2-hydroxyethylvaline has been researched along with valine in 35 studies
| Studies (2-hydroxyethylvaline) | Trials (2-hydroxyethylvaline) | Recent Studies (post-2010) (2-hydroxyethylvaline) | Studies (valine) | Trials (valine) | Recent Studies (post-2010) (valine) |
|---|---|---|---|---|---|
| 39 | 1 | 6 | 15,465 | 1,176 | 3,932 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (14.29) | 18.7374 |
| 1990's | 17 (48.57) | 18.2507 |
| 2000's | 7 (20.00) | 29.6817 |
| 2010's | 4 (11.43) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Denk, B; Ehrenberg, L; Filser, JG; Kessler, W; Törnqvist, M | 1 |
| Beulink, GD; Farmer, PB; Jeffrey, AM; Magnusson, AL; Tang, YS; Törnqvist, M; van der Waal, H; van Sittert, NJ; Wazneh, L | 1 |
| Fennell, TR; MacNeela, JP; Swenberg, JA; Turner, MJ; Walker, VE | 1 |
| Törnqvist, M | 2 |
| Ehrenberg, L; Gatz, RN; Kautiainen, A; Törnqvist, M | 1 |
| Almberg, JG; Bergmark, EN; Nilsson, S; Osterman-Golkar, SM; Törnqvist, MA | 1 |
| Ehrenberg, L; Granath, F; Gustafsson, B; Harms-Ringdahl, M; Kautiainen, A; Törnqvist, M | 1 |
| Bailey, E; Brooks, AG; Farmer, PB; Passingham, BJ; Yates, DW | 1 |
| Bailey, E; Brooks, AG; Dollery, CT; Farmer, PB; Passingham, BJ; Sleightholm, MA; Yates, DW | 1 |
| Boogaard, PJ; Caubo, ME; Darroudi, F; Natarajan, AT; Tates, AD; van Sittert, NJ | 1 |
| Bailey, E; Bispo, MA; Bras, A; Farmer, PB; Palminha, J; Paz, I; Ramos, P; Rueff, J; Tavares, R | 1 |
| Fennell, TR; MacNeela, JP; Swenberg, JA; Upton, PB; Walker, VE | 1 |
| Beulink, GD; van der Waal, H; van Sittert, NJ; van Vliet, EW | 1 |
| Anderson, D; Farmer, PB; Haugen, A; Ovrebø, S | 1 |
| Bolt, HM | 1 |
| Autrup, H; Cordero, R; Farmer, PB | 1 |
| Angerer, J; Bader, M; Krämer, A | 1 |
| Ranasinghe, A; Scheller, N; Swenberg, JA; Upton, PB; Wu, KY | 1 |
| Angerer, J; Hallier, E; Krämer, A; Müller, M | 1 |
| Bono, R; Giachino, O; Meineri, V; Pignata, C; Saglia, U; Scursatone, E; Vincenti, M | 1 |
| Boogaard, PJ; Rocchi, PS; van Sittert, NJ | 1 |
| Cho, MH; Ranasinghe, A; Scheller, N; Skopek, TR; Swenberg, JA; Upton, PB; Vergnes, JS; Walker, VE; Wu, KY | 1 |
| Balkenhol, H; Bolt, HM; Dommermuth, A; Lewalter, J; Selinski, S; Thier, R | 1 |
| Angerer, J; Broding, HC; Drexler, H; Schettgen, T | 1 |
| Eckstein, A; Esser, J; Hoermann, R; Mann, K; Mueller, G; Quadbeck, B; Rettenmeier, AW; Steuhl, P | 1 |
| Bono, R; Dotti, G; Gilli, G; Pignata, C; Schilirò, T; Scursatone, E; Traversi, D; Vincenti, M | 1 |
| Chen, YL; Chiang, SY; Hsieh, CL; Huang, TH; Kuo, HW; Tseng, YS; Wu, KY | 1 |
| Ahn, HS; Shin, HS | 1 |
| Bartels, MJ; Brzak, KA; Pottenger, LH; Zhang, F | 1 |
| Bader, M; Frey, G; Nasterlack, M; Will, W | 1 |
| Boogaard, PJ; Urbanus, JH; van Puijvelde, MJ | 1 |
| Gries, W; Leng, G | 1 |
| Buchanan, S; Friedman, L; Szwiec, E | 1 |
| Bus, JS; Hays, SM; Kirman, CR; Lewis, RC; Li, AA; Sheehan, PJ | 1 |
3 review(s) available for 2-hydroxyethylvaline and valine
| Article | Year |
|---|---|
Quantification of endogenous carcinogens. The ethylene oxide paradox.
Topics: Animals; Carcinogens; DNA; Ethylene Oxide; Guanine; Hemoglobins; Humans; Valine | 1996 |
Ethylene oxide as a biological reactive intermediate of endogenous origin.
Topics: Animals; Ethylene Oxide; Hemoglobins; Humans; Neoplasms; Reactive Oxygen Species; Valine | 1996 |
Ethylene oxide review: characterization of total exposure via endogenous and exogenous pathways and their implications to risk assessment and risk management.
Topics: Animals; Environmental Exposure; Environmental Monitoring; Ethylene Oxide; Female; Humans; Male; Risk Assessment; Risk Factors; Risk Management; Valine | 2021 |
1 trial(s) available for 2-hydroxyethylvaline and valine
| Article | Year |
|---|---|
Ambient and biochemical effect monitoring of workers exposed to ethylene oxide.
Topics: Air Pollution, Indoor; Environment, Controlled; Environmental Monitoring; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Humans; Male; Occupational Exposure; Reproducibility of Results; Sensitivity and Specificity; Valine | 1998 |
31 other study(ies) available for 2-hydroxyethylvaline and valine
| Article | Year |
|---|---|
Pharmacokinetics of ethylene in man; body burden with ethylene oxide and hydroxyethylation of hemoglobin due to endogenous and environmental ethylene.
Topics: Adult; Aged; Alkylation; Body Burden; Environmental Exposure; Ethylene Oxide; Ethylenes; Female; Hemoglobins; Humans; Hydroxylation; Male; Middle Aged; Valine | 1992 |
Ring test for low levels of N-(2-hydroxyethyl)valine in human hemoglobin.
Topics: Hemoglobins; Humans; Radioimmunoassay; Regression Analysis; Valine | 1992 |
Molecular dosimetry of ethylene oxide: formation and persistence of N-(2-hydroxyethyl)valine in hemoglobin following repeated exposures of rats and mice.
Topics: Administration, Inhalation; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythrocyte Aging; Ethylene Oxide; Formamides; Globins; Hemoglobin A; Male; Mice; Mice, Inbred C3H; Rats; Rats, Inbred F344; Valine | 1992 |
Formation of reactive species that lead to hemoglobin adducts during storage of blood samples.
Topics: Alkylation; Blood Preservation; Cell Separation; Erythrocytes; Ethylene Oxide; Freeze Drying; Globins; Hemoglobins; Hemolysis; Histidine; Humans; Valine | 1990 |
Hemoglobin adducts in animals exposed to gasoline and diesel exhausts. 1. Alkenes.
Topics: Alkenes; Animals; Calibration; Cricetinae; Dose-Response Relationship, Drug; Ethylenes; Female; Gas Chromatography-Mass Spectrometry; Gasoline; Globins; Hemoglobins; Male; Mesocricetus; Mutagens; Rats; Rats, Inbred F344; Risk Factors; Sex Factors; Species Specificity; Valine; Vehicle Emissions | 1988 |
Ethylene oxide doses in ethene-exposed fruit store workers.
Topics: Air Pollutants, Occupational; Ethylene Oxide; Ethylenes; Food Handling; Fruit; Hemoglobins; Humans; Valine | 1989 |
Unsaturated lipids and intestinal bacteria as sources of endogenous production of ethene and ethylene oxide.
Topics: Animals; Dietary Fats; Ethylene Oxide; Ethylenes; Fatty Acids, Unsaturated; Intestinal Mucosa; Intestines; Lipid Peroxides; Male; Mice; Mice, Inbred CBA; Valine | 1989 |
2-Hydroxyethylation of haemoglobin in man.
Topics: Cotinine; Gas Chromatography-Mass Spectrometry; Hemoglobins; Histidine; Humans; Smoking; Valine | 1988 |
Hydroxyethylvaline adduct formation in haemoglobin as a biological monitor of cigarette smoke intake.
Topics: Biomarkers; Cotinine; Ethylene Oxide; Hemoglobins; Humans; Nicotiana; Plants, Toxic; Smoke; Valine | 1988 |
Biological effect monitoring in industrial workers following incidental exposure to high concentrations of ethylene oxide.
Topics: Accidents, Occupational; Adult; Case-Control Studies; Chemical Industry; DNA Adducts; Environmental Monitoring; Erythrocytes; Ethylene Oxide; Hemoglobins; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Micronuclei, Chromosome-Defective; Middle Aged; Mutation; Netherlands; Occupational Exposure; Sister Chromatid Exchange; Valine | 1995 |
Transplacental exposure to genotoxins. Evaluation in haemoglobin of hydroxyethylvaline adduct levels in smoking and non-smoking mothers and their newborns.
Topics: Carcinogens; Female; Fetus; Hemoglobins; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Smoking; Valine | 1994 |
Molecular dosimetry of DNA and hemoglobin adducts in mice and rats exposed to ethylene oxide.
Topics: Animals; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethylene Oxide; Guanine; Hemoglobins; Male; Mice; Rats; Rats, Inbred F344; Time Factors; Valine | 1993 |
Monitoring occupational exposure to ethylene oxide by the determination of hemoglobin adducts.
Topics: Chemical Industry; Environmental Monitoring; Ethylene Oxide; Hemoglobins; Humans; Occupational Exposure; Valine | 1993 |
Evaluation of biomarkers in plasma, blood, and urine samples from coke oven workers: significance of exposure to polycyclic aromatic hydrocarbons.
Topics: Adult; Antibodies; Benzo(a)pyrene; Biomarkers; Carcinogens, Environmental; Case-Control Studies; Coke; DNA Adducts; Environmental Monitoring; Enzyme-Linked Immunosorbent Assay; Humans; Middle Aged; Mutagens; Occupational Exposure; Polycyclic Aromatic Hydrocarbons; Pyrenes; Valine | 1995 |
Monitoring human exposure to 2-hydroxyethylating carcinogens.
Topics: Adult; Carcinogens, Environmental; Cohort Studies; Environmental Exposure; Female; Fetal Blood; Gas Chromatography-Mass Spectrometry; Genotype; Glutathione Transferase; Hemoglobins; Humans; Pregnancy; Smoking; Valine | 1996 |
Application of gas chromatography/electron capture negative chemical ionization high-resolution mass spectrometry for analysis of DNA and protein adducts.
Topics: Animals; Calibration; DNA Adducts; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Indicators and Reagents; Proteins; Rats; Valine | 1998 |
Ethylene oxide-protein adduct formation in humans: influence of glutathione-S-transferase polymorphisms.
Topics: Case-Control Studies; DNA Adducts; Environmental Exposure; Ethylene Oxide; Female; Genotype; Glutathione Transferase; Humans; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Smoking; Statistics, Nonparametric; Substrate Specificity; Surveys and Questionnaires; Valine | 1998 |
Formation of N-(2-hydroxyethyl)valine due to exposure to ethylene oxide via tobacco smoke: A risk factor for onset of cancer.
Topics: Adolescent; Adult; Biomarkers; Carcinogens; Cotinine; Ethylene Oxide; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Male; Risk Factors; Smoking; Surveys and Questionnaires; Tobacco Smoke Pollution; Urban Population; Valine | 1999 |
Biomonitoring of exposure to ethylene oxide and propylene oxide by determination of hemoglobin adducts: correlations between airborne exposure and adduct levels.
Topics: Air Pollutants, Occupational; Biomarkers; Carcinogens; Chromatography, Gas; Environmental Monitoring; Epoxy Compounds; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Male; Occupational Exposure; Valine | 1999 |
Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide.
Topics: Animals; Biomarkers; Biotransformation; Carcinogens; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethylene Oxide; Ethylenes; Guanine; Hemoglobins; Hypoxanthine Phosphoribosyltransferase; Inhalation Exposure; Male; Mice; Mice, Inbred Strains; Mutation; Rats; Rats, Inbred F344; T-Lymphocytes; Valine | 2000 |
Influence of polymorphisms of the human glutathione transferases and cytochrome P450 2E1 enzyme on the metabolism and toxicity of ethylene oxide and acrylonitrile.
Topics: Acrylonitrile; Carcinogens; Cytochrome P-450 CYP2E1; DNA Adducts; Ethylene Oxide; Glutathione S-Transferase pi; Glutathione Transferase; Hemoglobins; Humans; Isoenzymes; Occupational Exposure; Polymorphism, Genetic; Valine | 2001 |
Hemoglobin adducts of ethylene oxide, propylene oxide, acrylonitrile and acrylamide-biomarkers in occupational and environmental medicine.
Topics: Acrylamide; Acrylonitrile; Adult; Biomarkers; Diet; Epoxy Compounds; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Middle Aged; Occupational Exposure; Smoking; Valine | 2002 |
Impact of smoking on the response to treatment of thyroid associated ophthalmopathy.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Combined Modality Therapy; Female; Fludrocortisone; Graves Disease; Hemoglobins; Humans; Male; Middle Aged; Ocular Motility Disorders; Prospective Studies; Smoking; Treatment Outcome; Valine | 2003 |
Cotinine and N-(2-hydroxyethyl)valine as markers of passive exposure to tobacco smoke in children.
Topics: Adolescent; Biomarkers; Child; Child, Preschool; Cotinine; Environmental Exposure; Female; Humans; Male; Reference Values; Sensitivity and Specificity; Tobacco Smoke Pollution; Valine | 2005 |
Formation of N-(2-hydroxyethyl)valine in human hemoglobin-effect of lifestyle factors.
Topics: Adult; Age Factors; Alcohol Drinking; Analysis of Variance; Biomarkers; Ethylene Oxide; Ethylenes; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Life Style; Male; Risk Factors; Sex Factors; Smoking; Taiwan; Tea; Valine | 2004 |
Determination of ethylene oxide-hemoglobin adduct by silylation and gas chromatography-electron impact-mass spectrometry.
Topics: Biomarkers; Environmental Exposure; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Reproducibility of Results; Trimethylsilyl Compounds; Valine | 2006 |
Direct quantitation of hydroxyethylvaline in hemoglobin by liquid chromatography/positive electrospray tandem mass spectrometry.
Topics: Animals; Chromatography, Liquid; Ethylenes; Hemoglobins; Hydrolysis; Male; Rats; Rats, Inbred F344; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Valine | 2012 |
Analysis of protein adducts as biomarkers of short-term exposure to ethylene oxide and results of follow-up biomonitoring.
Topics: Accidents, Occupational; Biomarkers; Carcinogens; Chemical Industry; Cotinine; Ethylene Oxide; Humans; Male; Occupational Exposure; Smoking; Valine | 2012 |
Biological monitoring to assess dermal exposure to ethylene oxide vapours during an incidental release.
Topics: Adult; Chemical Hazard Release; Environmental Monitoring; Ethylene Oxide; Humans; Male; Models, Biological; Netherlands; Occupational Exposure; Skin Absorption; Valine | 2014 |
Biomonitoring following a chemical incident with acrylonitrile and ethylene in 2008.
Topics: Accidents, Occupational; Acrylonitrile; Chemical Hazard Release; Emergency Responders; Environmental Monitoring; Ethylenes; Firefighters; Germany; Hemoglobins; Humans; Occupational Exposure; Police; Valine | 2014 |
Levels of Ethylene Oxide Biomarker in an Exposed Residential Community.
Topics: Adolescent; Adult; Aged; Biomarkers; Carcinogens; Child; Child, Preschool; Cotinine; Environmental Exposure; Ethylene Oxide; Female; Hemoglobin A; Hemoglobins; Humans; Infant; Infant, Newborn; Male; Middle Aged; North Carolina; Public Health Surveillance; Residence Characteristics; Smoking; Surveys and Questionnaires; Valine; Young Adult | 2020 |