2-keto-4-methylthiobutyric acid and methionine

2-keto-4-methylthiobutyric acid has been researched along with methionine in 101 studies

Research

Studies (101)

TimeframeStudies, this research(%)All Research%
pre-199050 (49.50)18.7374
1990's19 (18.81)18.2507
2000's15 (14.85)29.6817
2010's16 (15.84)24.3611
2020's1 (0.99)2.80

Authors

AuthorsStudies
Primrose, SB1
Billington, DC; Golding, BT; Primrose, SB1
Benevenga, NJ; Mitchell, AD1
Cooper, AJ2
Blaurock, B; Elstner, EF; Hippeli, S; Metz, N1
Cederbaum, AI; Dicker, E2
Benes, L; Stefek, M1
Abraham, DG; Cooper, AJ1
Blom, HJ; Ferenci, P; Grimm, G; Tangerman, A; Yap, SH1
Cederbaum, AI; Kukiełka, E2
Bunch, AW; Mansouri, S1
Brachet, P; Dupuis, L; Puigserver, A; Saunderson, CL1
Elstner, EF; Kröner, RP1
Ingelman-Sundberg, M; Terelius, Y1
Fukazawa, H; Ichihara, S; Takanohashi, Y; Tateishi, M; Tomisawa, H1
Elstner, EF; Schütz, W; Vogl, G1
Harel, S; Kanner, J1
Archibald, FS; Cheton, PL1
Gerok, W; Häussinger, D; Stehle, T1
Blom, HJ; Boers, GH; Gahl, WA; Tangerman, A; van den Elzen, JP1
Eicher, AL; Fellman, JH; Green, TR1
Cohen, G; Kang, J; Slivka, A1
Cederbaum, AI; Winston, GW1
Winterbourn, CC2
Adam, Z; Borochov, A; Mayak, S1
Blom, HJ; Boers, GH; Tangerman, A; Trijbels, JM; van den Elzen, JP; van Roessel, JJ1
Ayoubi, N; Robbins, JD; Stevens, JL1
Eklöw-Låstbom, L; Orrenius, S; Rossi, L; Thor, H1
Steele, RD1
Bremer, J; Davis, EJ; Davis-van Thienen, WI; Hokland, BM; Scislowski, PW1
Mårtensson, J1
Cederbaum, AI; Eibschutz, OM; Strekas, T; Winston, GW1
Byrd, RA; Robbins, JD; Stevens, JL1
Jones, SM; Yeaman, SJ1
Ferro, AJ; Marchitto, KS1
Adamczyk, R; Elstner, EF; Furch, A; Kröner, R2
Cohen, G; Lawrence, GD1
Brodelius, P1
Benevenga, NJ1
Diguiseppi, J; Fridovich, I1
Gold, MH; Kutsuki, H1
Berl, L; Cederbaum, AI; Harvey, W; Winston, GW1
Cederbaum, AI; Feierman, DE; Winston, GW1
Cederbaum, AI; Feierman, DE1
Cederbaum, AI; Cohen, G; Klein, SM; Lieber, CS1
Dixon, JL; Harper, AE1
Cederabum, AI; Cohen, G1
Toohey, JI1
Backlund, PS; Chang, CP; Smith, RA1
Kelley, RL; Reddy, CA1
Gasa, S; Ishimoto, M; Kaji, H; Kondo, H; Murao, M; Saito, K; Saito, N1
Benevenga, NJ; Dixon, JL1
Coudray, C; Favier, A; Rachidi, S1
Elstner, EF; Schempp, H; von Kruedener, S1
Chantepie, J; Dumontet, C; Fournet, G; Michal, Y; Quash, G; Roch, AM1
Pickard, K; Scislowski, PW1
Blarzino, C; Cini, C; Coccia, R; De Marco, C; Pensa, B1
De Bruyn, M; Deby, C; Deby-Dupont, G; Franchimont, P; Henrotin, Y; Lamy, M1
Chantegrel, B; Chantepie, J; Charlot, C; Deshayes, C; Doutheau, A; Ogier, G; Quash, G1
De Caro, J; Dupuis, L; Ferjancic-Biagini, A; Puigserver, A1
Chantegrel, B; Chantepie, J; Deshayes, C; Doutheau, A; Marvel, J; Michal, Y; Quash, G; Roch, AM1
Dumontet, C; Quash, G; Roch, AM1
Abeles, RH; Dai, Y; Wensink, PC1
Regoli, F; Winston, GW1
Beuscher, N; Dornisch, K; Elstner, EF; Grassmann, J; Hippeli, S; Rohnert, U1
Diegelman, P; Kruger, WD; Lu, ZJ; Markham, GD; Porter, CW; Subhi, AL; Tang, B1
Amárita, F; Arfi, K; Bonnarme, P; Spinnler, HE1
Bartram, S; Falk, KL; Gershenzon, J; Hick, A; Pickett, JA; Textor, S; Vogel, C1
Arshad, M; Khalid, A; Nazli, ZH; Zahir, ZA1
Chantepie, J; Charlot, C; Hamedi-Sangsari, F; Quash, G; Roch, AM; Thomas, V; Vila, J1
Lee, RF; Lemaire, DG; Winston, GW1
Binder, S; Schuster, J1
Chattopadhyay, MK; Tabor, CW; Tabor, H1
Elstner, EF; Kelber, O; Schempp, H; Weiser, D1
Kadariya, Y; Kruger, WD; Murphy, ME; Tang, B1
Achouri, Y; Noël, G; Van Schaftingen, E1
Findrik, Z; Vasić-Racki, D1
Baker, DH; Dilger, RN; Hoehler, D; Kobler, C; Weckbecker, C1
Fournet, G; Quash, G1
Kim, SJ; Kim, YC; Kim, YS; Kwon, DY1
Chinnadurai, G; Zhao, LZ1
Grossman, SR; Kovi, RC; Lyle, S; Paliwal, S; Parker, D; Rajeshkumar, B; Schiffer, CA; Straza, MW; Trenh, P; Whalen, GF1
de la Rebière, G; Deby, G; Franck, T; Mouithys-Mickalad, A; Sandersen, C; Serteyn, D1
Chory, J; Dai, X; Guo, Y; Ljung, K; Noel, JP; Novák, O; Zhao, Y; Zheng, Z1
Berkowitz, RS; Crum, C; Gali, R; He, H; Liu, S; May, T; Ng, SK; Ng, SW; Shoni, M; Yang, J1
Ashida, H; Nakano, T; Ohki, I; Yokota, A1
Bouchard, RJ; Kelsey, NA; Linseman, DA; Schroeder, EK; Stankiewicz, TR1
Grossman, SR; Hilbert, BJ; Royer, WE; Schiffer, CA1
Chen, J; Du, G; Hossain, GS; Li, J; Liu, L; Shin, HD; Wang, M1
Cui, G; Di, LJ; Wang, L; Wang, Y; Zhou, H1
Jia, KZ; Li, HM; Sun, LY; Tang, YJ; Xu, YH; Zhang, Q1
Coover, RA; Doughty, TW; Ellis, KC; Grossman, SR; Hilbert, BJ; Kellogg, GE; Korwar, S; Love, IM; Morris, BL; Parikh, HI; Royer, WE1
Chawla, AT; Cororaton, AD; Ellis, KC; Grossman, SR; Koblinski, JE; Korwar, S; Kovi, RC; Love, IM; Sumner, ET; Szomju, BB1
Alzubaidy, H; Andrés-Barrao, C; Benhamed, M; Colcombet, J; Daur, I; de Zélicourt, A; Depaepe, T; Guerard, F; Hirt, H; Jalal, R; Mariappan, KG; Rolli, E; Saad, MM; Synek, L; Van Der Straeten, D; Xie, Y1
Du, G; Liu, L; Nshimiyimana, P1
Alexander, RW; Muraski, M; Nilsson, E; Sharma, SB; Weekley, B1

