Page last updated: 2024-09-02

2-hydroxyimipramine and methylphenidate

2-hydroxyimipramine has been researched along with methylphenidate in 2 studies

Compound Research Comparison

Studies
(2-hydroxyimipramine)
Trials
(2-hydroxyimipramine)
Recent Studies (post-2010)
(2-hydroxyimipramine)
Studies
(methylphenidate)
Trials
(methylphenidate)
Recent Studies (post-2010) (methylphenidate)
30307,7831,6982,693

Protein Interaction Comparison

ProteinTaxonomy2-hydroxyimipramine (IC50)methylphenidate (IC50)
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.061
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.083
Sodium-dependent serotonin transporterHomo sapiens (human)5.1
Sodium-dependent dopamine transporter Homo sapiens (human)0.079

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1

Other Studies

2 other study(ies) available for 2-hydroxyimipramine and methylphenidate

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
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