2-hexynyladenosine-5'-n-ethylcarboxamide and 2-chloroadenosine

2-hexynyladenosine-5'-n-ethylcarboxamide has been researched along with 2-chloroadenosine in 2 studies

Compound Research Comparison

Studies (2-hexynyladenosine-5'-n-ethylcarboxamide)	Trials (2-hexynyladenosine-5'-n-ethylcarboxamide)	Recent Studies (post-2010) (2-hexynyladenosine-5'-n-ethylcarboxamide)	Studies (2-chloroadenosine)	Trials (2-chloroadenosine)	Recent Studies (post-2010) (2-chloroadenosine)
28	0	2	889	13	47

Protein Interaction Comparison

Protein	Taxonomy	2-chloroadenosine (IC50)
high affinity choline transporter 1 isoform a	Homo sapiens (human)	0.5377
Adenosine receptor A1	Rattus norvegicus (Norway rat)	0.037
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	0.16
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	0.16

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cristalli, G; Esker, JL; Jacobson, KA; Ji, XD; Melman, N; Olah, ME; Schneller, SW; Secrist, JA; Siddiqi, SM; Tiwari, KN	1
Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U	1

Other Studies

2 other study(ies) available for 2-hexynyladenosine-5'-n-ethylcarboxamide and 2-chloroadenosine

Article	Year
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors. Journal of medicinal chemistry, 1995, Mar-31, Volume: 38, Issue:7 Topics: Adenosine; Animals; Cell Membrane; CHO Cells; Corpus Striatum; Cricetinae; In Vitro Techniques; Magnetic Resonance Spectroscopy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Rats; Recombinant Proteins; Ribose; Structure-Activity Relationship	1995
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium	1999

Article

Year

Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.

Journal of medicinal chemistry, 1995, Mar-31, Volume: 38, Issue:7

Topics: Adenosine; Animals; Cell Membrane; CHO Cells; Corpus Striatum; Cricetinae; In Vitro Techniques; Magnetic Resonance Spectroscopy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Rats; Recombinant Proteins; Ribose; Structure-Activity Relationship

1995

Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.

Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1

Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium

1999