2-hexynyladenosine-5'-n-ethylcarboxamide has been researched along with 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine in 9 studies
| Studies (2-hexynyladenosine-5'-n-ethylcarboxamide) | Trials (2-hexynyladenosine-5'-n-ethylcarboxamide) | Recent Studies (post-2010) (2-hexynyladenosine-5'-n-ethylcarboxamide) | Studies (2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine) | Trials (2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine) | Recent Studies (post-2010) (2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine) |
|---|---|---|---|---|---|
| 28 | 0 | 2 | 952 | 2 | 169 |
| Protein | Taxonomy | 2-hexynyladenosine-5'-n-ethylcarboxamide (IC50) | 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine (IC50) |
|---|---|---|---|
| Adenosine receptor A2a | Homo sapiens (human) | 0.019 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abiru, T; Homma, H; Matsuda, A; Murayama, T; Nomura, Y; Watanabe, Y | 1 |
| Borea, PA; Camaioni, E; Conti, A; Cristalli, G; Dionisotti, S; Monopoli, A; Ongini, E; Vittori, S; Volpini, R | 1 |
| Arslan, G; Dionisotti, S; Fredholm, BB; Kull, B; Ongini, E; Zocchi, C | 1 |
| Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U | 1 |
| Bonizzoni, E; Casati, C; Dionisotti, S; Monopoli, A; Ongini, E; Zocchi, C | 1 |
| Conti, A; Lozza, G; Monopoli, A | 1 |
| Cristalli, G; Morelli, M; Pinna, A; Wardas, J | 1 |
| Alberti, C; Casati, C; Forlani, A; Monopoli, A; Morganti, A; Nador, B; Ongini, E; Sala, C | 1 |
| Constantino, MD; Cunha, RA; Ribeiro, JA | 1 |
9 other study(ies) available for 2-hexynyladenosine-5'-n-ethylcarboxamide and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine
| Article | Year |
|---|---|
Nucleosides and nucleotides. 112. 2-(1-Hexyn-1-yl)adenosine-5'-uronamides: a new entry of selective A2 adenosine receptor agonists with potent antihypertensive activity.
Topics: Adenosine; Animals; Antihypertensive Agents; Brain; Male; Molecular Structure; Rats; Rats, Inbred SHR; Receptors, Purinergic; Substrate Specificity | 1992 |
2-Aralkynyl and 2-heteroalkynyl derivatives of adenosine-5'-N-ethyluronamide as selective A2a adenosine receptor agonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Male; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1 | 1995 |
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Species Specificity; Transfection; Triazoles | 1997 |
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium | 1999 |
Repeated administration of selective adenosine A1 and A2 receptor agonists in the spontaneously hypertensive rat: tolerance develops to A1-mediated hemodynamic effects.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Drug Tolerance; Hemodynamics; Male; Phenethylamines; Rats; Rats, Inbred SHR; Receptors, Purinergic P1 | 1994 |
Prolonged exposure to 5'-N-ethylcarboxamidoadenosine (NECA) does not affect the adenosine A2A-mediated vasodilation in porcine coronary arteries.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Dinoprost; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Time Factors; Vasodilation; Vasodilator Agents | 1997 |
Adenosine A2A receptor agonists increase Fos-like immunoreactivity in mesolimbic areas.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dopamine Agonists; Immunohistochemistry; Limbic System; Male; Oxidopamine; Phenethylamines; Proto-Oncogene Proteins c-fos; Purinergic Antagonists; Purinergic P1 Receptor Agonists; Pyrimidines; Quinpirole; Rats; Rats, Sprague-Dawley; Triazoles | 1997 |
Mechanism and pressor relevance of the short-term cardiovascular and renin excitatory actions of the selective A2A-adenosine receptor agonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Injections, Intraperitoneal; Male; Phenethylamines; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System | 1997 |
ZM241385 is an antagonist of the facilitatory responses produced by the A2A adenosine receptor agonists CGS21680 and HENECA in the rat hippocampus.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Binding Sites; Hippocampus; Ligands; Membranes; Phenethylamines; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rats; Synaptic Transmission; Synaptosomes; Triazines; Triazoles; Visual Cortex | 1997 |