Reviews

3 review(s) available for 2-keto-4-methylthiobutyric acid and methionine

ArticleYear
Evidence for alternative pathways of methionine catabolism.
    Advances in nutritional research, 1984, Volume: 6

    Topics: Animals; Betaine; Carbon Dioxide; Choline; Decarboxylation; Diet; Homocystinuria; Humans; Liver; Methionine; Models, Biological; Oxidation-Reduction; Propionates; S-Adenosylmethionine; Sarcosine; Transaminases

1984
Biochemistry of sulfur-containing amino acids.
    Annual review of biochemistry, 1983, Volume: 52

    Topics: Adenosine; Amino Acid Metabolism, Inborn Errors; Animals; Cysteine; Deoxyadenosines; Homocysteine; Humans; Methionine; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; S-Adenosylmethionine; Structure-Activity Relationship; Sulfur; Sulfurtransferases; Thionucleosides; Thiosulfate Sulfurtransferase

1983
Engineering of L-amino acid deaminases for the production of α-keto acids from L-amino acids.
    Bioengineered, 2019, Volume: 10, Issue:1

    Topics: Amidohydrolases; Amino Acids; Ammonia-Lyases; Bacillus subtilis; Biocatalysis; Directed Molecular Evolution; Escherichia coli; Hemiterpenes; Humans; Industrial Microbiology; Keto Acids; Ketoglutaric Acids; Methionine; Protein Engineering; Proteus; Pyruvic Acid

2019

Other Studies

98 other study(ies) available for 2-keto-4-methylthiobutyric acid and methionine

ArticleYear
Evaluation of the role of methional, 2-keto-4-methylthiobutyric acid and peroxidase in ethylene formation by Escherichia coli.
    Journal of general microbiology, 1977, Volume: 98, Issue:2

    Topics: Aerobiosis; Culture Media; Escherichia coli; Ethylenes; Hydrogen-Ion Concentration; Methionine; Peroxidases

1977
Biosynthesis of ethylene from methionine. Isolation of the putative intermediate 4-methylthio-2-oxobutanoate from culture fluids of bacteria and fungi.
    The Biochemical journal, 1979, Sep-15, Volume: 182, Issue:3

    Topics: Bacteria; Dinitrobenzenes; Ethylenes; Fungi; Glucose; Hydrazones; Hydrogen-Ion Concentration; Keto Acids; Light; Magnetic Resonance Spectroscopy; Methionine; Species Specificity

1979
The role of transamination in methionine oxidation in the rat.
    The Journal of nutrition, 1978, Volume: 108, Issue:1

    Topics: Amino Acids, Sulfur; Aminooxyacetic Acid; Animals; Keto Acids; Liver; Male; Methionine; Oxidation-Reduction; Phenylhydrazines; Rats; S-Adenosylmethionine; Tissue Distribution; Transaminases

1978
Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between L-phenylalanine and alpha-keto-gamma-methiolbutyrate.
    Analytical biochemistry, 1978, Volume: 89, Issue:2

    Topics: Animals; Cytosol; Female; Glutamine; Histidine; Kidney; Male; Methionine; Mitochondria; Molecular Weight; Phenylalanine; Pyruvates; Rats; Transaminases

1978
Oxidative destruction of biomolecules by gasoline engine exhaust products and detoxifying effects of the three-way catalytic converter.
    Archives of toxicology, 1992, Volume: 66, Issue:10

    Topics: Antioxidants; Ascorbic Acid; Automobiles; Carotenoids; Ethylenes; Gasoline; Glyceraldehyde-3-Phosphate Dehydrogenases; Methionine; Oxidation-Reduction; Reactive Oxygen Species; Serum Albumin, Bovine; Sulfhydryl Compounds; Vehicle Emissions; Xanthine Oxidase

1992
NADH-dependent generation of reactive oxygen species by microsomes in the presence of iron and redox cycling agents.
    Biochemical pharmacology, 1991, Jul-15, Volume: 42, Issue:3

    Topics: Animals; Edetic Acid; Ethanol; Ferric Compounds; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Lipid Peroxidation; Male; Methionine; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Oxygen; Paraquat; Pentetic Acid; Rats; Rats, Inbred Strains; Vitamin K

1991
Pyridoindole stobadine is a potent scavenger of hydroxyl radicals.
    FEBS letters, 1991, Dec-09, Volume: 294, Issue:3

    Topics: Animals; Binding, Competitive; Carbolines; Deoxyribose; Electron Transport; Ethylenes; Free Radical Scavengers; Hydroxides; Hydroxyl Radical; Kinetics; Male; Methionine; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Xanthine; Xanthine Oxidase; Xanthines

1991
Glutamine transaminase K and cysteine S-conjugate beta-lyase activity stains.
    Analytical biochemistry, 1991, Sep-02, Volume: 197, Issue:2

    Topics: Animals; Cysteine; Electrophoresis, Polyacrylamide Gel; Kidney; Lyases; Methionine; Molecular Weight; Nitroblue Tetrazolium; Phenylalanine; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Staining and Labeling; Transaminases

