Page last updated: 2024-09-05

2-hexynyladenosine-5'-n-ethylcarboxamide and phenylisopropyladenosine

2-hexynyladenosine-5'-n-ethylcarboxamide has been researched along with phenylisopropyladenosine in 4 studies

Compound Research Comparison

Studies
(2-hexynyladenosine-5'-n-ethylcarboxamide)
Trials
(2-hexynyladenosine-5'-n-ethylcarboxamide)
Recent Studies (post-2010)
(2-hexynyladenosine-5'-n-ethylcarboxamide)
Studies
(phenylisopropyladenosine)
Trials
(phenylisopropyladenosine)
Recent Studies (post-2010) (phenylisopropyladenosine)
280263010

Protein Interaction Comparison

ProteinTaxonomy2-hexynyladenosine-5'-n-ethylcarboxamide (IC50)phenylisopropyladenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)1.8613
Adenosine receptor A1Rattus norvegicus (Norway rat)0.0294
Adenosine receptor A3Rattus norvegicus (Norway rat)0.0497
Adenosine receptor A2bRattus norvegicus (Norway rat)0.2898
Adenosine receptor A1Homo sapiens (human)0.83
Adenosine receptor A2aRattus norvegicus (Norway rat)0.2898

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cristalli, G; Eleuteri, A; Klotz, KN; Lohse, MJ; Vittori, S; Volpini, R1
Arslan, G; Dionisotti, S; Fredholm, BB; Kull, B; Ongini, E; Zocchi, C1
Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U1
Baraldi, PG; Benini, A; Borea, PA; Cattabriga, E; Gessi, S; Klotz, KN; Lennan, SM; Leung, E; Merighi, S; Tabrizi, MA; Varani, K; Vincenzi, F1

Other Studies

4 other study(ies) available for 2-hexynyladenosine-5'-n-ethylcarboxamide and phenylisopropyladenosine

ArticleYear
2-Alkynyl derivatives of adenosine and adenosine-5'-N-ethyluronamide as selective agonists at A2 adenosine receptors.
    Journal of medicinal chemistry, 1992, Jun-26, Volume: 35, Issue:13

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Binding, Competitive; Blood Platelets; Brain Chemistry; Cell Membrane; Cells, Cultured; Humans; Platelet Aggregation; Radioligand Assay; Rats; Receptors, Purinergic

1992
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261.
    British journal of pharmacology, 1997, Volume: 121, Issue:3

    Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Species Specificity; Transfection; Triazoles

1997
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.
    Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium

1999
Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors.
    Biochemical pharmacology, 2005, Nov-25, Volume: 70, Issue:11

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Binding, Competitive; Cell Line; Cyclic AMP; Humans; Molecular Structure; Protein Binding; Receptor, Adenosine A2B; Recombinant Proteins

2005