2-ketodoxapram has been researched along with doxapram in 6 studies
*Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225) [MeSH]
*Doxapram: A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225) [MeSH]
| Studies (2-ketodoxapram) | Trials (2-ketodoxapram) | Recent Studies (post-2010) (2-ketodoxapram) | Studies (doxapram) | Trials (doxapram) | Recent Studies (post-2010) (doxapram) |
|---|---|---|---|---|---|
| 6 | 0 | 1 | 596 | 95 | 72 |
| Protein | Taxonomy | 2-ketodoxapram (IC50) | doxapram (IC50) |
|---|---|---|---|
| Potassium channel subfamily K member 3 | Rattus norvegicus (Norway rat) | 0.41 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aranda, JV; Bairam, A; Beharry, K; Branchaud, C; Laudignon, N; Papageorgiou, A; Rex, J | 1 |
| Aranda, JV; Bairam, A; Beharry, K; Blanchard, PW; Laudignon, N; Mullahoo, K | 1 |
| Beaudry, MA; Bradley, JM; LeGatt, DF | 1 |
| Baker, JR; Owens, EL; Peck, CC; Raybuck, BD; Schuster, BG | 1 |
| Bulsink, BM; Hagen, WR; Heering, HA; Meyer, TE | 1 |
| Abe, Y; Endo, T; Kamada, N; Kobayashi, M; Ohno, H; Suzuki, Y | 1 |
6 other study(ies) available for 2-ketodoxapram and doxapram
| Article | Year |
|---|---|
Doxapram metabolism in human fetal hepatic organ culture.
Topics: Biotransformation; Doxapram; Fetus; Gestational Age; Humans; Liver; Organ Culture Techniques | 1991 |
Pharmacodynamic effects and pharmacokinetic profiles of keto-doxapram and doxapram in newborn lambs.
Topics: Animals; Animals, Newborn; Doxapram; Metabolic Clearance Rate; Respiration; Sheep; Stimulation, Chemical | 1990 |
Simultaneous determination of doxapram and 2-ketodoxapram in plasma of neonates by gas chromatography.
Topics: Chromatography, Gas; Doxapram; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn | 1986 |
Normal pharmacokinetics of doxapramin in a patient with renal failure and hypothyroidism.
Topics: Aged; Doxapram; Humans; Hypothyroidism; Kidney Failure, Chronic; Kinetics; Male | 1981 |
Influence of charge and polarity on the redox potentials of high-potential iron-sulfur proteins: evidence for the existence of two groups.
Topics: Amino Acids; Bacteria; Doxapram; Electrochemistry; Electron Transport; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; Isoelectric Point; Osmolar Concentration; Oxidation-Reduction; Polylysine; Spectrum Analysis; Temperature; Thermodynamics | 1995 |
Development and validation of an LC-MS/MS method for simultaneously determining doxapram and keto-doxapram in human serum.
Topics: Calibration; Chromatography, Liquid; Doxapram; Drug Monitoring; Drug Stability; Humans; Limit of Detection; Propranolol; Reference Standards; Reproducibility of Results; Tandem Mass Spectrometry | 2017 |