1991
The role of methanethiol in the pathogenesis of hepatic encephalopathy.
    Hepatology (Baltimore, Md.), 1991, Volume: 13, Issue:3

    Topics: Adult; Ammonia; Disulfides; Female; Hepatic Encephalopathy; Humans; Liver Diseases; Male; Methionine; Middle Aged; Sulfhydryl Compounds

1991
NADPH- and NADH-dependent oxygen radical generation by rat liver nuclei in the presence of redox cycling agents and iron.
    Archives of biochemistry and biophysics, 1990, Volume: 283, Issue:2

    Topics: Animals; Catalase; Cell Nucleus; Dimethyl Sulfoxide; Ferric Compounds; Free Radicals; Hydrogen Peroxide; Kinetics; Lipid Peroxidation; Liver; Methionine; NAD; NADP; Oxidation-Reduction; Paraquat; Rats; Superoxide Dismutase; Vitamin K

1990
Bacterial ethylene synthesis from 2-oxo-4-thiobutyric acid and from methionine.
    Journal of general microbiology, 1989, Volume: 135, Issue:11

    Topics: Ammonium Chloride; Bacteria; Chromobacterium; Culture Media; Escherichia coli; Ethylenes; Methionine; Nitrogen; Pseudomonas aeruginosa; Superoxides

1989
Oxidation of methionine and 2-hydroxy 4-methylthiobutanoic acid stereoisomers in chicken tissues.
    The British journal of nutrition, 1989, Volume: 62, Issue:1

    Topics: Animal Nutritional Physiological Phenomena; Animals; Carbon Radioisotopes; Chickens; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Methionine; Oxidation-Reduction; Oxidoreductases

1989
Model systems for testing anticataractic activities in rabbit eyes.
    Developments in ophthalmology, 1989, Volume: 17

    Topics: Animals; Antioxidants; Aqueous Humor; Cataract; Drug Evaluation, Preclinical; Free Radicals; In Vitro Techniques; Iodides; Male; Methionine; Models, Biological; Ophthalmic Solutions; Oxygen; Rabbits; Riboflavin

1989
Cytochrome P-450-dependent oxidase activity and hydroxyl radical production in micellar and membranous types of reconstituted systems.
    Biochemical pharmacology, 1988, Apr-01, Volume: 37, Issue:7

    Topics: Animals; Dimethyl Sulfoxide; Edetic Acid; Electron Transport; Hydroxides; Hydroxyl Radical; Male; Methionine; Micelles; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidoreductases; Rabbits

1988
Transamination of LTE4 by cysteine conjugate aminotransferase.
    Biochemical and biophysical research communications, 1988, Sep-30, Volume: 155, Issue:3

    Topics: Animals; Ketoglutaric Acids; Kidney; Leukotriene E4; Leukotrienes; Liver; Male; Mass Spectrometry; Methionine; Rats; Rats, Inbred Strains; SRS-A; Transaminases

1988
Enhancement of enzyme-catalyzed production of reactive oxygen species by suspensions of "crocidolite" asbestos fibres.
    Free radical research communications, 1986, Volume: 1, Issue:6

    Topics: Asbestos; Asbestos, Crocidolite; Catalase; Dihydrolipoamide Dehydrogenase; Ethylenes; Free Radicals; Methionine; NAD; Oxygen; Superoxide Dismutase; Suspensions; Xanthine Oxidase

1986
The generation of ferryl or hydroxyl radicals during interaction of haemproteins with hydrogen peroxide.
    Free radical research communications, 1988, Volume: 5, Issue:1

    Topics: Cytochrome c Group; Ethylenes; Ferric Compounds; Free Radicals; Hemeproteins; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Indicators and Reagents; Kinetics; Lipid Peroxidation; Methionine; Metmyoglobin

1988
Manganese complexes and the generation and scavenging of hydroxyl free radicals.
    Free radical biology & medicine, 1988, Volume: 5, Issue:5-6

    Topics: Ascorbic Acid; Chemical Phenomena; Chemistry; Diphosphates; DNA Damage; DNA, Bacterial; Edetic Acid; Ethylenes; Ferric Compounds; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Iron; Magnesium; Magnesium Compounds; Manganese; Mannitol; Methionine; Plasmids; Polyphosphates; Superoxides; Xanthine Oxidase

1988
Glutamine metabolism in isolated perfused rat liver. The transamination pathway.
    Biological chemistry Hoppe-Seyler, 1985, Volume: 366, Issue:6

    Topics: Alanine; Ammonia; Animals; Carrier Proteins; Cinnamates; Glutamates; Glutamic Acid; Glutaminase; Glutamine; Liver; Male; Methionine; Monocarboxylic Acid Transporters; Perfusion; Phenylpyruvic Acids; Rats; Rats, Inbred Strains; Transaminases; Urea

1985
Transamination of methionine in humans.
    Clinical science (London, England : 1979), 1989, Volume: 76, Issue:1

    Topics: Adult; Disulfides; Female; Humans; Liver; Male; Methionine; Methionine Adenosyltransferase; Propionates; Sulfhydryl Compounds; Time Factors

1989
Myeloperoxidase oxidation of sulfur-centered and benzoic acid hydroxyl radical scavengers.
    FEBS letters, 1985, Nov-11, Volume: 192, Issue:1

    Topics: Benzoates; Benzoic Acid; Binding, Competitive; Dimethyl Sulfoxide; Humans; Hydroxides; Hydroxyl Radical; Hypochlorous Acid; Kinetics; Mannitol; Methionine; Neutrophils; Oxidation-Reduction; Peroxidase; Sulfur; Superoxide Dismutase; Taurine

1985
Hydroxyl radicals and the toxicity of oral iron.
    Biochemical pharmacology, 1986, Feb-15, Volume: 35, Issue:4

    Topics: Administration, Oral; Animals; Ascorbic Acid; Ethylenes; Female; Ferrous Compounds; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Methionine; Oxidation-Reduction; Rats; Rats, Inbred Strains

1986
Differential effects of the cytochrome P-450/reductase ratio on the oxidation of ethanol and the hydroxyl radical scavenging agent 2-keto-4-thiomethylbutyric acid (KMBA).
    Biochemical pharmacology, 1986, Nov-15, Volume: 35, Issue:22

