2-hexynyladenosine-5'-n-ethylcarboxamide has been researched along with adenosine in 13 studies
| Studies (2-hexynyladenosine-5'-n-ethylcarboxamide) | Trials (2-hexynyladenosine-5'-n-ethylcarboxamide) | Recent Studies (post-2010) (2-hexynyladenosine-5'-n-ethylcarboxamide) | Studies (adenosine) | Trials (adenosine) | Recent Studies (post-2010) (adenosine) |
|---|---|---|---|---|---|
| 28 | 0 | 2 | 32,536 | 1,075 | 8,930 |
| Protein | Taxonomy | 2-hexynyladenosine-5'-n-ethylcarboxamide (IC50) | adenosine (IC50) |
|---|---|---|---|
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | 0.3851 | |
| Sodium/nucleoside cotransporter 1 | Homo sapiens (human) | 5.5 | |
| Sodium/nucleoside cotransporter 2 | Homo sapiens (human) | 5.5 | |
| Adenosine receptor A3 | Homo sapiens (human) | 0.0011 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.0023 | |
| Equilibrative nucleoside transporter 1 | Homo sapiens (human) | 63 | |
| Solute carrier family 28 member 3 | Homo sapiens (human) | 3.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (92.31) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cristalli, G; Esker, JL; Jacobson, KA; Ji, XD; Melman, N; Olah, ME; Schneller, SW; Secrist, JA; Siddiqi, SM; Tiwari, KN | 1 |
| Bonizzoni, E; Casati, C; Milani, S; Monopoli, A; Ongini, E | 1 |
| Casati, C; Conti, A; Cristalli, G; Monopoli, A; Ongini, E; Volpini, R; Zocchi, C | 1 |
| Chintala, M; Chiu, PJ; Dionisotti, S; Ongini, E; Sandoli, D | 1 |
| Bonizzoni, E; Casati, C; Dionisotti, S; Monopoli, A; Ongini, E; Zocchi, C | 1 |
| Busca, G; Castoldi, G; Genovesi, S; Golin, R; Panzacchi, G; Protasoni, G; Stella, A | 1 |
| Conti, A; Lozza, G; Monopoli, A | 1 |
| Cristalli, G; Morelli, M; Pinna, A; Wardas, J | 1 |
| Alberti, C; Casati, C; Forlani, A; Monopoli, A; Morganti, A; Nador, B; Ongini, E; Sala, C | 1 |
| Constantino, MD; Cunha, RA; Ribeiro, JA | 1 |
| Busca, G; Demarchi, B; Golin, R; Panzacchi, G; Protasoni, G; Stella, A | 1 |
| Camisasca, P; Genovesi, S; Golin, R; Pieruzzi, F; Protasoni, G; Ragonesi, G; Stella, A; Zanchetti, A | 1 |
| Alberti, C; Casati, C; Monopoli, A; Morganti, A; Ongini, E; Sala, C; Zanchetti, A | 1 |
13 other study(ies) available for 2-hexynyladenosine-5'-n-ethylcarboxamide and adenosine
| Article | Year |
|---|---|
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.
Topics: Adenosine; Animals; Cell Membrane; CHO Cells; Corpus Striatum; Cricetinae; In Vitro Techniques; Magnetic Resonance Spectroscopy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Rats; Recombinant Proteins; Ribose; Structure-Activity Relationship | 1995 |
Modeling hemodynamic profiles by telemetry in the rat. A study with A1 and A2a adenosine agonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-Agonists; Animals; Hemodynamics; Male; Models, Biological; Platelet Aggregation Inhibitors; Rats; Rats, Inbred SHR; Telemetry | 1995 |
Pharmacology of the new selective A2a adenosine receptor agonist 2-hexynyl-5'-N-ethylcarboxamidoadenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Cattle; Dose-Response Relationship, Drug; Electroencephalography; Heart; Hemodynamics; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth, Vascular; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rabbits; Rats; Rats, Sprague-Dawley; Swine | 1994 |
In vivo and ex vivo effects of adenosine A1 and A2 receptor agonists on platelet aggregation in the rabbit.
Topics: Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rabbits | 1994 |
Repeated administration of selective adenosine A1 and A2 receptor agonists in the spontaneously hypertensive rat: tolerance develops to A1-mediated hemodynamic effects.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Drug Tolerance; Hemodynamics; Male; Phenethylamines; Rats; Rats, Inbred SHR; Receptors, Purinergic P1 | 1994 |
Effects of adenosine-receptor agonists on renin release in anaesthetized rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Hemodynamics; Infusions, Intravenous; Kidney; Nerve Fibers; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Renin | 1995 |
Prolonged exposure to 5'-N-ethylcarboxamidoadenosine (NECA) does not affect the adenosine A2A-mediated vasodilation in porcine coronary arteries.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Dinoprost; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Time Factors; Vasodilation; Vasodilator Agents | 1997 |
Adenosine A2A receptor agonists increase Fos-like immunoreactivity in mesolimbic areas.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dopamine Agonists; Immunohistochemistry; Limbic System; Male; Oxidopamine; Phenethylamines; Proto-Oncogene Proteins c-fos; Purinergic Antagonists; Purinergic P1 Receptor Agonists; Pyrimidines; Quinpirole; Rats; Rats, Sprague-Dawley; Triazoles | 1997 |
Mechanism and pressor relevance of the short-term cardiovascular and renin excitatory actions of the selective A2A-adenosine receptor agonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Injections, Intraperitoneal; Male; Phenethylamines; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System | 1997 |
ZM241385 is an antagonist of the facilitatory responses produced by the A2A adenosine receptor agonists CGS21680 and HENECA in the rat hippocampus.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Binding Sites; Hippocampus; Ligands; Membranes; Phenethylamines; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rats; Synaptic Transmission; Synaptosomes; Triazines; Triazoles; Visual Cortex | 1997 |
Effects of adenosine receptor agonists on renal function in anaesthetized rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Denervation; Glomerular Filtration Rate; Hypertension, Renal; Kidney; Male; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Purinergic P1; Receptors, Purinergic P2; Sodium; Urodynamics | 1997 |
Effects of adenosine receptor agonists on efferent renal nerve activity in anesthetized rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Baroreflex; Blood Pressure; Denervation; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Kidney; Male; Neurons, Efferent; Nitroprusside; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Regression Analysis; Sympathetic Nervous System; Time Factors; Vagotomy | 2000 |
Humoral effects of selective adenosine agonists in spontaneously hypertensive rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Heart Rate; Male; Models, Cardiovascular; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred SHR; Renin | 1996 |