bloch) and E2 inhibition of 2-hydroxyestradiol-induced maturation. General and comparative endocrinology, 2006, Volume: 147, Issue:2 Topics: 2-Methoxyestradiol; Animals; Catfishes; Clomiphene; Dose-Response Relationship, Drug; Estradiol; Estrogens, Catechol; Female; In Vitro Techniques; Oocytes; Ovarian Follicle; Time Factors	2006
Catechol-o-methyltransferase and methoxyestradiols participate in the intraoviductal nongenomic pathway through which estradiol accelerates egg transport in cycling rats. Biology of reproduction, 2007, Volume: 77, Issue:6 Topics: 2-Methoxyestradiol; Animals; Aryl Hydrocarbon Hydroxylases; Catechol O-Methyltransferase; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Egg Proteins; Estradiol; Estrogens, Catechol; Female; Gene Expression Regulation; Menstrual Cycle; Methylation; Oviducts; Ovum; Phosphorylation; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Sexual Behavior, Animal	2007
Ovarian P450 aromatase activity in the catfish Heteropneustes fossilis: seasonal changes and effects of catecholestrogens. General and comparative endocrinology, 2008, May-01, Volume: 156, Issue:3 Topics: 2-Methoxyestradiol; Acclimatization; Animals; Aromatase; Aromatase Inhibitors; Catfishes; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrogens; Estrogens, Catechol; Fadrozole; Female; Gonadal Steroid Hormones; Indicators and Reagents; Kinetics; Microsomes; Ovary; Seasons; Vitelline Membrane	2008
Effects of estradiol metabolites on cAMP production and degradation. Prilozi, 2009, Volume: 30, Issue:1 Topics: 2-Methoxyestradiol; Animals; Cells, Cultured; Cyclic AMP; Estradiol; Kidney Glomerulus; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Rats; Rats, Inbred SHR	2009
A methoxyflavonoid, chrysoeriol, selectively inhibits the formation of a carcinogenic estrogen metabolite in MCF-7 breast cancer cells. The Journal of steroid biochemistry and molecular biology, 2010, Volume: 118, Issue:1-2 Topics: 2-Methoxyestradiol; Aryl Hydrocarbon Hydroxylases; Biocatalysis; Breast Neoplasms; Carcinogens; Catechol O-Methyltransferase; Cell Line, Tumor; Chemoprevention; Culture Media, Conditioned; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Inhibitors; Estradiol; Estrogens, Catechol; Female; Flavones; Flavonoids; Gene Expression; Glucuronidase; Humans; Hydroxylation; Kinetics; Methylation; Oxazines; Recombinant Proteins; Sulfatases	2010
Nongenomic inhibition of coronary constriction by 17ß-estradiol, 2-hydroxyestradiol, and 2-methoxyestradiol. Canadian journal of physiology and pharmacology, 2010, Volume: 88, Issue:2 Topics: 2-Methoxyestradiol; Animals; Calcium; Cardiotonic Agents; Coronary Vessels; Drug Therapy, Combination; Endothelium, Vascular; Estradiol; Extracellular Fluid; Female; Genome; Organ Culture Techniques; Swine; Vasoconstriction; Vasodilation	2010
Effect of 2-hydroxyestradiol on binge intake in rats. Physiology & behavior, 2011, Jul-06, Volume: 103, Issue:5 Topics: 2-Methoxyestradiol; Animals; Binge-Eating Disorder; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Eating; Estradiol; Female; Male; Rats; Rats, Sprague-Dawley; Sex Characteristics	2011
2-Hydroxyestradiol slows progression of experimental polycystic kidney disease. American journal of physiology. Renal physiology, 2012, Mar-01, Volume: 302, Issue:5 Topics: 2-Methoxyestradiol; Animals; Apoptosis; Cell Proliferation; Disease Progression; Estradiol; Kidney; Male; Orchiectomy; Polycystic Kidney Diseases; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; TOR Serine-Threonine Kinases; Treatment Outcome	2012
Sexual dimorphisms in the immune system of catechol-O-methyltransferase knockout mice. Immunobiology, 2012, Volume: 217, Issue:8 Topics: 2-Methoxyestradiol; Animals; B-Lymphocytes; Catechol O-Methyltransferase; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Immune System; Immunoglobulins; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Neutrophils; Organ Size; Sex Factors; Single-Cell Analysis; Spleen; T-Lymphocytes; Uterus	2012
Estradiol 17β and its metabolites stimulate cell proliferation and antagonize ascorbic acid-suppressed cell proliferation in human ovarian cancer cells. Reproductive sciences (Thousand Oaks, Calif.), 2014, Volume: 21, Issue:1 Topics: 2-Methoxyestradiol; Aryl Hydrocarbon Hydroxylases; Ascorbic Acid; Catechol O-Methyltransferase; Cell Line, Tumor; Cell Proliferation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens, Catechol; Female; Humans; Ovarian Neoplasms; Time Factors	2014
2-Methoxyestradiol, an endogenous 17β-estradiol metabolite, inhibits microglial proliferation and activation via an estrogen receptor-independent mechanism. American journal of physiology. Endocrinology and metabolism, 2016, Mar-01, Volume: 310, Issue:5 Topics: 2-Methoxyestradiol; Animals; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Cell Proliferation; Cytochrome P-450 Enzyme Inhibitors; DNA; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Mice; Microglia; Phagocytosis; Tubulin Modulators	2016
The estrogen metabolites 2-methoxyestradiol and 2-hydroxyestradiol inhibit endometriotic cell proliferation in estrogen-receptor-independent manner. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2016, Volume: 32, Issue:7 Topics: 2-Methoxyestradiol; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Endometriosis; Estradiol; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans	2016
2-hydroxyoestradiol and 2-methoxyoestradiol, two endogenous oestradiol metabolites, induce DNA fragmentation in Sertoli cells. Andrologia, 2016, Volume: 48, Issue:10 Topics: 2-Methoxyestradiol; Animals; Apoptosis; Caspase 3; Cell Line; Cell Survival; Child; DNA Fragmentation; Estradiol; Estrogen Receptor Antagonists; Fulvestrant; Humans; Male; Mice; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Sertoli Cells	2016