    Topics: Animals; Cytochrome P-450 Enzyme System; Edetic Acid; Ethanol; Hydroxides; Hydroxyl Radical; Male; Methionine; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Xanthine Oxidase

1986
The ability of scavengers to distinguish OH. production in the iron-catalyzed Haber-Weiss reaction: comparison of four assays for OH.
    Free radical biology & medicine, 1987, Volume: 3, Issue:1

    Topics: Benzoates; Benzoic Acid; Catalysis; Deoxyribose; Formates; Free Radicals; Hydroxides; Hydroxyl Radical; Iron; Methionine; Oxidation-Reduction; Xanthine Oxidase

1987
Free radicals play little role in the conversion of 1-aminocyclopropane-1-carboxylic acid to ethylene in carnation membrane fraction.
    Free radical research communications, 1986, Volume: 2, Issue:3

    Topics: Adenosine Triphosphate; Amino Acids; Amino Acids, Cyclic; Cobalt; Edetic Acid; Ethylenes; Free Radicals; Methionine; Microsomes; Oxidation-Reduction; Plants

1986
Differences between premenopausal women and young men in the transamination pathway of methionine catabolism, and the protection against vascular disease.
    European journal of clinical investigation, 1988, Volume: 18, Issue:6

    Topics: Adolescent; Adult; Fasting; Female; Homocysteine; Humans; Male; Menopause; Methionine; Middle Aged; Sulfhydryl Compounds; Vascular Diseases

1988
The role of mitochondrial matrix enzymes in the metabolism and toxicity of cysteine conjugates.
    The Journal of biological chemistry, 1988, Mar-05, Volume: 263, Issue:7

    Topics: Aminooxyacetic Acid; Animals; Benzothiazoles; Cysteine; Cytosol; Keto Acids; Kidney; Lyases; Male; Methionine; Mitochondria; Rats; Rats, Inbred Strains; Transaminases

1988
Effects of oxidative stress caused by hyperoxia and diquat. A study in isolated hepatocytes.
    Free radical research communications, 1986, Volume: 2, Issue:1-2

    Topics: Animals; Buthionine Sulfoximine; Cell Survival; Diquat; Glutathione; In Vitro Techniques; Lipid Peroxides; Liver; Methionine; Methionine Sulfoximine; NADP; Oxidation-Reduction; Oxygen; Pyridinium Compounds; Rats; Rats, Inbred Strains; Subcellular Fractions; Vitamin E

1986
Blood-brain barrier transport of the alpha-keto acid analogs of amino acids.
    Federation proceedings, 1986, Volume: 45, Issue:7

    Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Binding, Competitive; Biological Transport; Blood-Brain Barrier; Brain; Carboxylic Acids; Carrier Proteins; Coumaric Acids; Diffusion; Hydroxybutyrates; Keto Acids; Ketoglutaric Acids; Kinetics; Methionine; Monocarboxylic Acid Transporters; Propionates; Pyruvates; Pyruvic Acid; Starvation

1986
Methionine metabolism by rat muscle and other tissues. Occurrence of a new carnitine intermediate.
    The Biochemical journal, 1987, Oct-01, Volume: 247, Issue:1

    Topics: Acyltransferases; Animals; Carnitine; Chromatography, Thin Layer; Citric Acid Cycle; Male; Methionine; Mitochondria; Muscles; Rats; Rats, Inbred Strains; Tissue Distribution; Transaminases

1987
The occurrence of 4-methylthio-2-hydroxybutyrate in human urine.
    Analytical biochemistry, 1986, Volume: 154, Issue:1

    Topics: Animals; Humans; Hydroxybutyrates; In Vitro Techniques; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Methionine; Muscles; Myocardium; Rabbits; Substrate Specificity; Swine

1986
Complex-formation and reduction of ferric iron by 2-oxo-4-thiomethylbutyric acid, and the production of hydroxyl radicals.
    The Biochemical journal, 1986, Apr-15, Volume: 235, Issue:2

    Topics: Ethanol; Ferric Compounds; Free Radicals; Hydrogen Peroxide; Hydroxides; Iron; Macromolecular Substances; Methionine; Organometallic Compounds; Oxidation-Reduction; Phosphates; Photic Stimulation; Spectrophotometry

1986
A purified cysteine conjugate beta-lyase from rat kidney cytosol. Requirement for an alpha-keto acid or an amino acid oxidase for activity and identity with soluble glutamine transaminase K.
    The Journal of biological chemistry, 1986, Nov-25, Volume: 261, Issue:33

    Topics: Amino Acid Oxidoreductases; Animals; Chromatography, High Pressure Liquid; Cysteine; Cytosol; Kidney Cortex; Kinetics; L-Amino Acid Oxidase; Lyases; Male; Methionine; Rats; Rats, Inbred Strains; Spectrophotometry; Transaminases

1986
Oxidative decarboxylation of 4-methylthio-2-oxobutyrate by branched-chain 2-oxo acid dehydrogenase complex.
    The Biochemical journal, 1986, Jul-15, Volume: 237, Issue:2

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acetoacetates; Adipose Tissue; Decarboxylation; In Vitro Techniques; Ketone Oxidoreductases; Kinetics; Methionine; Multienzyme Complexes; Oxidation-Reduction; Pyruvate Dehydrogenase Complex

1986
The metabolism of 5'-methylthioadenosine and 5-methylthioribose 1-phosphate in Saccharomyces cerevisiae.
    Journal of general microbiology, 1985, Volume: 131, Issue:9

    Topics: Adenosine; Chromatography, Paper; Deoxyadenosines; Methionine; Ribosemonophosphates; Saccharomyces cerevisiae; Thioglycosides; Thionucleosides

1985
[Biochemical model reactions for cataract research].
    Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1985, Volume: 82, Issue:2

    Topics: Animals; Cataract; Cattle; Chromatography, Gas; Ethylenes; Light; Methionine; Models, Biological

1985
In vivo production of ethylene from 2-keto-4-methylthiobutyrate in mice.
    Biochemical pharmacology, 1985, Sep-15, Volume: 34, Issue:18

    Topics: Animals; Carbon Tetrachloride; Ethylenes; In Vitro Techniques; Kinetics; Liver; Male; Methionine; Mice; Vitamin E

1985
Biochemical model reactions for cataract research.
    Ophthalmic research, 1985, Volume: 17, Issue:5

    Topics: Animals; Aqueous Humor; Cataract; Cattle; Ethylenes; Lens, Crystalline; Light; Methionine; Potassium Iodide; Vitreous Body

