2-hydroxyimipramine has been researched along with meperidine in 2 studies
| Studies (2-hydroxyimipramine) | Trials (2-hydroxyimipramine) | Recent Studies (post-2010) (2-hydroxyimipramine) | Studies (meperidine) | Trials (meperidine) | Recent Studies (post-2010) (meperidine) |
|---|---|---|---|---|---|
| 30 | 3 | 0 | 5,748 | 1,228 | 343 |
| Protein | Taxonomy | 2-hydroxyimipramine (IC50) | meperidine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.5 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.5 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.4075 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.5 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 1.435 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.5 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.5 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.3236 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
2 other study(ies) available for 2-hydroxyimipramine and meperidine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |