Compounds > 2'fluoro-2'-deoxyuridine
Page last updated: 2024-09-04

2'fluoro-2'-deoxyuridine and floxuridine

2'fluoro-2'-deoxyuridine has been researched along with floxuridine in 8 studies

Compound Research Comparison

Studies
(2'fluoro-2'-deoxyuridine)		Trials
(2'fluoro-2'-deoxyuridine)		Recent Studies (post-2010)
(2'fluoro-2'-deoxyuridine)		Studies
(floxuridine)		Trials
(floxuridine)		Recent Studies (post-2010) (floxuridine)
13043,556323280

Protein Interaction Comparison

ProteinTaxonomy2'fluoro-2'-deoxyuridine (IC50)floxuridine (IC50)
Thymidylate synthaseMus musculus (house mouse)1.0862

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's3 (37.50)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cech, D; Krynetskaya, NF; Metelev, VG; Niemann, A; Oretskaya, TS; Schmidt, S; Shabarova, ZA; Suchomlinov, VV1
Abrams, DN; Knaus, EE; Lee, YW; Mercer, JR; Wiebe, LI1
Gati, WP; Knaus, EE; Wiebe, LI1
Iwai, S; Kataoka, S; Nakamura, H; Ohtsuka, E; Wakasa, M1
Collins, JM; Katki, AG; Klecker, RW1
Bruner, SD; Sekino, Y; Verdine, GL1
Cao, C; Jiang, YL; McDowell, LM; Poliks, B; Potter, GS; Schaefer, J; Song, F; Stivers, JT; Studelska, DR1
Lee, J; Lee, Y; Sullenger, BA; Urban, JH; Xu, L1

Other Studies

8 other study(ies) available for 2'fluoro-2'-deoxyuridine and floxuridine

ArticleYear
The use of oligonucleotide probes containing 2'-deoxy-2'-fluoronucleosides for regiospecific cleavage of RNA by RNase H from Escherichia coli.
    Biochimica et biophysica acta, 1992, Feb-28, Volume: 1130, Issue:1

    Topics: Base Sequence; Deoxycytidine; Escherichia coli; Floxuridine; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotide Probes; Ribonuclease H; RNA, Bacterial; RNA, Ribosomal, 5S; RNA, Transfer, Phe

1992
Tumour uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models. IX. Radiolabelled 1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)uracil and 1-(2'-chloro-2'-deoxy-beta-D-ribofuranosyl)uracil.
    The British journal of radiology, 1986, Volume: 59, Issue:699

    Topics: Animals; Carbon Radioisotopes; Carcinoma 256, Walker; Chlorine; Deoxyuridine; Floxuridine; Lung Neoplasms; Mice; Radioisotopes; Rats; Rats, Inbred Strains; Tissue Distribution; Uracil; Uridine

1986
Interaction of 2'-halogeno-2'-deoxyuridines with the human erythrocyte nucleoside transport mechanism.
    Molecular pharmacology, 1983, Volume: 23, Issue:1

    Topics: Binding, Competitive; Biological Transport, Active; Bromodeoxyuridine; Deoxyuridine; Erythrocyte Membrane; Erythrocytes; Floxuridine; Humans; Idoxuridine; Kinetics; Nucleosides; Structure-Activity Relationship; Thymidine

1983
Recognition of 2'-hydroxyl groups by Escherichia coli ribonuclease HI.
    FEBS letters, 1995, Jul-17, Volume: 368, Issue:2

    Topics: Base Sequence; Deoxyuridine; Escherichia coli; Floxuridine; Hydrogen Bonding; Hydroxyl Radical; Kinetics; Models, Molecular; Molecular Sequence Data; Oligonucleotides; Protein Structure, Tertiary; Ribonuclease H; Ribonucleosides

1995
Suicide prodrugs activated by thymidylate synthase: rationale for treatment and noninvasive imaging of tumors with deoxyuridine analogues.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:8

    Topics: Animals; Arabinofuranosyluracil; Cell Division; DNA; Floxuridine; Fluorine Radioisotopes; Humans; Methylation; Mice; Neoplasms; Phosphorylation; Prodrugs; Thymidylate Synthase; Tumor Cells, Cultured

1999
Selective inhibition of herpes simplex virus type-1 uracil-DNA glycosylase by designed substrate analogs.
    The Journal of biological chemistry, 2000, Nov-24, Volume: 275, Issue:47

    Topics: Base Sequence; DNA Glycosylases; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Floxuridine; Furans; Herpesvirus 1, Human; Humans; Isomerism; Models, Chemical; Molecular Mimicry; Molecular Sequence Data; N-Glycosyl Hydrolases; Uracil-DNA Glycosidase

2000
Recognition of an unnatural difluorophenyl nucleotide by uracil DNA glycosylase.
    Biochemistry, 2004, Dec-14, Volume: 43, Issue:49

    Topics: Amino Acid Substitution; Binding Sites; Catalysis; DNA Glycosylases; Enzyme Stability; Escherichia coli Proteins; Floxuridine; Fluorine; Hydrogen Bonding; Leucine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Heteroduplexes; Solutions; Spectrometry, Fluorescence; Substrate Specificity; Thermodynamics; Uracil; Uracil-DNA Glycosidase

2004
2'Fluoro Modification Differentially Modulates the Ability of RNAs to Activate Pattern Recognition Receptors.
    Nucleic acid therapeutics, 2016, Volume: 26, Issue:3

    Topics: Cell Death; Cytokines; Floxuridine; Gene Expression Regulation; Humans; Nucleic Acid Conformation; Receptors, Pattern Recognition; RNA; Toll-Like Receptor 3

2016