Page last updated: 2024-09-03

2-iodomelatonin and luzindole

2-iodomelatonin has been researched along with luzindole in 20 studies

Compound Research Comparison

Studies
(2-iodomelatonin)
Trials
(2-iodomelatonin)
Recent Studies (post-2010)
(2-iodomelatonin)
Studies
(luzindole)
Trials
(luzindole)
Recent Studies (post-2010) (luzindole)
2450102651119

Protein Interaction Comparison

ProteinTaxonomy2-iodomelatonin (IC50)luzindole (IC50)
Melatonin receptor type 1CXenopus laevis (African clawed frog)2.4547

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (40.00)18.2507
2000's11 (55.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dubocovich, ML; Iacob, S; Masana, MI; Sauri, DM1
Bedini, A; Fraschini, F; Lucini, V; Mor, M; Pannacci, M; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Tarzia, G; Vacondio, F; Zuliani, V1
Amossé, C; Audinot, V; Bonnaud, A; Boutin, JA; Delagrange, P; Dromaint, S; Galizzi, JP; Guillaumet, G; Lahaye-Brasseur, C; Le Gall, A; Lefoulon, F; Lesieur, D; Mailliet, F; Malpaux, B; Nagel, N; Renard, P; Rodriguez, M1
Cecon, E; Jockers, R; Rivara, S; Witt-Enderby, PA; Zlotos, DP1
Dubocovich, ML1
Gan, J; Iuvone, PM1
Chong, NW; Sugden, D1
Barrett, P; Canning, SJ; Conway, S; Delagrange, P; Drew, JE; Guardiola-Lemaitre, B; Jockers, R; Morgan, PJ; Strosberg, AD1
Bucher, B; Gauer, F; Masson-Pévet, M; Pévet, P1
Flanders, S; Lew, MJ1
Angeloni, D; Fraschini, F; Lucini, V; Nonno, R; Pannacci, M; Stankov, BM1
Barrett, P; Conway, S; Delagrange, P; Drew, JE; Morgan, PJ; Mowat, ES1
Alonso-Bedate, M; Alonso-Gómez, AL; De Pedro, N; Delgado, MJ; Pinillos, ML1
Kravtsov, GM; Pang, SF; Poon, AM1
Castrucci, AM; Souza, AV; Visconti, MA1
Chen, Y; Fung, ML; Ip, SF; Liong, EC; Tipoe, GL; Tjong, YW1
Alonso-Bedate, M; Alonso-Gómez, AL; Delgado, MJ; Guijarro, A; Isorna, E1
Chen, Y; Fung, ML; Ip, SF; Tipoe, GL; Tjong, YW1
Chan, KW; Liu, VW; Pang, B; Shiu, SY; Tam, CW; Yao, KM1
Fujinoki, M1

Reviews

1 review(s) available for 2-iodomelatonin and luzindole

ArticleYear
Melatonin receptors in the central nervous system.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Brain Chemistry; Calcium; Chickens; Circadian Rhythm; Dopamine; Hypothalamus; Mammals; Melatonin; Mice; Mice, Inbred C3H; Periodicity; Pineal Gland; Receptors, Melatonin; Receptors, Neurotransmitter; Reproduction; Retina; Seasons; Suprachiasmatic Nucleus; Tryptamines

1991

Other Studies

19 other study(ies) available for 2-iodomelatonin and luzindole

ArticleYear
Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:3

    Topics: Animals; Cell Line; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Melatonin; Rabbits; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Receptors, Presynaptic; Recombinant Proteins; Retina

1997
Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.
    Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8

    Topics: Ligands; Melatonin; Models, Molecular; Models, Statistical; Pyrroles; Quantitative Structure-Activity Relationship; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin

2003
New selective ligands of human cloned melatonin MT1 and MT2 receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 367, Issue:6

    Topics: Animals; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Humans; Ligands; Melatonin; Protein Binding; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2

2003
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.
    Journal of medicinal chemistry, 2014, Apr-24, Volume: 57, Issue:8

    Topics: Animals; Binding Sites; Depressive Disorder; Humans; Ligands; Melatonin; Models, Molecular; Protein Multimerization; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship

2014
Melatonin receptor-mediated inhibition of cyclic AMP accumulation in chick retinal cell cultures.
    Journal of neurochemistry, 1994, Volume: 63, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; 5-Methoxytryptamine; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Iodine Radioisotopes; Melatonin; Neurons; Pertussis Toxin; Photoreceptor Cells; Potassium; Receptors, Cell Surface; Receptors, Melatonin; Retina; Second Messenger Systems; Structure-Activity Relationship; Tryptamines; Virulence Factors, Bordetella

1994
Thermodynamic analysis of agonist and antagonist binding to the chicken brain melatonin receptor.
    British journal of pharmacology, 1994, Volume: 111, Issue:1

    Topics: Animals; Binding Sites; Brain; Chickens; Guanosine Triphosphate; Iodine Radioisotopes; Kinetics; Melatonin; Receptors, Cell Surface; Receptors, Melatonin; Regression Analysis; Temperature; Thermodynamics; Tryptamines

1994
Identification of Mel1a melatonin receptors in the human embryonic kidney cell line HEK293: evidence of G protein-coupled melatonin receptors which do not mediate the inhibition of stimulated cyclic AMP levels.
    FEBS letters, 1997, Apr-21, Volume: 407, Issue:1

    Topics: Binding, Competitive; Cell Line; Colforsin; Cyclic AMP; Genomic Library; GTP-Binding Proteins; Humans; Kidney; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Signal Transduction; Tryptamines