1985
High-performance liquid chromatographic analysis of analogous amino and oxo acids for the determination of amino acid oxidase and transaminase activities.
    Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1984, Volume: 38, Issue:3

    Topics: Alanine Transaminase; Amino Acids; Chromatography, High Pressure Liquid; D-Alanine Transaminase; D-Amino-Acid Oxidase; Hemiterpenes; Keto Acids; Methionine; Transaminases

1984
Ethylene from 2-keto-4-thiomethyl butyric acid: the Haber-Weiss reaction.
    Archives of biochemistry and biophysics, 1980, Volume: 205, Issue:2

    Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Edetic Acid; Erythrocytes; Ethylenes; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Methionine; Pentetic Acid; Superoxides; Xanthine Oxidase

1980
Generation of hydroxyl radical and its involvement in lignin degradation by Phanerochaete chrysosporium.
    Biochemical and biophysical research communications, 1982, Nov-30, Volume: 109, Issue:2

    Topics: Agaricales; Aldehydes; Carbon Radioisotopes; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Lignin; Methionine; Sulfhydryl Compounds

1982
Inhibition of microsomal oxidation of alcohols and of hydroxyl-radical-scavenging agents by the iron-chelating agent desferrioxamine.
    The Biochemical journal, 1983, Jan-15, Volume: 210, Issue:1

    Topics: Alcohols; Aminopyrine; Animals; Benzoates; Benzoic Acid; Deferoxamine; Dimethyl Sulfoxide; Edetic Acid; Ferric Compounds; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Male; Methionine; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains

1983
Lactoferrin-catalysed hydroxyl radical production. Additional requirement for a chelating agent.
    The Biochemical journal, 1983, Jan-15, Volume: 210, Issue:1

    Topics: Aldehydes; Chelating Agents; Edetic Acid; Ethylenes; Ferric Compounds; Free Radicals; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Lactoferrin; Lactoglobulins; Methionine

1983
The generation of hydroxyl and alkoxyl radicals from the interaction of ferrous bipyridyl with peroxides.
    The Biochemical journal, 1983, Nov-15, Volume: 216, Issue:2

    Topics: Benzoates; Benzoic Acid; Catalase; Chemical Phenomena; Chemistry; Ethanol; Free Radicals; Hydroxides; Hydroxyl Radical; Methionine; Oxidation-Reduction; Peroxides; Superoxide Dismutase

1983
The role of iron chelates in hydroxyl radical production by rat liver microsomes, NADPH-cytochrome P-450 reductase and xanthine oxidase.
    Archives of biochemistry and biophysics, 1984, Volume: 232, Issue:1

    Topics: Animals; Catalase; Catalysis; Free Radicals; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Iron Chelating Agents; Male; Methionine; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Xanthine Oxidase

1984
The effect of EDTA and iron on the oxidation of hydroxyl radical scavenging agents and ethanol by rat liver microsomes.
    Biochemical and biophysical research communications, 1983, Oct-31, Volume: 116, Issue:2

    Topics: Animals; Dimethyl Sulfoxide; Edetic Acid; Ethanol; Iron; Male; Methionine; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains

1983
Increased microsomal oxidation of hydroxyl radical scavenging agents and ethanol after chronic consumption of ethanol.
    Archives of biochemistry and biophysics, 1983, Volume: 223, Issue:2

    Topics: Alcoholism; Animals; Azides; Dimethyl Sulfoxide; Enzyme Induction; Ethanol; Free Radicals; Humans; Hydroxides; Male; Methionine; Microsomes, Liver; Oxidation-Reduction; Rats

1983
Effects on plasma amino acid concentrations and hepatic branched-chain alpha-keto acid dehydrogenase activity of feeding rats diets containing 9 or 50% casein.
    The Journal of nutrition, 1984, Volume: 114, Issue:6

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids; Animals; Caseins; Dietary Proteins; Growth; Keto Acids; Ketone Oxidoreductases; Liver; Male; Methionine; Multienzyme Complexes; Rats; Rats, Inbred Strains

1984
Inhibition of the microsomal oxidation of ethanol and 1-butanol by the free-radical, spin-trapping agent 5,5-dimethyl-1-pyrroline-1-oxide.
    Archives of biochemistry and biophysics, 1980, Oct-15, Volume: 204, Issue:2

    Topics: Animals; Butanols; Chelating Agents; Cyclic N-Oxides; Edetic Acid; Ethanol; Ferric Compounds; Iron Chelating Agents; Male; Methionine; Microsomes, Liver; Oxidation-Reduction; Pentetic Acid; Pyrroles; Rats; Resins, Synthetic

1980
Ketomethylthiobutyric acid formation from methylthioadenosine: a diffusion assay.
    Archives of biochemistry and biophysics, 1983, Volume: 223, Issue:2

    Topics: Adenosine; Animals; Cell Line; Cells, Cultured; Cysteine; Deoxyadenosines; Diffusion; Methionine; Mice; Neoplasms, Experimental; Sulfhydryl Compounds; Thionucleosides

1983
Identification of 2-keto-4-methylthiobutyrate as an intermediate compound in methionine synthesis from 5'-methylthioadenosine.
    The Journal of biological chemistry, 1982, Apr-25, Volume: 257, Issue:8

    Topics: Adenosine; Animals; Deoxyadenosines; Kinetics; Liver; Magnesium; Methionine; Rats; Thionucleosides

1982
Ethylene production from alpha-oxo-gamma-methylthiobutyric acid is a sensitive measure of ligninolytic activity by Phanerochaete chrysosporium.
    The Biochemical journal, 1982, Aug-15, Volume: 206, Issue:2

    Topics: Basidiomycota; Ethylenes; Free Radicals; Lignin; Methionine; Methods

1982
Gas chromatographic and gas chromatographic--mass spectrometric studies on alpha-keto-gamma-methylthiobutyric acid in urine following ingestion of optical isomers of methionine.
    Journal of chromatography, 1980, Nov-14, Volume: 221, Issue:1

    Topics: Chromatography, Gas; Female; Gas Chromatography-Mass Spectrometry; Humans; Isomerism; Male; Methionine; Time Factors

1980
The decarboxylation of alpha-keto-gamma-methiolbutyrate in rat liver mitochondria.
    Biochemical and biophysical research communications, 1980, Dec-16, Volume: 97, Issue:3

