2-iodomelatonin has been researched along with 6-hydroxymelatonin in 10 studies
| Studies (2-iodomelatonin) | Trials (2-iodomelatonin) | Recent Studies (post-2010) (2-iodomelatonin) | Studies (6-hydroxymelatonin) | Trials (6-hydroxymelatonin) | Recent Studies (post-2010) (6-hydroxymelatonin) |
|---|---|---|---|---|---|
| 245 | 0 | 10 | 154 | 12 | 27 |
| Protein | Taxonomy | 2-iodomelatonin (IC50) | 6-hydroxymelatonin (IC50) |
|---|---|---|---|
| rac GTPase-activating protein 1 isoform a | Homo sapiens (human) | 52.26 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dubocovich, ML | 1 |
| Dubocovich, ML; Iacob, S; Masana, MI; Sauri, DM | 1 |
| Beresford, IJ; Brown, J; Browning, C; Coughlan, J; Dubocovich, ML; Foord, SM; Hagan, RM; North, PC; Starkey, SJ | 1 |
| Balsamini, C; Bordi, F; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Stankov, BM; Tarzia, G | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Laborda, P; Shi, XC; Wang, SY | 1 |
| Flügge, G; Laitinen, JT; Saavedra, JM | 1 |
| Barrett, P; Canning, SJ; Conway, S; Delagrange, P; Drew, JE; Guardiola-Lemaitre, B; Jockers, R; Morgan, PJ; Strosberg, AD | 1 |
| Garratt, PJ; Pickering, H; Sugden, D; Teh, MT | 1 |
| Chan, HC; Lui, KM; Poon, AM; Wong, WS | 1 |
1 review(s) available for 2-iodomelatonin and 6-hydroxymelatonin
| Article | Year |
|---|---|
Indole-based melatonin analogues: Synthetic approaches and biological activity.
Topics: Animals; Dose-Response Relationship, Drug; Humans; Indoles; Ligands; Melatonin; Molecular Structure; Receptors, Melatonin; Structure-Activity Relationship | 2020 |
9 other study(ies) available for 2-iodomelatonin and 6-hydroxymelatonin
| Article | Year |
|---|---|
Characterization of a retinal melatonin receptor.
Topics: Animals; Calcium; Chickens; Corpus Striatum; Dopamine; In Vitro Techniques; Indoles; Melatonin; Olfactory Bulb; Rabbits; Receptors, Cell Surface; Receptors, Melatonin; Retina; Structure-Activity Relationship; Tryptamines | 1985 |
Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor.
Topics: Animals; Cell Line; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Melatonin; Rabbits; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Receptors, Presynaptic; Recombinant Proteins; Retina | 1997 |
GR196429: a nonindolic agonist at high-affinity melatonin receptors.
Topics: Animals; Binding Sites; Brain; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Humans; Indoles; Male; Rabbits; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Retina | 1998 |
Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study.
Topics: Animals; Ligands; Melatonin; Models, Molecular; Molecular Conformation; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Structure-Activity Relationship; Superior Colliculi | 1998 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Characterization of melatonin receptors in the rat area postrema: modulation of affinity with cations and guanine nucleotides.
Topics: Animals; Autoradiography; Binding Sites; Binding, Competitive; Calcium Chloride; Cations, Divalent; Cerebral Ventricles; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Magnesium Chloride; Male; Melatonin; Rats; Rats, Inbred Strains; Receptors, Melatonin; Receptors, Neurotransmitter; Serotonin; Thionucleotides | 1990 |
Identification of Mel1a melatonin receptors in the human embryonic kidney cell line HEK293: evidence of G protein-coupled melatonin receptors which do not mediate the inhibition of stimulated cyclic AMP levels.
Topics: Binding, Competitive; Cell Line; Colforsin; Cyclic AMP; Genomic Library; GTP-Binding Proteins; Humans; Kidney; Melatonin; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Sequence Analysis, DNA; Serotonin; Signal Transduction; Tryptamines | 1997 |
Melatonin receptor pharmacology: toward subtype specificity.
Topics: 3T3 Cells; 5-Methoxytryptamine; Acetylation; Animals; Binding Sites; Binding, Competitive; Clone Cells; Cloning, Molecular; GTP-Binding Proteins; Humans; Ligands; Melanocytes; Melanophores; Melatonin; Methylation; Mice; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Recombinant Fusion Proteins; Serotonin; Species Specificity; Structure-Activity Relationship; Transfection; Tryptamines; Xenopus laevis | 1997 |
Effect of melatonin on chloride secretion by human colonic T84 cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Calcium Channel Blockers; Cell Line; Chloride Channels; Chlorides; Colon; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Imines; Melatonin; ortho-Aminobenzoates; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Virulence Factors, Bordetella | 1998 |