2-hydroxyestradiol has been researched along with 2-fluoroestradiol* in 1 studies
1 other study(ies) available for 2-hydroxyestradiol and 2-fluoroestradiol
| Article | Year |
|---|---|
Novel synthesis of 2-fluoroestradiol from 19-nortestosterone: biomimetic oxidative defluorination to 2-hydroxyestradiol.
A new, short synthetic route to 2-fluoroestradiol from 19-nortestosterone is described which gives the target compound in an approximately 25% overall yield. Oxidative defluorination of 2-fluoroestradiol to 2-hydroxyestradiol via treatment with Frémy's salt/iodide ion is reported. This process is regarded as biomimetic with respect to cytochrome P-450-dependent oxidative defluorination. Topics: Chemical Phenomena; Chemistry; Estradiol; Estrogens; Estrogens, Catechol; Magnetic Resonance Spectroscopy; Molecular Structure; Nandrolone | 1989 |