    Topics: Animals; Male; Methionine; Mitochondria, Liver; Rats

1980
Effect of zinc on superoxide-dependent hydroxyl radical production in vitro.
    Biological trace element research, 1993, Volume: 38, Issue:3

    Topics: Copper; Edetic Acid; Ethylenes; Humans; Hydroxyl Radical; Indicators and Reagents; Iron; Ligands; Methionine; Plasma; Superoxide Dismutase; Superoxides; Xanthine Oxidase; Zinc

1993
Gas chromatographic differentiation between myeloperoxidase activity and Fenton-type oxidants.
    Free radical biology & medicine, 1995, Volume: 19, Issue:2

    Topics: Amino Acids; Amino Acids, Cyclic; Chromatography, Gas; Ethylenes; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Iron; Kinetics; Methionine; Oxidants; Oxidation-Reduction; Peroxidase; Reactive Oxygen Species; Xanthine; Xanthine Oxidase; Xanthines

1995
Methional derived from 4-methylthio-2-oxobutanoate is a cellular mediator of apoptosis in BAF3 lymphoid cells.
    The Biochemical journal, 1995, Feb-01, Volume: 305 ( Pt 3)

    Topics: Aldehydes; Animals; Apoptosis; Bone Marrow; Cell Division; Cell Line; DNA Damage; Flow Cytometry; HeLa Cells; Humans; Interleukin-3; Lymphocytes; Malondialdehyde; Methionine; Mice; Prostaglandin Antagonists

1995
The regulation of transaminative flux of methionine in rat liver mitochondria.
    Archives of biochemistry and biophysics, 1994, Nov-01, Volume: 314, Issue:2

    Topics: Animals; Glucagon; Homeostasis; Kinetics; Male; Methionine; Mitochondria, Liver; Rats; Rats, Inbred Strains; Starvation; Sulfhydryl Compounds; Transaminases

1994
Selenomethionine as substrate for glutamine transaminase.
    Biochemistry and molecular biology international, 1994, Volume: 32, Issue:1

    Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Kinetics; Liver; Methionine; Selenomethionine; Substrate Specificity; Transaminases

1994
Ferritin stimulation of hydroxyl radical production by rat liver nuclei.
    Archives of biochemistry and biophysics, 1994, Volume: 308, Issue:1

    Topics: Animals; Cell Nucleus; Chelating Agents; Dimethyl Sulfoxide; Edetic Acid; Ethanol; Ferritins; Free Radical Scavengers; Hydroxyl Radical; Iron Chelating Agents; Liver; Male; Methionine; NAD; NADP; Oxidation-Reduction; Pentetic Acid; Rats; Rats, Sprague-Dawley

1994
Production of active oxygen species by isolated human chondrocytes.
    British journal of rheumatology, 1993, Volume: 32, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cartilage; Cells, Cultured; Ethylenes; Female; Flow Cytometry; Free Radicals; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Hypoxia; Male; Methionine; Middle Aged; Reactive Oxygen Species; Tetradecanoylphorbol Acetate

1993
Contribution of 4-methylthio-2-oxobutanoate and its transaminase to the growth of methionine-dependent cells in culture. Effect of transaminase inhibitors.
    Biochemical pharmacology, 1993, Apr-22, Volume: 45, Issue:8

    Topics: Animals; Cell Division; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Methionine; Mice; Structure-Activity Relationship; Transaminases; Tumor Cells, Cultured

1993
In vitro oxidative decarboxylation of L-2-hydroxy-4-methylthiobutanoic acid by L-2-hydroxy acid oxidase A from chicken liver.
    Biochimie, 1995, Volume: 77, Issue:4

    Topics: Alcohol Oxidoreductases; Animals; Chickens; Chromatography, High Pressure Liquid; Decarboxylation; Kinetics; Liver; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methionine; Oxidation-Reduction; Propionates; Spectroscopy, Fourier Transform Infrared

1995
Altered methional homoeostasis is associated with decreased apoptosis in BAF3 bcl2 murine lymphoid cells.
    The Biochemical journal, 1996, Feb-01, Volume: 313 ( Pt 3)

    Topics: Aldehyde Dehydrogenase; Aldehydes; Animals; Apoptosis; Cell Line; Disulfiram; Enzyme Inhibitors; Homeostasis; Humans; Hydrogen Peroxide; Hydroxyl Radical; Lymphocytes; Malondialdehyde; Methionine; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quercetin

1996
Methionine dependence of tumor cells: programmed cell survival?
    Oncology research, 1996, Volume: 8, Issue:12

    Topics: Animals; Cell Survival; Humans; Methionine; Tumor Cells, Cultured

1996
One protein, two enzymes.
    The Journal of biological chemistry, 1999, Jan-15, Volume: 274, Issue:3

    Topics: Catalytic Domain; Chromatography, Gel; Chromatography, Ion Exchange; Cobalt; Dioxygenases; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Ferrous Compounds; Klebsiella pneumoniae; Methionine; Molecular Sequence Data; Nickel; Oxygenases; Recombinant Proteins

1999
Quantification of total oxidant scavenging capacity of antioxidants for peroxynitrite, peroxyl radicals, and hydroxyl radicals.
    Toxicology and applied pharmacology, 1999, Apr-15, Volume: 156, Issue:2

    Topics: Amidines; Antioxidants; Ascorbic Acid; Chromatography, Gas; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Methionine; Molsidomine; Nitrates; Nitric Oxide Donors; Oxidants; Oxidation-Reduction; Peroxides

1999
Antioxidant properties of essential oils. Possible explanations for their anti-inflammatory effects.
    Arzneimittel-Forschung, 2000, Volume: 50, Issue:2

    Topics: Amino Acids; Amino Acids, Cyclic; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Degranulation; Drug Combinations; Eucalyptus; Free Radical Scavengers; Granulocytes; Humans; In Vitro Techniques; Indicators and Reagents; Leukocytes; Methionine; Monoterpenes; Nitrates; Nitric Oxide; Oils, Volatile; Oxidants; Plant Oils; Plants, Medicinal; Terpenes

2000
Methylthioadenosine phosphorylase regulates ornithine decarboxylase by production of downstream metabolites.
    The Journal of biological chemistry, 2003, Dec-12, Volume: 278, Issue:50

    Topics: Cell Division; Cell Line, Tumor; Chromatography, High Pressure Liquid; Gene Deletion; Gene Expression Regulation, Enzymologic; Humans; Immunoblotting; Methionine; Models, Biological; Mutation; Ornithine Decarboxylase; Plasmids; Polyamines; Purine-Nucleoside Phosphorylase; Saccharomyces cerevisiae; Spermidine

