2-hydroxyimipramine has been researched along with diclofenac in 2 studies
| Studies (2-hydroxyimipramine) | Trials (2-hydroxyimipramine) | Recent Studies (post-2010) (2-hydroxyimipramine) | Studies (diclofenac) | Trials (diclofenac) | Recent Studies (post-2010) (diclofenac) |
|---|---|---|---|---|---|
| 30 | 3 | 0 | 8,874 | 1,874 | 3,616 |
| Protein | Taxonomy | 2-hydroxyimipramine (IC50) | diclofenac (IC50) |
|---|---|---|---|
| Aldo-keto reductase family 1 member B10 | Homo sapiens (human) | 1.9 | |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 0.003 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 1.3376 | |
| Interleukin-8 | Homo sapiens (human) | 0.008 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.0415 | |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | 0.5 | |
| C-X-C chemokine receptor type 1 | Homo sapiens (human) | 0.012 | |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | 0.5 | |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | 0.5 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.4165 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 0.5 | |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | 0.5 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 1.6867 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.0502 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 4 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 0.5 | |
| P2Y purinoceptor 12 | Rattus norvegicus (Norway rat) | 0.02 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
2 other study(ies) available for 2-hydroxyimipramine and diclofenac
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |