Page last updated: 2024-09-04

2-hydroxy-5-nitrobenzylthioguanosine and 4-nitrobenzylthioinosine

2-hydroxy-5-nitrobenzylthioguanosine has been researched along with 4-nitrobenzylthioinosine in 5 studies

Compound Research Comparison

Studies
(2-hydroxy-5-nitrobenzylthioguanosine)
Trials
(2-hydroxy-5-nitrobenzylthioguanosine)
Recent Studies (post-2010)
(2-hydroxy-5-nitrobenzylthioguanosine)
Studies
(4-nitrobenzylthioinosine)
Trials
(4-nitrobenzylthioinosine)
Recent Studies (post-2010) (4-nitrobenzylthioinosine)
1100666257

Protein Interaction Comparison

ProteinTaxonomy2-hydroxy-5-nitrobenzylthioguanosine (IC50)4-nitrobenzylthioinosine (IC50)
Equilibrative nucleoside transporter 1Homo sapiens (human)0.0043

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buolamwini, JK; Zhu, Z1
Cass, CE; Gati, WP; Odegard, R; Paterson, AR1
Crawley, JN; Marangos, PJ; Patel, J1
Camarasa, J; Camins, A; Escubedo, E; Jiménez, A; Lladó, S; Pallàs, M; Pubill, D1
Castagliuolo, I; Matthews, JB; Pothoulakis, C; Riegler, M; Sogukoglu, T; Wang, C; Wenzl, E; Wlk, M1

Other Studies

5 other study(ies) available for 2-hydroxy-5-nitrobenzylthioguanosine and 4-nitrobenzylthioinosine

ArticleYear
Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity.
    Bioorganic & medicinal chemistry, 2008, Apr-01, Volume: 16, Issue:7

    Topics: Drug Design; Equilibrative Nucleoside Transporter 1; Glycosides; Humans; K562 Cells; Models, Biological; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Static Electricity; Thioinosine

2008
The effect of pH on interaction of nitrobenzylthioinosine and hydroxynitrobenzylthioinosine with the nucleoside transporter of human erythrocyte membranes.
    Molecular pharmacology, 1985, Volume: 27, Issue:6

    Topics: Affinity Labels; Binding, Competitive; Blood Proteins; Carrier Proteins; Erythrocyte Membrane; Guanosine; Humans; Hydrogen-Ion Concentration; Inosine; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Thioinosine; Thionucleosides

1985
Adenosine uptake inhibitors potentiate the sedative effects of adenosine.
    Neuroscience letters, 1983, Apr-11, Volume: 36, Issue:2

    Topics: Adenosine; Animals; Arousal; Brain; Guanosine; Inosine; Male; Mice; Mice, Inbred C57BL; Motor Activity; Receptors, Cell Surface; Receptors, Purinergic; Synapses; Thioinosine; Thionucleosides

1983
Further characterization of an adenosine transport system in the mitochondrial fraction of rat testis.
    European journal of pharmacology, 2000, Jun-09, Volume: 398, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzodiazepinones; Biological Transport; Dilazep; Dipyridamole; Dose-Response Relationship, Drug; Guanosine; Hexobendine; Hydrogen-Ion Concentration; Inosine; Isoquinolines; Kinetics; Male; Mitochondria; Osmolar Concentration; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Sodium; Subcellular Fractions; Temperature; Testis; Thioinosine; Thionucleosides; Time Factors; Tritium; Uridine

2000
Neurotensin stimulates Cl(-) secretion in human colonic mucosa In vitro: role of adenosine.
    Gastroenterology, 2000, Volume: 119, Issue:2

    Topics: Adamantane; Adenosine; Adenosine Deaminase Inhibitors; Affinity Labels; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Chlorides; Colon; Electrophysiology; Enteric Nervous System; Enzyme Inhibitors; Guanosine; Histamine; Humans; Imidazoles; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Mast Cells; Membrane Potentials; Neurotensin; Pentostatin; Pyrazoles; Quinolines; Receptors, Neurotensin; Tetrodotoxin; Thioinosine; Thionucleosides

2000