Compounds > 2-methoxyestradiol
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2-methoxyestradiol and 2-ethoxyestradiol

2-methoxyestradiol has been researched along with 2-ethoxyestradiol in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cushman, M; Hamel, E; He, HM; Katzenellenbogen, JA; Lin, CM1
Cushman, M; Hamel, E; He, HM; Katzenellenbogen, JA; Lin, CM; Ram, S; Sachdeva, YP; Varma, RK1
Cushman, M; Fanwick, PE; Hamel, E; Mohanakrishnan, AK; Nampoothiri, P; Wang, Z; Yang, D1
Agoston, GE; Cushman, M; Edsall, AB; Fanwick, PE; Hamel, E; Hanson, AD; Mohanakrishnan, AK; Yang, D1

Other Studies

4 other study(ies) available for 2-methoxyestradiol and 2-ethoxyestradiol

ArticleYear
Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site.
    Journal of medicinal chemistry, 1995, Jun-09, Volume: 38, Issue:12

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Binding Sites; Biopolymers; Cattle; Cell Line; Colchicine; Estradiol; Mitosis; Rats; Receptors, Estrogen; Tubulin Modulators; Tumor Cells, Cultured

1995
Synthesis of analogs of 2-methoxyestradiol with enhanced inhibitory effects on tubulin polymerization and cancer cell growth.
    Journal of medicinal chemistry, 1997, Jul-18, Volume: 40, Issue:15

    Topics: 2-Methoxyestradiol; Animals; Biopolymers; Brain; Cattle; Cell Division; Estradiol; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Rats; Receptors, Estrogen; Spectrophotometry, Infrared; Structure-Activity Relationship; Tubulin; Tubulin Modulators; Tumor Cells, Cultured

1997
Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability.
    Journal of medicinal chemistry, 2000, Jun-15, Volume: 43, Issue:12

    Topics: Animals; Antineoplastic Agents; Cattle; Drug Screening Assays, Antitumor; Estradiol; Humans; Microtubules; Paclitaxel; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured

2000
Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization.
    Journal of medicinal chemistry, 2004, Oct-07, Volume: 47, Issue:21

    Topics: 2-Methoxyestradiol; Antineoplastic Agents; Biopolymers; Cell Division; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Estradiol; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Tubulin

2004