2003
Catabolism of volatile sulfur compounds precursors by Brevibacterium linens and Geotrichum candidum, two microorganisms of the cheese ecosystem.
    Journal of biotechnology, 2003, Nov-06, Volume: 105, Issue:3

    Topics: Brevibacterium; Cheese; Food Microbiology; Geotrichum; Methionine; Sulfur Compounds; Volatilization

2003
Glucosinolate biosynthesis: demonstration and characterization of the condensing enzyme of the chain elongation cycle in Eruca sativa.
    Phytochemistry, 2004, Volume: 65, Issue:8

    Topics: 2-Isopropylmalate Synthase; Acetyl Coenzyme A; Brassicaceae; Cations, Divalent; Chloroplasts; Glucosinolates; Hydrolysis; Malate Synthase; Malonyl Coenzyme A; Mass Spectrometry; Methionine; Species Specificity; Substrate Specificity; Tritium

2004
Kinetics and effects of trace elements and electron complexes on 2-keto-4-methylthiobutyric acid-dependent biosynthesis of ethylene in soil.
    Letters in applied microbiology, 2004, Volume: 39, Issue:3

    Topics: Edetic Acid; Ethylenes; Hydroquinones; Kinetics; Lyases; Methionine; Sodium Benzoate; Soil Microbiology; Trace Elements

2004
4-methylthio 2-oxobutanoate transaminase: a specific target for antiproliferative agents.
    Bulletin du cancer, 2004, Volume: 91, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Asparagine; Cell Proliferation; D-Amino-Acid Oxidase; DNA Fragmentation; Fibroblasts; Glutamine; HeLa Cells; Humans; Liver; Methionine; Pyridoxal; Pyridoxamine; Rats; Transaminases

2004
Antioxidants and total oxyradical scavenging capacity during grass shrimp, Palaemonetes pugio, embryogenesis.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2004, Volume: 139, Issue:4

    Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Coenzymes; Female; Glutathione; Methionine; Palaemonidae; Peroxides; Reactive Oxygen Species; Ubiquinone; Xanthophylls

2004
The mitochondrial branched-chain aminotransferase (AtBCAT-1) is capable to initiate degradation of leucine, isoleucine and valine in almost all tissues in Arabidopsis thaliana.
    Plant molecular biology, 2005, Volume: 57, Issue:2

    Topics: Amino Acids, Branched-Chain; Aminobutyrates; Arabidopsis; Arabidopsis Proteins; Butyrates; Deamination; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glucuronidase; Hemiterpenes; Isoleucine; Keto Acids; Kinetics; Leucine; Methionine; Mitochondrial Proteins; Plants, Genetically Modified; Promoter Regions, Genetic; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seedlings; Substrate Specificity; Transaminases; Transcription, Genetic; Valine

2005
Studies on the regulation of ornithine decarboxylase in yeast: effect of deletion in the MEU1 gene.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Nov-08, Volume: 102, Issue:45

    Topics: Methionine; Ornithine Decarboxylase; Purine-Nucleoside Phosphorylase; Saccharomyces cerevisiae; Spermidine

2005
Radical scavenging and anti-inflammatory properties of STW 5 (Iberogast) and its components.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2006, Volume: 13 Suppl 5

    Topics: Anti-Inflammatory Agents; Free Radical Scavengers; Methionine; Peroxidase; Plant Extracts; Xanthine Oxidase

2006
The methionine salvage pathway compound 4-methylthio-2-oxobutanate causes apoptosis independent of down-regulation of ornithine decarboxylase.
    Biochemical pharmacology, 2006, Sep-28, Volume: 72, Issue:7

    Topics: Adenosine; Apoptosis; Blotting, Western; Caspase 3; Caspase 7; Caspases; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Eflornithine; Enzyme Activation; Growth Inhibitors; Humans; Methionine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Proteins; RNA Processing, Post-Transcriptional; RNA, Messenger; Tumor Suppressor Protein p53

2006
2-Keto-4-methylthiobutyrate, an intermediate in the methionine salvage pathway, is a good substrate for CtBP1.
    Biochemical and biophysical research communications, 2007, Jan-26, Volume: 352, Issue:4

    Topics: Alcohol Oxidoreductases; Catalysis; DNA-Binding Proteins; Humans; Methionine; Substrate Specificity

2007
Biotransformation of D-methionine into L-methionine in the cascade of four enzymes.
    Biotechnology and bioengineering, 2007, Dec-01, Volume: 98, Issue:5

    Topics: Algorithms; Amino Acid Oxidoreductases; Animals; Arthrobacter; Bioreactors; Biotechnology; Biotransformation; Candida; Catalase; Catalysis; Cattle; D-Amino-Acid Oxidase; Formate Dehydrogenases; Hydrogen-Ion Concentration; Kinetics; Methionine; Models, Chemical; NAD; Rhodococcus; Stereoisomerism

2007
2-keto-4-(methylthio)butyric acid (keto analog of methionine) is a safe and efficacious precursor of L-methionine in chicks.
    The Journal of nutrition, 2007, Volume: 137, Issue:8

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dose-Response Relationship, Drug; Methionine

2007
Methionine-derived metabolites in apoptosis: therapeutic opportunities for inhibitors of their metabolism in chemoresistant cancer cells.
    Current medicinal chemistry, 2009, Volume: 16, Issue:28

    Topics: Aldehydes; Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Lyases; Methionine; Mitochondria; Oxidation-Reduction; Prostaglandin Antagonists; Signal Transduction; Transaminases

2009
Peroxyl radical scavenging capacity of extracts and isolated components from selected medicinal plants.
    Archives of pharmacal research, 2010, Volume: 33, Issue:6

    Topics: Amidines; Drug Discovery; Ethylenes; Free Radical Scavengers; Genistein; Isoflavones; Kinetics; Magnolia; Medicine, East Asian Traditional; Methionine; Oxidants; Oxidative Stress; Peroxides; Plant Extracts; Plants, Medicinal; Pueraria; Salvia miltiorrhiza

2010
Incapacitating CtBP to kill cancer.
    Cell cycle (Georgetown, Tex.), 2010, Sep-15, Volume: 9, Issue:18

    Topics: Alcohol Oxidoreductases; Apoptosis; Apoptosis Regulatory Proteins; Colonic Neoplasms; DNA-Binding Proteins; Histone Deacetylases; Histone Demethylases; Humans; Intercalating Agents; Membrane Proteins; Methionine; Mitochondrial Proteins; RNA Interference

