Compounds > 2-hydroxy-5-nitrobenzylthioguanosine
Page last updated: 2024-09-04

2-hydroxy-5-nitrobenzylthioguanosine and dipyridamole

2-hydroxy-5-nitrobenzylthioguanosine has been researched along with dipyridamole in 3 studies

Compound Research Comparison

Studies
(2-hydroxy-5-nitrobenzylthioguanosine)		Trials
(2-hydroxy-5-nitrobenzylthioguanosine)		Recent Studies (post-2010)
(2-hydroxy-5-nitrobenzylthioguanosine)		Studies
(dipyridamole)		Trials
(dipyridamole)		Recent Studies (post-2010) (dipyridamole)
11007,826881632

Protein Interaction Comparison

ProteinTaxonomy2-hydroxy-5-nitrobenzylthioguanosine (IC50)dipyridamole (IC50)
90-kda heat shock protein beta HSP90 beta, partialHomo sapiens (human)21.0682
heat shock protein HSP 90-alpha isoform 2Homo sapiens (human)21.0682
cGMP-dependent 3',5'-cyclic phosphodiesteraseHomo sapiens (human)3.1233
Solute carrier family 22 member 2Homo sapiens (human)2.6
Multidrug resistance-associated protein 4Homo sapiens (human)5.15
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8AHomo sapiens (human)2.6333
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)1.9708
3',5'-cyclic-AMP phosphodiesterase Sus scrofa (pig)5.835
Bile salt export pumpHomo sapiens (human)4
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)6.956
cAMP-specific 3',5'-cyclic phosphodiesterase 4AHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4BHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4CHomo sapiens (human)0.5
cAMP-specific 3',5'-cyclic phosphodiesterase 4DHomo sapiens (human)2.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase AHomo sapiens (human)2.6333
Exopolyphosphatase PRUNE1Homo sapiens (human)0.78
Equilibrative nucleoside transporter 1Homo sapiens (human)0.0537
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)6.4

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baer, HP; Burnstock, G; Frew, R1
Hughes, JM; Tattersall, MH1
Camarasa, J; Camins, A; Escubedo, E; Jiménez, A; Lladó, S; Pallàs, M; Pubill, D1

Other Studies

3 other study(ies) available for 2-hydroxy-5-nitrobenzylthioguanosine and dipyridamole

ArticleYear
Effect of dipyridamole and 6-(2-hydroxy-5-nitro)-benzylthioguanosine on low-frequency-stimulated relaxation in the guinea pig taenia coli.
    Canadian journal of physiology and pharmacology, 1977, Volume: 55, Issue:3

    Topics: Adenosine; Animals; Colon; Dipyridamole; Electric Stimulation; Female; Guanosine; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Thionucleosides

1977
Potentiation of methotrexate lymphocytotoxicity in vitro by inhibitors of nucleoside transport.
    British journal of cancer, 1989, Volume: 59, Issue:3

    Topics: Cell Survival; Cells, Cultured; Dipyridamole; Drug Synergism; Guanosine; Humans; Lymphocytes; Methotrexate; Thionucleosides

1989
Further characterization of an adenosine transport system in the mitochondrial fraction of rat testis.
    European journal of pharmacology, 2000, Jun-09, Volume: 398, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzodiazepinones; Biological Transport; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Guanosine; Hexobendine; Hydrogen-Ion Concentration; Inosine; Isoquinolines; Kinetics; Male; Mitochondria; Osmolar Concentration; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Sodium; Subcellular Fractions; Temperature; Testis; Thioinosine; Thionucleosides; Time Factors; Tritium; Uridine

2000