Compounds > 2-hydroxy-5-nitrobenzylthioguanosine
Page last updated: 2024-09-04

2-hydroxy-5-nitrobenzylthioguanosine and indomethacin

2-hydroxy-5-nitrobenzylthioguanosine has been researched along with indomethacin in 3 studies

Compound Research Comparison

Studies
(2-hydroxy-5-nitrobenzylthioguanosine)		Trials
(2-hydroxy-5-nitrobenzylthioguanosine)		Recent Studies (post-2010)
(2-hydroxy-5-nitrobenzylthioguanosine)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
110029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomy2-hydroxy-5-nitrobenzylthioguanosine (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baer, HP; Clanachan, AS; Naughton, P; Scott, GW1
Frew, R; Lundy, PM1
Castagliuolo, I; Matthews, JB; Pothoulakis, C; Riegler, M; Sogukoglu, T; Wang, C; Wenzl, E; Wlk, M1

Other Studies

3 other study(ies) available for 2-hydroxy-5-nitrobenzylthioguanosine and indomethacin

ArticleYear
Adenosine and ATP effects on isolated guinea pig gallbladder.
    Pflugers Archiv : European journal of physiology, 1983, Volume: 399, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Animals; Culture Techniques; Drug Interactions; Gallbladder; Guanosine; Guinea Pigs; Indomethacin; Muscle Contraction; Muscle, Smooth; Theophylline; Thionucleosides

1983
Effect of arylazido aminopropionyl ATP (ANAPP3), on ATP responses of isolated guinea pig smooth muscle.
    Life sciences, 1982, Jan-18, Volume: 30, Issue:3

    Topics: Adenosine Triphosphate; Animals; Azides; Guanosine; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth; Norepinephrine; Stomach; Thionucleosides; Vas Deferens

1982
Neurotensin stimulates Cl(-) secretion in human colonic mucosa In vitro: role of adenosine.
    Gastroenterology, 2000, Volume: 119, Issue:2

    Topics: Adamantane; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Chlorides; Colon; Electrophysiology; Enteric Nervous System; Enzyme Inhibitors; Guanosine; Histamine; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Mast Cells; Membrane Potentials; Neurotensin; Pentostatin; Pyrazoles; Quinolines; Receptors, Neurotensin; Tetrodotoxin; Thioinosine; Thionucleosides

2000