2-hydroxyimipramine has been researched along with domperidone in 2 studies
| Studies (2-hydroxyimipramine) | Trials (2-hydroxyimipramine) | Recent Studies (post-2010) (2-hydroxyimipramine) | Studies (domperidone) | Trials (domperidone) | Recent Studies (post-2010) (domperidone) |
|---|---|---|---|---|---|
| 30 | 3 | 0 | 1,977 | 275 | 468 |
| Protein | Taxonomy | 2-hydroxyimipramine (IC50) | domperidone (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 2 | Homo sapiens (human) | 7.9 | |
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.332 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 2.614 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 2.74 | |
| D(2) dopamine receptor | Homo sapiens (human) | 0.0026 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 2.125 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 1.011 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 2.614 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.065 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.037 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.332 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 3.055 | |
| Histamine H1 receptor | Homo sapiens (human) | 1.344 | |
| Mu-type opioid receptor | Homo sapiens (human) | 4.218 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.018 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 6.994 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 2.6 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.0052 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.1447 | |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | 2.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
2 other study(ies) available for 2-hydroxyimipramine and domperidone
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |