Page last updated: 2024-08-20

2-fluoroadenosine and adenosine

2-fluoroadenosine has been researched along with adenosine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's3 (23.08)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Montgomery, JA; Secrist, JA; Shortnacy, AT1
Carlson, EE; Goswami, M; Wilke, KE1
Agarwal, KC; Parks, RE1
Alderfer, JL; Loomis, RE; Zielinski, TJ1
Alves, C; Decking, UK; Schrader, J; Spahr, R1
Chen, ZH; Olopade, OI; Savarese, TM1
Chittur, SV; Davisson, VJ; Deras, ML1
BROCKMAN, RW; CHAMBERS, P; MONCRIEF, C; PITTILLO, RF1
Ealick, SE; Wang, CC; Wang, WH; Wu, SW; Zang, Y1
Alauddin, MM; Conti, PS; Fissekis, JD; Park, R; Shahinian, A; Tohme, M1
de Giuseppe, PO; dos Santos, CR; Martins, NH; Meza, AN; Murakami, MT; Pereira, HD1
Bachega, JF; Brandão-Neto, J; Cassago, A; DeMarco, R; Garratt, RC; Pereira, HD; Romanello, L1
Antonov, KV; Arnautova, AO; Berzina, MY; Dorofeeva, EV; Esipov, RS; Fateev, IV; Kayushin, AL; Konstantinova, ID; Lutonina, OI; Mikhailopulo, IA; Miroshnikov, AI; Paramonov, AS; Tokunova, JA1

Other Studies

13 other study(ies) available for 2-fluoroadenosine and adenosine

ArticleYear
Synthesis and biological evaluation of 2-fluoro-8-azaadenosine and related compounds.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:10

    Topics: Adenosine; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Drug Evaluation, Preclinical; Humans; Indicators and Reagents; Laryngeal Neoplasms; Leukemia P388; Leukemia, Experimental; Magnetic Resonance Spectroscopy; Mice; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

1983
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
    Journal of medicinal chemistry, 2017, 10-12, Volume: 60, Issue:19

    Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship

2017
Synergistic inhibition of platelet aggregation by forskolin plus PGE1 or 2-fluoroadenosine: effects of 2',5'-dideoxyadenosine and 5'-methylthioadenosine.
    Biochemical pharmacology, 1982, Nov-15, Volume: 31, Issue:22

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Alprostadil; Colforsin; Deoxyadenosines; Dideoxyadenosine; Diterpenes; Drug Synergism; Humans; In Vitro Techniques; Platelet Aggregation; Prostaglandins E; Thionucleosides

1982
Fluorinated nucleic acid constituents: a carbon-13 nuclear magnetic resonance study of adenosine, cytidine, uridine, and their fluorinated analogues.
    Biochemistry, 1982, May-25, Volume: 21, Issue:11

    Topics: Adenosine; Chemical Phenomena; Chemistry; Cytidine; Magnetic Resonance Spectroscopy; Uridine

1982
2-Fluoroadenosine uptake by erythrocytes and endothelial cells studied by 19F-NMR.
    The American journal of physiology, 1994, Volume: 266, Issue:4 Pt 2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Endothelium, Vascular; Erythrocytes; Fluorine; Humans; Magnetic Resonance Spectroscopy; Swine

1994
Expression of methylthioadenosine phosphorylase cDNA in p16-, MTAP- malignant cells: restoration of methylthioadenosine phosphorylase-dependent salvage pathways and alterations of sensitivity to inhibitors of purine de novo synthesis.
    Molecular pharmacology, 1997, Volume: 52, Issue:5

    Topics: Adenosine; Antimalarials; Antimetabolites, Antineoplastic; Azaserine; Biomarkers, Tumor; Cell Count; Deoxyadenosines; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Methionine; Methotrexate; Pancreatic Neoplasms; Purine-Nucleoside Phosphorylase; Purines; RNA, Messenger; Thionucleosides; Tumor Cells, Cultured

1997
N2-hydroxyguanosine 5'-monophosphate is a time-dependent inhibitor of Escherichia coli guanosine monophosphate synthetase.
    Biochemistry, 1999, Jan-05, Volume: 38, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Carbon-Nitrogen Ligases; Carbon-Nitrogen Ligases with Glutamine as Amide-N-Donor; Enzyme Activation; Enzyme Inhibitors; Glutaminase; Guanosine Monophosphate; Hydrolysis; Kinetics; Models, Chemical

1999
ANTIMICROBIAL ACTIVITY OF 2-FLUOROADENOSINE AND 2-FLUOROADENINE.
    Antimicrobial agents and chemotherapy, 1964, Volume: 10

    Topics: Adenine; Adenosine; Anti-Infective Agents; Bacteria; Nucleosides; Pharmacology; Research

1964
Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex.
    The Journal of biological chemistry, 2005, Jun-10, Volume: 280, Issue:23

    Topics: Adenine; Adenosine; Animals; Binding Sites; Catalysis; Crystallography, X-Ray; Dose-Response Relationship, Drug; Electrons; Formycins; Humans; Hydrolysis; Inhibitory Concentration 50; Inosine; Ligands; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Purine-Nucleoside Phosphorylase; Recombinant Proteins; Substrate Specificity; Threonine; Time Factors; Trichomonas vaginalis; X-Rays

2005
Biodistribution and PET imaging of [(18)F]-fluoroadenosine derivatives.
    Nuclear medicine and biology, 2007, Volume: 34, Issue:3

    Topics: Adenocarcinoma; Adenosine; Animals; HT29 Cells; Humans; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution

2007
Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Acyclovir; Adenosine; Bacillus subtilis; Catalysis; Catalytic Domain; Crystallography, X-Ray; Ganciclovir; Genetic Therapy; Humans; Ligands; Models, Molecular; Molecular Conformation; Neoplasms; Phosphates; Prodrugs; Protein Structure, Quaternary; Purine-Nucleoside Phosphorylase; Serine; Threonine; Tubercidin

2012
Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues.
    Acta crystallographica. Section D, Biological crystallography, 2013, Volume: 69, Issue:Pt 1

    Topics: Adenosine; Adenosine Kinase; Animals; Crystallization; Crystallography, X-Ray; Humans; Schistosoma mansoni; Sequence Alignment; Substrate Specificity

2013
Radical Dehalogenation and Purine Nucleoside Phosphorylase
    Biomolecules, 2021, 04-07, Volume: 11, Issue:4

    Topics: Adenosine; Biocatalysis; Deoxyadenosines; Deuterium Oxide; Escherichia coli; Escherichia coli Proteins; Hydrolysis; Inosine; Purine-Nucleoside Phosphorylase; Substrate Specificity

2021