2-iodomelatonin has been researched along with 6-chloromelatonin in 22 studies
| Studies (2-iodomelatonin) | Trials (2-iodomelatonin) | Recent Studies (post-2010) (2-iodomelatonin) | Studies (6-chloromelatonin) | Trials (6-chloromelatonin) | Recent Studies (post-2010) (6-chloromelatonin) |
|---|---|---|---|---|---|
| 245 | 0 | 10 | 62 | 0 | 11 |
| Protein | Taxonomy | 2-iodomelatonin (IC50) | 6-chloromelatonin (IC50) |
|---|---|---|---|
| Melatonin receptor type 1A | Homo sapiens (human) | 0.0024 | |
| Melatonin receptor type 1B | Homo sapiens (human) | 0.0024 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 13 (59.09) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Dubocovich, ML | 1 |
| Biella, G; Duranti, A; Fraschini, F; Lucini, V; Salvatori, A; Spadoni, G; Stankov, B | 1 |
| Copinga, S; Dubocovich, ML; Grol, CJ; Horn, AS; Tepper, PG | 1 |
| Dubocovich, ML; Iacob, S; Masana, MI; Sauri, DM | 1 |
| Beresford, IJ; Brown, J; Browning, C; Coughlan, J; Dubocovich, ML; Foord, SM; Hagan, RM; North, PC; Starkey, SJ | 1 |
| Balsamini, C; Bordi, F; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Stankov, BM; Tarzia, G | 1 |
| Bedini, A; Fraschini, F; Lucini, V; Mor, M; Pannacci, M; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Tarzia, G; Vacondio, F; Zuliani, V | 1 |
| Amossé, C; Audinot, V; Bonnaud, A; Boutin, JA; Delagrange, P; Dromaint, S; Galizzi, JP; Guillaumet, G; Lahaye-Brasseur, C; Le Gall, A; Lefoulon, F; Lesieur, D; Mailliet, F; Malpaux, B; Nagel, N; Renard, P; Rodriguez, M | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Cecon, E; Jockers, R; Rivara, S; Witt-Enderby, PA; Zlotos, DP | 1 |
| Laborda, P; Shi, XC; Wang, SY | 1 |
| Pang, CS; Pang, SF | 1 |
| Lu, Y; Pang, SF; Yuan, H | 1 |
| Kehajova, J; Persengiev, S | 1 |
| Gan, J; Iuvone, PM | 1 |
| Lee, PP; Pang, SF; Poon, AM; Song, Y | 1 |
| Pang, SF; Wang, XL; Yuan, H | 1 |
| Crocker, C; Niles, LP; Ying, SW | 1 |
| Bucher, B; Gauer, F; Masson-Pévet, M; Pévet, P | 1 |
| Burkhardt, S; Dose, A; Hardeland, R; Poeggeler, B; Schoenke, M; Thuermann, S | 1 |
| Alonso-Bedate, M; Alonso-Gómez, AL; Delgado, MJ; Guijarro, A; Isorna, E | 1 |
| Fujinoki, M | 1 |
1 review(s) available for 2-iodomelatonin and 6-chloromelatonin
| Article | Year |
|---|---|
Indole-based melatonin analogues: Synthetic approaches and biological activity.
Topics: Animals; Dose-Response Relationship, Drug; Humans; Indoles; Ligands; Melatonin; Molecular Structure; Receptors, Melatonin; Structure-Activity Relationship | 2020 |
21 other study(ies) available for 2-iodomelatonin and 6-chloromelatonin
| Article | Year |
|---|---|
Characterization of a retinal melatonin receptor.
Topics: Animals; Calcium; Chickens; Corpus Striatum; Dopamine; In Vitro Techniques; Indoles; Melatonin; Olfactory Bulb; Rabbits; Receptors, Cell Surface; Receptors, Melatonin; Retina; Structure-Activity Relationship; Tryptamines | 1985 |
2-Substituted 5-methoxy-N-acyltryptamines: synthesis, binding affinity for the melatonin receptor, and evaluation of the biological activity.
Topics: Animals; Binding Sites; Cricetinae; Male; Mesocricetus; Quail; Rabbits; Receptors, Cell Surface; Receptors, Melatonin; Structure-Activity Relationship; Tryptamines | 1993 |
2-Amido-8-methoxytetralins: a series of nonindolic melatonin-like agents.
Topics: Animals; Binding, Competitive; Calcium; Cell Membrane; Chickens; Dopamine; Iodine Radioisotopes; Melatonin; Rabbits; Receptors, Cell Surface; Receptors, Melatonin; Retina; Structure-Activity Relationship; Tetrahydronaphthalenes | 1993 |
Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor.
Topics: Animals; Cell Line; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Melatonin; Rabbits; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Receptors, Presynaptic; Recombinant Proteins; Retina | 1997 |
GR196429: a nonindolic agonist at high-affinity melatonin receptors.
