Compounds > 2-hydroxyimipramine
Page last updated: 2024-09-02

2-hydroxyimipramine and sulbactam

2-hydroxyimipramine has been researched along with sulbactam in 2 studies

Compound Research Comparison

Studies
(2-hydroxyimipramine)		Trials
(2-hydroxyimipramine)		Recent Studies (post-2010)
(2-hydroxyimipramine)		Studies
(sulbactam)		Trials
(sulbactam)		Recent Studies (post-2010) (sulbactam)
30301,844297488

Protein Interaction Comparison

ProteinTaxonomy2-hydroxyimipramine (IC50)sulbactam (IC50)
Beta-lactamase Escherichia coli6.2
Beta-lactamase Shouchella clausii0.075
Beta-lactamase Pseudomonas aeruginosa0.37
Beta-lactamase Pseudomonas aeruginosa3
Beta-lactamase Aeromonas allosaccharophila4
Beta-lactamaseStaphylococcus aureus6.5
Beta-lactamaseEnterobacter cloacae1.4
Beta-lactamase TEMEscherichia coli4.3
Beta-lactamase Acinetobacter pittii1.12
Beta-lactamase Acinetobacter pittii7.758
Beta-lactamase Pseudomonas aeruginosa3
Beta-lactamase Escherichia coli2.4

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1

Other Studies

2 other study(ies) available for 2-hydroxyimipramine and sulbactam

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009