2-mercaptonicotinic-acid has been researched along with alpha-cyclodextrin* in 1 studies
1 other study(ies) available for 2-mercaptonicotinic-acid and alpha-cyclodextrin
Article | Year |
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Mucoadhesive S-protected thiolated cyclodextrin-iodine complexes: a promising strategy to prolong mucosal residence time of iodine.
The purpose of this study was to develop S-protected thiolated α-cyclodextrin-iodine complexes providing prolonged mucosal residence time and sustained release of the antimicrobial agent.. First, L-cysteine was conjugated with 2-mercaptonicotinic acid to generate cysteine-2-mercaptonicotinic acid (Cys-MNA). Subsequently, α-CD was oxidized with NaIO. According to these results, S-protected thiolated α-CD-iodine complex might be a promising novel formulation for the mucosal use of iodine. Topics: Adsorption; alpha-Cyclodextrins; Animals; Anti-Bacterial Agents; Caco-2 Cells; Escherichia coli; Humans; Intestinal Mucosa; Iodine; Kinetics; Molecular Structure; Nicotinic Acids; Oxidation-Reduction; Staphylococcus aureus; Sulfhydryl Compounds; Swine | 2019 |