Topics: Animals; Binding Sites; Brain; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Humans; Indoles; Male; Rabbits; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Retina | 1998 |
Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study.
Topics: Animals; Ligands; Melatonin; Models, Molecular; Molecular Conformation; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Structure-Activity Relationship; Superior Colliculi | 1998 |
Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.
Topics: Ligands; Melatonin; Models, Molecular; Models, Statistical; Pyrroles; Quantitative Structure-Activity Relationship; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin | 2003 |
New selective ligands of human cloned melatonin MT1 and MT2 receptors.
Topics: Animals; Cell Line; CHO Cells; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Humans; Ligands; Melatonin; Protein Binding; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2 | 2003 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.
Topics: Animals; Binding Sites; Depressive Disorder; Humans; Ligands; Melatonin; Models, Molecular; Protein Multimerization; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship | 2014 |
High affinity specific binding of 2-[125I]iodomelatonin by spleen membrane preparations of chicken.
Topics: Animals; Chickens; Circadian Rhythm; Iodine Radioisotopes; Kinetics; Melatonin; Random Allocation; Receptors, Melatonin; Receptors, Neurotransmitter; Spleen | 1992 |
Binding characteristics and regional distribution of [125I]iodomelatonin binding sites in the brain of the human fetus.
Topics: Binding, Competitive; Brain; Brain Chemistry; Fetus; Humans; Hypothalamus; Indoles; Melatonin; Neurotransmitter Agents; Receptors, Melatonin; Receptors, Neurotransmitter; Serotonin | 1991 |
Inhibitory action of melatonin and structurally related compounds on testosterone production by mouse Leydig cells in vitro.
Topics: 5-Methoxytryptamine; Animals; Dose-Response Relationship, Drug; Indoles; Leydig Cells; Male; Melatonin; Mice; Mice, Inbred BALB C; Testosterone | 1991 |
Functional interaction of melatonin receptors and D1 dopamine receptors in cultured chick retinal neurons.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Animals; Benzazepines; Cells, Cultured; Chick Embryo; Cyclic AMP; GTP-Binding Proteins; Haloperidol; Inositol Phosphates; Melatonin; Models, Neurological; Neurons; Pertussis Toxin; Receptors, Cell Surface; Receptors, Dopamine D1; Receptors, Melatonin; Retina; Signal Transduction; Synaptic Transmission; Virulence Factors, Bordetella | 1995 |
Putative melatonin receptors in the male guinea pig kidney.
Topics: Animals; Binding Sites; Guinea Pigs; Kidney Cortex; Kidney Medulla; Male; Melatonin; Radioimmunoassay; Receptors, Cell Surface; Receptors, Melatonin; Subcellular Fractions | 1993 |
Specific binding of [125I]iodomelatonin in pigeon and quail spleen membrane preparations and effect with hydrocortisone-treatment.
Topics: Animals; Binding Sites; Cell Membrane; Circadian Rhythm; Columbidae; Hydrocortisone; Iodine Radioisotopes; Melatonin; Quail; Spleen | 1993 |
Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin.
Topics: Adenylyl Cyclase Inhibitors; Cell Division; Cell Membrane; Colforsin; Cyclic AMP; DNA, Neoplasm; Humans; Indoles; Iodine Radioisotopes; Kinetics; Melanoma; Melatonin; Nucleotides; Receptors, Melatonin; Receptors, Neurotransmitter; Tumor Cells, Cultured | 1993 |
Vasoconstrictor effects of various melatonin analogs on the rat tail artery in the presence of phenylephrine.
Topics: Acetamides; Animals; Dose-Response Relationship, Drug; Drug Interactions; Endothelium; Male; Melatonin; Muscle, Smooth; Nerve Endings; Norepinephrine; Perfusion; Phenylephrine; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympathetic Nervous System; Tail; Tryptamines; Vasoconstriction | 1999 |
Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs.
Topics: 5-Methoxytryptamine; Free Radical Scavengers; Hydroxyl Radical; Melatonin; Molecular Biology; Oxidation-Reduction; Serotonin; Solubility; Structure-Activity Relationship; Superoxides; Tryptamines | 2002 |
Characterization of melatonin binding sites in the brain and retina of the frog Rana perezi.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Diencephalon; Guanosine 5'-O-(3-Thiotriphosphate); Intracellular Membranes; Kinetics; Magnesium; Melatonin; Pertussis Toxin; Radioligand Assay; Ranidae; Receptors, Melatonin; Retina; Sodium; Subcellular Fractions; Superior Colliculi; Telencephalon; Tetrahydronaphthalenes; Tryptamines | 2004 |
Melatonin-enhanced hyperactivation of hamster sperm.
Topics: Animals; Calcium; Cells, Cultured; Cricetinae; Culture Media; Dose-Response Relationship, Drug; Male; Melatonin; Mesocricetus; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Serum Albumin; Sperm Motility; Spermatozoa; Stimulation, Chemical; Tetrahydronaphthalenes; Time; Tryptamines | 2008 |