1997
Vasoconstrictor effects of various melatonin analogs on the rat tail artery in the presence of phenylephrine.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:2

    Topics: Acetamides; Animals; Dose-Response Relationship, Drug; Drug Interactions; Endothelium; Male; Melatonin; Muscle, Smooth; Nerve Endings; Norepinephrine; Perfusion; Phenylephrine; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympathetic Nervous System; Tail; Tryptamines; Vasoconstriction

1999
Mechanisms of melatonin-induced vasoconstriction in the rat tail artery: a paradigm of weak vasoconstriction.
    British journal of pharmacology, 1999, Volume: 126, Issue:6

    Topics: Acetamides; Animals; Anticonvulsants; Arteries; Calcium Channel Blockers; Charybdotoxin; Colforsin; Dose-Response Relationship, Drug; Hypnotics and Sedatives; In Vitro Techniques; Indoles; Male; Melatonin; Nifedipine; Nitroprusside; Potassium Channels; Rats; Rats, Sprague-Dawley; Tail; Tryptamines; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins

1999
Ligand efficacy and potency at recombinant human MT2 melatonin receptors: evidence for agonist activity of some mt1-antagonists.
    British journal of pharmacology, 1999, Volume: 127, Issue:5

    Topics: 3T3 Cells; Animals; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Melatonin; Mice; Pertussis Toxin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Recombinant Proteins; Tryptamines; Virulence Factors, Bordetella

1999
Serine residues 110 and 114 are required for agonist binding but not antagonist binding to the melatonin MT(1) receptor.
    Biochemical and biophysical research communications, 2001, Apr-20, Volume: 282, Issue:5

    Topics: Acetamides; Amides; Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; COS Cells; Cyclic AMP; Dose-Response Relationship, Drug; Heterotrimeric GTP-Binding Proteins; Humans; Indoles; Melatonin; Mutagenesis, Site-Directed; Naphthalenes; Protein Binding; Radioligand Assay; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Recombinant Fusion Proteins; Serine; Structure-Activity Relationship; Transfection; Tryptamines

2001
Food intake inhibition by melatonin in goldfish (Carassius auratus).
    Physiology & behavior, 2001, Volume: 72, Issue:5

    Topics: Animals; Antioxidants; Depression, Chemical; Eating; Goldfish; Injections, Intraperitoneal; Injections, Intraventricular; Melatonin; Tryptamines

2001
Receptor-mediated modulation of avian caecal muscle contraction by melatonin: role of tyrosine protein kinase.
    Journal of pineal research, 2002, Volume: 32, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apamin; Binding, Competitive; Cecum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Indoles; Melatonin; Muscle Contraction; Muscle, Smooth; Naphthalenes; Potassium Channels; Protein-Tyrosine Kinases; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Tetrahydronaphthalenes; Tryptamines

2002
Melatonin biological activity and binding sites in human melanoma cells.
    Journal of pineal research, 2003, Volume: 34, Issue:4

    Topics: Binding Sites; Binding, Competitive; Cell Division; Humans; Iodine Radioisotopes; Melanoma; Melatonin; Monophenol Monooxygenase; Prazosin; Serotonin; Tryptamines; Tumor Cells, Cultured

2003
Melatonin attenuates rat carotid chemoreceptor response to hypercapnic acidosis.
    Journal of pineal research, 2004, Volume: 36, Issue:1

    Topics: Acidosis, Respiratory; Animals; Calcium; Carotid Body; Chemoreceptor Cells; Electrophysiology; Fura-2; Hypercapnia; Melatonin; Rats; Rats, Sprague-Dawley; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Melatonin; Tetrahydronaphthalenes; Tryptamines

2004
Characterization of melatonin binding sites in the brain and retina of the frog Rana perezi.
    General and comparative endocrinology, 2004, Volume: 135, Issue:3

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Diencephalon; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Kinetics; Magnesium; Melatonin; Pertussis Toxin; Radioligand Assay; Ranidae; Receptors, Melatonin; Retina; Sodium; Subcellular Fractions; Superior Colliculi; Telencephalon; Tetrahydronaphthalenes; Tryptamines

2004
Melatonin enhances the hypoxic response of rat carotid body chemoreceptor.
    Journal of pineal research, 2005, Volume: 38, Issue:3

    Topics: Animals; Calcium; Carotid Body; Chemoreceptor Cells; Circadian Rhythm; Hypoxia; In Vitro Techniques; Melatonin; Rats; Rats, Sprague-Dawley; Receptors, Melatonin; Respiration; Tetrahydronaphthalenes; Tryptamines

2005
Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance.
    Journal of pineal research, 2008, Volume: 45, Issue:4

    Topics: Analysis of Variance; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Epithelial Cells; Gene Expression Regulation; Growth Substances; Humans; Immunoblotting; Immunohistochemistry; Male; Melatonin; Prostate; Prostatic Neoplasms; Protein Kinases; Receptors, Androgen; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Tetrahydronaphthalenes; Tryptamines

2008
Melatonin-enhanced hyperactivation of hamster sperm.
    Reproduction (Cambridge, England), 2008, Volume: 136, Issue:5

    Topics: Animals; Calcium; Cells, Cultured; Cricetinae; Culture Media; Dose-Response Relationship, Drug; Male; Melatonin; Mesocricetus; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Serum Albumin; Sperm Motility; Spermatozoa; Stimulation, Chemical; Tetrahydronaphthalenes; Time; Tryptamines

2008