2010
Therapeutic targeting of C-terminal binding protein in human cancer.
    Cell cycle (Georgetown, Tex.), 2010, Sep-15, Volume: 9, Issue:18

    Topics: Alcohol Oxidoreductases; Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Chromatin Immunoprecipitation; Colonic Neoplasms; DNA-Binding Proteins; HCT116 Cells; Humans; Membrane Proteins; Methionine; Mice; Mice, Nude; Mitochondrial Proteins; Repressor Proteins; Transplantation, Heterologous; Tumor Suppressor Protein p53

2010
Modulating effects of acepromazine on the reactive oxygen species production by stimulated equine neutrophils.
    Veterinary anaesthesia and analgesia, 2011, Volume: 38, Issue:2

    Topics: Acepromazine; Animals; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Ethylenes; Horses; Hypnotics and Sedatives; Luminescent Measurements; Methionine; Neutrophils; Oxidation-Reduction; Reactive Oxygen Species; Tetradecanoylphorbol Acetate

2011
Coordination of auxin and ethylene biosynthesis by the aminotransferase VAS1.
    Nature chemical biology, 2013, Volume: 9, Issue:4

    Topics: Amino Acid Sequence; Amino Acids, Cyclic; Arabidopsis; Arabidopsis Proteins; Ethylenes; Indoleacetic Acids; Indoles; Methionine; Molecular Sequence Data; Mutation; Pyridoxal Phosphate; Transaminases; Tryptophan

2013
BRCA1 expression is epigenetically repressed in sporadic ovarian cancer cells by overexpression of C-terminal binding protein 2.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:6

    Topics: Alcohol Oxidoreductases; BRCA1 Protein; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Survival; Co-Repressor Proteins; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Methionine; Neoplasms, Glandular and Epithelial; Nerve Tissue Proteins; Ovarian Neoplasms; Phthalazines; Piperazines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic

2013
MtnBD is a multifunctional fusion enzyme in the methionine salvage pathway of Tetrahymena thermophila.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Amino Acid Sequence; Hydro-Lyases; Methionine; Molecular Sequence Data; Phylogeny; Protein Conformation; Ribulosephosphates; Signal Transduction; Tetrahymena thermophila

2013
C-terminal binding proteins are essential pro-survival factors that undergo caspase-dependent downregulation during neuronal apoptosis.
    Molecular and cellular neurosciences, 2013, Volume: 56

    Topics: Animals; Apoptosis; Carrier Proteins; Caspase 3; Down-Regulation; Female; Male; Methionine; Neurons; Potassium; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Staurosporine; Transcription Factors

2013
Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design.
    FEBS letters, 2014, May-02, Volume: 588, Issue:9

    Topics: Alcohol Oxidoreductases; Amino Acid Motifs; Catalytic Domain; Co-Repressor Proteins; Crystallography, X-Ray; DNA-Binding Proteins; Drug Design; Enzyme Inhibitors; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Methionine; Models, Molecular; Nerve Tissue Proteins; Protein Binding

2014
One-step biosynthesis of α-keto-γ-methylthiobutyric acid from L-methionine by an Escherichia coli whole-cell biocatalyst expressing an engineered L-amino acid deaminase from Proteus vulgaris.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Biocatalysis; Biotransformation; Cloning, Molecular; Deamination; Directed Molecular Evolution; Enzymes, Immobilized; Escherichia coli; Gene Expression; Lyases; Methionine; Mutagenesis, Site-Directed; Protein Engineering; Protein Transport; Proteus vulgaris; Substrate Specificity

2014
CtBP maintains cancer cell growth and metabolic homeostasis via regulating SIRT4.
    Cell death & disease, 2015, Jan-29, Volume: 6

    Topics: Alcohol Oxidoreductases; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Respiration; DNA-Binding Proteins; Glutamine; Glycolysis; Homeostasis; Humans; Hydrogen-Ion Concentration; Methionine; Mice; Mice, Nude; Mitochondrial Proteins; Models, Biological; Neoplasms; Sirtuins; Xenograft Model Antitumor Assays

2015
Clonostachys rosea demethiolase STR3 controls the conversion of methionine into methanethiol.
    Scientific reports, 2016, Feb-23, Volume: 6

    Topics: Amino Acid Sequence; Carbon-Sulfur Lyases; Chromatography, Liquid; Culture Media; Fungal Proteins; Gene Expression; Ketoglutaric Acids; Mass Spectrometry; Methionine; Recombinant Proteins; Saccharomycetales; Sequence Alignment; Substrate Specificity; Sulfhydryl Compounds

2016
Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP).
    Bioorganic & medicinal chemistry, 2016, 06-15, Volume: 24, Issue:12

    Topics: Alcohol Oxidoreductases; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Drug Design; Halogenation; Humans; Methionine; Models, Molecular; Neoplasms; Oximes; Phenylpropionates; Structure-Activity Relationship

2016
Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia.
    Oncogene, 2017, 08-17, Volume: 36, Issue:33

    Topics: Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Alcohol Oxidoreductases; Animals; beta Catenin; Carcinogenesis; Cell Line, Tumor; Co-Repressor Proteins; Colonic Neoplasms; Cyclin D; DNA-Binding Proteins; Fibroblasts; Humans; Methionine; Mice; Mice, Transgenic; Mutation; Nerve Tissue Proteins; Phosphoproteins

2017
Ethylene induced plant stress tolerance by Enterobacter sp. SA187 is mediated by 2-keto-4-methylthiobutyric acid production.
    PLoS genetics, 2018, Volume: 14, Issue:3

    Topics: Adaptation, Physiological; Arabidopsis; Enterobacter; Ethylenes; Gene Expression Regulation, Plant; Methionine; Plant Roots; Plant Shoots; Potassium; Stress, Physiological

2018
A Novel Aminoacyl-tRNA Synthetase Appended Domain Can Supply the Core Synthetase with Its Amino Acid Substrate.
    Genes, 2020, 11-07, Volume: 11, Issue:11

    Topics: Amino Acid Sequence; Amino Acids; Amino Acyl-tRNA Synthetases; Binding Sites; Methionine; Methionine-tRNA Ligase; Mycoplasma penetrans; Protein Domains; RNA, Transfer; Transaminases

2020