2-hydroxyimipramine has been researched along with montelukast in 2 studies
| Studies (2-hydroxyimipramine) | Trials (2-hydroxyimipramine) | Recent Studies (post-2010) (2-hydroxyimipramine) | Studies (montelukast) | Trials (montelukast) | Recent Studies (post-2010) (montelukast) |
|---|---|---|---|---|---|
| 30 | 3 | 0 | 1,965 | 598 | 777 |
| Protein | Taxonomy | 2-hydroxyimipramine (IC50) | montelukast (IC50) |
|---|---|---|---|
| Epidermal growth factor receptor | Homo sapiens (human) | 3.197 | |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 4.702 | |
| Beta-2 adrenergic receptor | Homo sapiens (human) | 3.488 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 2.689 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 3.919 | |
| Adenosine receptor A3 | Homo sapiens (human) | 0.434 | |
| Cytochrome P450 2C8 | Homo sapiens (human) | 0.7 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 8.045 | |
| Beta-3 adrenergic receptor | Homo sapiens (human) | 4.3 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.434 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 5.279 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 6.626 | |
| Substance-K receptor | Homo sapiens (human) | 3.822 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 2.689 | |
| Thromboxane-A synthase | Homo sapiens (human) | 1.525 | |
| D(3) dopamine receptor | Homo sapiens (human) | 7.747 | |
| Delta-type opioid receptor | Homo sapiens (human) | 4.795 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 6.256 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.434 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 2.601 | |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 0.856 | |
| Leukotriene C4 synthase | Homo sapiens (human) | 5 | |
| Cysteinyl leukotriene receptor 1 | Homo sapiens (human) | 0.0015 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
2 other study(ies) available for 2-hydroxyimipramine and montelukast
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |