Protein | Taxonomy | 2-iodomelatonin (IC50) | resveratrol (IC50) |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
Chain A, Leukotriene A-4 hydrolase | Homo sapiens (human) | | 212 |
M18 aspartyl aminopeptidase | Plasmodium falciparum 3D7 | | 2.242 |
Vif | Human immunodeficiency virus 1 | | 25.31 |
DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | Homo sapiens (human) | | 25.31 |
Transient receptor potential cation channel subfamily A member 1 | Homo sapiens (human) | | 0.75 |
Amyloid-beta precursor protein | Homo sapiens (human) | | 2.6 |
Cytochrome P450 1A2 | Homo sapiens (human) | | 3 |
Prostaglandin G/H synthase 1 | Ovis aries (sheep) | | 2.025 |
Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | | 2.312 |
Luciferin 4-monooxygenase | Photinus pyralis (common eastern firefly) | | 0.0589 |
Cytochrome P450 3A4 | Homo sapiens (human) | | 0.6 |
Neuronal acetylcholine receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | | 0.685 |
DNA polymerase alpha catalytic subunit | Homo sapiens (human) | | 3.3 |
Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | | 4.9 |
Aromatase | Homo sapiens (human) | | 0.96 |
Cytochrome P450 2C9 | Homo sapiens (human) | | 7 |
Neuronal acetylcholine receptor subunit beta-2 | Rattus norvegicus (Norway rat) | | 0.685 |
Tyrosinase | Homo sapiens (human) | | 5.35 |
Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | | 1.3972 |
Nuclear factor NF-kappa-B p105 subunit | Homo sapiens (human) | | 2.5 |
Amine oxidase [flavin-containing] A | Homo sapiens (human) | | 2.4945 |
Prostaglandin G/H synthase 1 | Homo sapiens (human) | | 0.8517 |
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | | 2.312 |
Amine oxidase [flavin-containing] B | Homo sapiens (human) | | 5.01 |
Dipeptidyl peptidase 4 | Homo sapiens (human) | | 0.0006 |
Cytochrome P450 2C19 | Homo sapiens (human) | | 3 |
Prostaglandin G/H synthase 2 | Homo sapiens (human) | | 1.672 |
Prostaglandin G/H synthase 2 | Ovis aries (sheep) | | 3.49 |
Nuclear factor NF-kappa-B p100 subunit | Homo sapiens (human) | | 2.5 |
Transcription factor p65 | Homo sapiens (human) | | 2.5 |
Cytochrome P450 1B1 | Homo sapiens (human) | | 1.4 |
Transient receptor potential cation channel subfamily A member 1 | Rattus norvegicus (Norway rat) | | 1.63 |
large T antigen | Betapolyomavirus macacae | | 26.2 |
Authors | Studies |
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Boutin, JA; Calamini, B; Mesecar, AD; Santarsiero, BD | 1 |
Cushman, M; Maiti, A; Marler, L; Mesecar, AD; Pegan, SD; Pezzuto, JM; Reddy, PV; Sturdy, M | 1 |
Article | Year |
Chemical genetics reveals a complex functional ground state of neural stem cells.Nature chemical biology, 2007, Volume: 3, Issue:5
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.The Biochemical journal, 2008, Jul-01, Volume: 413, Issue:1
Topics: Binding Sites; Crystallography, X-Ray; Humans; Kinetics; Melatonin; Models, Molecular; Molecular Structure; Protein Binding; Quinone Reductases; Thermodynamics | 2008 |
Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities.Journal of medicinal chemistry, 2009, Apr-09, Volume: 52, Issue:7
Topics: Animals; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Benzodioxoles; Casimiroa; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Fruit; Humans; Mice; Models, Molecular; Quinolones; Quinone Reductases; Structure-Activity Relationship | 2009 |