2-hydroxyimipramine has been researched along with nomifensine in 2 studies
| Studies (2-hydroxyimipramine) | Trials (2-hydroxyimipramine) | Recent Studies (post-2010) (2-hydroxyimipramine) | Studies (nomifensine) | Trials (nomifensine) | Recent Studies (post-2010) (nomifensine) |
|---|---|---|---|---|---|
| 30 | 3 | 0 | 1,127 | 111 | 65 |
| Protein | Taxonomy | 2-hydroxyimipramine (IC50) | nomifensine (IC50) |
|---|---|---|---|
| D | Rattus norvegicus (Norway rat) | 2.724 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 2.724 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.631 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.1642 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 2.724 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 2.724 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 8.7096 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 3.115 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.0316 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 2.724 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.0781 | |
| Transporter | Rattus norvegicus (Norway rat) | 2.7033 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
2 other study(ies) available for 2-hydroxyimipramine and nomifensine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |