Page last updated: 2024-09-02
2-hydroxyimipramine and methylphenidate
2-hydroxyimipramine has been researched along with methylphenidate in 2 studies
Compound Research Comparison
Studies (2-hydroxyimipramine) | Trials (2-hydroxyimipramine) | Recent Studies (post-2010) (2-hydroxyimipramine) | Studies (methylphenidate) | Trials (methylphenidate) | Recent Studies (post-2010) (methylphenidate) |
---|---|---|---|---|---|
30 | 3 | 0 | 7,783 | 1,698 | 2,693 |
Protein Interaction Comparison
Protein | Taxonomy | 2-hydroxyimipramine (IC50) | methylphenidate (IC50) |
---|---|---|---|
Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.061 | |
Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.083 | |
Sodium-dependent serotonin transporter | Homo sapiens (human) | 5.1 | |
Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.079 |
Research
Studies (2)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Other Studies
2 other study(ies) available for 2-hydroxyimipramine and methylphenidate
Article | Year |
---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |