Page last updated: 2024-09-02

2-hydroxyethylvaline and ethylene oxide

2-hydroxyethylvaline has been researched along with ethylene oxide in 24 studies

Compound Research Comparison

Studies
(2-hydroxyethylvaline)
Trials
(2-hydroxyethylvaline)
Recent Studies (post-2010)
(2-hydroxyethylvaline)
Studies
(ethylene oxide)
Trials
(ethylene oxide)
Recent Studies (post-2010) (ethylene oxide)
39162,96720432

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.50)18.7374
1990's12 (50.00)18.2507
2000's5 (20.83)29.6817
2010's2 (8.33)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Denk, B; Ehrenberg, L; Filser, JG; Kessler, W; Törnqvist, M1
Fennell, TR; MacNeela, JP; Swenberg, JA; Turner, MJ; Walker, VE1
Törnqvist, M2
Almberg, JG; Bergmark, EN; Nilsson, S; Osterman-Golkar, SM; Törnqvist, MA1
Ehrenberg, L; Granath, F; Gustafsson, B; Harms-Ringdahl, M; Kautiainen, A; Törnqvist, M1
Bailey, E; Brooks, AG; Dollery, CT; Farmer, PB; Passingham, BJ; Sleightholm, MA; Yates, DW1
Boogaard, PJ; Caubo, ME; Darroudi, F; Natarajan, AT; Tates, AD; van Sittert, NJ1
Fennell, TR; MacNeela, JP; Swenberg, JA; Upton, PB; Walker, VE1
Beulink, GD; van der Waal, H; van Sittert, NJ; van Vliet, EW1
Bolt, HM1
Angerer, J; Bader, M; Krämer, A1
Angerer, J; Hallier, E; Krämer, A; Müller, M1
Bono, R; Giachino, O; Meineri, V; Pignata, C; Saglia, U; Scursatone, E; Vincenti, M1
Boogaard, PJ; Rocchi, PS; van Sittert, NJ1
Cho, MH; Ranasinghe, A; Scheller, N; Skopek, TR; Swenberg, JA; Upton, PB; Vergnes, JS; Walker, VE; Wu, KY1
Balkenhol, H; Bolt, HM; Dommermuth, A; Lewalter, J; Selinski, S; Thier, R1
Angerer, J; Broding, HC; Drexler, H; Schettgen, T1
Chen, YL; Chiang, SY; Hsieh, CL; Huang, TH; Kuo, HW; Tseng, YS; Wu, KY1
Ahn, HS; Shin, HS1
Bader, M; Frey, G; Nasterlack, M; Will, W1
Boogaard, PJ; Urbanus, JH; van Puijvelde, MJ1
Buchanan, S; Friedman, L; Szwiec, E1
Bus, JS; Hays, SM; Kirman, CR; Lewis, RC; Li, AA; Sheehan, PJ1

Reviews

3 review(s) available for 2-hydroxyethylvaline and ethylene oxide

ArticleYear
Quantification of endogenous carcinogens. The ethylene oxide paradox.
    Biochemical pharmacology, 1996, Jul-12, Volume: 52, Issue:1

    Topics: Animals; Carcinogens; DNA; Ethylene Oxide; Guanine; Hemoglobins; Humans; Valine

1996
Ethylene oxide as a biological reactive intermediate of endogenous origin.
    Advances in experimental medicine and biology, 1996, Volume: 387

    Topics: Animals; Ethylene Oxide; Hemoglobins; Humans; Neoplasms; Reactive Oxygen Species; Valine

1996
Ethylene oxide review: characterization of total exposure via endogenous and exogenous pathways and their implications to risk assessment and risk management.
    Journal of toxicology and environmental health. Part B, Critical reviews, 2021, 01-02, Volume: 24, Issue:1

    Topics: Animals; Environmental Exposure; Environmental Monitoring; Ethylene Oxide; Female; Humans; Male; Risk Assessment; Risk Factors; Risk Management; Valine

2021

Trials

1 trial(s) available for 2-hydroxyethylvaline and ethylene oxide

ArticleYear
Ambient and biochemical effect monitoring of workers exposed to ethylene oxide.
    International archives of occupational and environmental health, 1998, Volume: 71, Issue:1

    Topics: Air Pollution, Indoor; Environment, Controlled; Environmental Monitoring; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Humans; Male; Occupational Exposure; Reproducibility of Results; Sensitivity and Specificity; Valine

1998

Other Studies

20 other study(ies) available for 2-hydroxyethylvaline and ethylene oxide

ArticleYear
Pharmacokinetics of ethylene in man; body burden with ethylene oxide and hydroxyethylation of hemoglobin due to endogenous and environmental ethylene.
    Archives of toxicology, 1992, Volume: 66, Issue:3

    Topics: Adult; Aged; Alkylation; Body Burden; Environmental Exposure; Ethylene Oxide; Ethylenes; Female; Hemoglobins; Humans; Hydroxylation; Male; Middle Aged; Valine

1992
Molecular dosimetry of ethylene oxide: formation and persistence of N-(2-hydroxyethyl)valine in hemoglobin following repeated exposures of rats and mice.
    Cancer research, 1992, Aug-15, Volume: 52, Issue:16

    Topics: Administration, Inhalation; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Erythrocyte Aging; Ethylene Oxide; Formamides; Globins; Hemoglobin A; Male; Mice; Mice, Inbred C3H; Rats; Rats, Inbred F344; Valine

1992
Formation of reactive species that lead to hemoglobin adducts during storage of blood samples.
    Carcinogenesis, 1990, Volume: 11, Issue:1

    Topics: Alkylation; Blood Preservation; Cell Separation; Erythrocytes; Ethylene Oxide; Freeze Drying; Globins; Hemoglobins; Hemolysis; Histidine; Humans; Valine

1990
Ethylene oxide doses in ethene-exposed fruit store workers.
    Scandinavian journal of work, environment & health, 1989, Volume: 15, Issue:6

    Topics: Air Pollutants, Occupational; Ethylene Oxide; Ethylenes; Food Handling; Fruit; Hemoglobins; Humans; Valine

1989
Unsaturated lipids and intestinal bacteria as sources of endogenous production of ethene and ethylene oxide.
    Carcinogenesis, 1989, Volume: 10, Issue:1

    Topics: Animals; Dietary Fats; Ethylene Oxide; Ethylenes; Fatty Acids, Unsaturated; Intestinal Mucosa; Intestines; Lipid Peroxides; Male; Mice; Mice, Inbred CBA; Valine

1989
Hydroxyethylvaline adduct formation in haemoglobin as a biological monitor of cigarette smoke intake.
    Archives of toxicology, 1988, Volume: 62, Issue:4

    Topics: Biomarkers; Cotinine; Ethylene Oxide; Hemoglobins; Humans; Nicotiana; Plants, Toxic; Smoke; Valine

1988
Biological effect monitoring in industrial workers following incidental exposure to high concentrations of ethylene oxide.
    Mutation research, 1995, Volume: 329, Issue:1

    Topics: Accidents, Occupational; Adult; Case-Control Studies; Chemical Industry; DNA Adducts; Environmental Monitoring; Erythrocytes; Ethylene Oxide; Hemoglobins; Humans; Hypoxanthine Phosphoribosyltransferase; Lymphocytes; Micronuclei, Chromosome-Defective; Middle Aged; Mutation; Netherlands; Occupational Exposure; Sister Chromatid Exchange; Valine

1995
Molecular dosimetry of DNA and hemoglobin adducts in mice and rats exposed to ethylene oxide.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Animals; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethylene Oxide; Guanine; Hemoglobins; Male; Mice; Rats; Rats, Inbred F344; Time Factors; Valine

1993
Monitoring occupational exposure to ethylene oxide by the determination of hemoglobin adducts.
    Environmental health perspectives, 1993, Volume: 99

    Topics: Chemical Industry; Environmental Monitoring; Ethylene Oxide; Hemoglobins; Humans; Occupational Exposure; Valine

1993
Ethylene oxide-protein adduct formation in humans: influence of glutathione-S-transferase polymorphisms.
    International archives of occupational and environmental health, 1998, Volume: 71, Issue:7

    Topics: Case-Control Studies; DNA Adducts; Environmental Exposure; Ethylene Oxide; Female; Genotype; Glutathione Transferase; Humans; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Smoking; Statistics, Nonparametric; Substrate Specificity; Surveys and Questionnaires; Valine

1998
Formation of N-(2-hydroxyethyl)valine due to exposure to ethylene oxide via tobacco smoke: A risk factor for onset of cancer.
    Environmental research, 1999, Volume: 81, Issue:1

    Topics: Adolescent; Adult; Biomarkers; Carcinogens; Cotinine; Ethylene Oxide; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Male; Risk Factors; Smoking; Surveys and Questionnaires; Tobacco Smoke Pollution; Urban Population; Valine

1999
Biomonitoring of exposure to ethylene oxide and propylene oxide by determination of hemoglobin adducts: correlations between airborne exposure and adduct levels.
    International archives of occupational and environmental health, 1999, Volume: 72, Issue:3

    Topics: Air Pollutants, Occupational; Biomarkers; Carcinogens; Chromatography, Gas; Environmental Monitoring; Epoxy Compounds; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Male; Occupational Exposure; Valine

1999
Biomarkers of exposure and effect as indicators of potential carcinogenic risk arising from in vivo metabolism of ethylene to ethylene oxide.
    Carcinogenesis, 2000, Volume: 21, Issue:9

    Topics: Animals; Biomarkers; Biotransformation; Carcinogens; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethylene Oxide; Ethylenes; Guanine; Hemoglobins; Hypoxanthine Phosphoribosyltransferase; Inhalation Exposure; Male; Mice; Mice, Inbred Strains; Mutation; Rats; Rats, Inbred F344; T-Lymphocytes; Valine

2000
Influence of polymorphisms of the human glutathione transferases and cytochrome P450 2E1 enzyme on the metabolism and toxicity of ethylene oxide and acrylonitrile.
    Mutation research, 2001, Oct-01, Volume: 482, Issue:1-2

    Topics: Acrylonitrile; Carcinogens; Cytochrome P-450 CYP2E1; DNA Adducts; Ethylene Oxide; Glutathione S-Transferase pi; Glutathione Transferase; Hemoglobins; Humans; Isoenzymes; Occupational Exposure; Polymorphism, Genetic; Valine

2001
Hemoglobin adducts of ethylene oxide, propylene oxide, acrylonitrile and acrylamide-biomarkers in occupational and environmental medicine.
    Toxicology letters, 2002, Aug-05, Volume: 134, Issue:1-3

    Topics: Acrylamide; Acrylonitrile; Adult; Biomarkers; Diet; Epoxy Compounds; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Middle Aged; Occupational Exposure; Smoking; Valine

2002
Formation of N-(2-hydroxyethyl)valine in human hemoglobin-effect of lifestyle factors.
    Mutation research, 2004, Apr-11, Volume: 559, Issue:1-2

    Topics: Adult; Age Factors; Alcohol Drinking; Analysis of Variance; Biomarkers; Ethylene Oxide; Ethylenes; Female; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Life Style; Male; Risk Factors; Sex Factors; Smoking; Taiwan; Tea; Valine

2004
Determination of ethylene oxide-hemoglobin adduct by silylation and gas chromatography-electron impact-mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Nov-07, Volume: 843, Issue:2

    Topics: Biomarkers; Environmental Exposure; Ethylene Oxide; Gas Chromatography-Mass Spectrometry; Hemoglobins; Humans; Reproducibility of Results; Trimethylsilyl Compounds; Valine

2006
Analysis of protein adducts as biomarkers of short-term exposure to ethylene oxide and results of follow-up biomonitoring.
    Arhiv za higijenu rada i toksikologiju, 2012, Jun-01, Volume: 63, Issue:2

    Topics: Accidents, Occupational; Biomarkers; Carcinogens; Chemical Industry; Cotinine; Ethylene Oxide; Humans; Male; Occupational Exposure; Smoking; Valine

2012
Biological monitoring to assess dermal exposure to ethylene oxide vapours during an incidental release.
    Toxicology letters, 2014, Dec-15, Volume: 231, Issue:3

    Topics: Adult; Chemical Hazard Release; Environmental Monitoring; Ethylene Oxide; Humans; Male; Models, Biological; Netherlands; Occupational Exposure; Skin Absorption; Valine

2014
Levels of Ethylene Oxide Biomarker in an Exposed Residential Community.
    International journal of environmental research and public health, 2020, 11-21, Volume: 17, Issue:22

    Topics: Adolescent; Adult; Aged; Biomarkers; Carcinogens; Child; Child, Preschool; Cotinine; Environmental Exposure; Ethylene Oxide; Female; Hemoglobin A; Hemoglobins; Humans; Infant; Infant, Newborn; Male; Middle Aged; North Carolina; Public Health Surveillance; Residence Characteristics; Smoking; Surveys and Questionnaires; Valine; Young Adult

2020