2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and nelfinavir

2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine has been researched along with nelfinavir in 1 studies

Compound Research Comparison

Studies (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)	Trials (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)	Recent Studies (post-2010) (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)	Studies (nelfinavir)	Trials (nelfinavir)	Recent Studies (post-2010) (nelfinavir)
135	6	50	1,240	230	240

Protein Interaction Comparison

Protein	Taxonomy	nelfinavir (IC50)
Tyrosine-protein kinase Fyn	Homo sapiens (human)	7.971
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	8.852
ATP-dependent translocase ABCB1	Homo sapiens (human)	3.3938
Cytochrome P450 3A4	Homo sapiens (human)	1.275
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	2.3
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	8.852
Protease	Human immunodeficiency virus 1	0.53
Protease	Human immunodeficiency virus 1	0.0054

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fang, WB; Lin, SN; Moody, DE; Omiecinski, CJ; Strom, SC; Weyant, DM	1

Other Studies

1 other study(ies) available for 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and nelfinavir

Article	Year
Effect of rifampin and nelfinavir on the metabolism of methadone and buprenorphine in primary cultures of human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:12 Topics: Adult; Aged; Analgesics, Opioid; Antibiotics, Antitubercular; Biotransformation; Buprenorphine; Cells, Cultured; Chromatography, Liquid; Dealkylation; Drug Interactions; Female; Glucuronides; Hepatocytes; HIV Protease Inhibitors; Humans; Intestinal Mucosa; Kinetics; Male; Methadone; Microsomes, Liver; Middle Aged; Nelfinavir; Pyrrolidines; Rifampin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry	2009

Article

Year

Effect of rifampin and nelfinavir on the metabolism of methadone and buprenorphine in primary cultures of human hepatocytes.

Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:12

Topics: Adult; Aged; Analgesics, Opioid; Antibiotics, Antitubercular; Biotransformation; Buprenorphine; Cells, Cultured; Chromatography, Liquid; Dealkylation; Drug Interactions; Female; Glucuronides; Hepatocytes; HIV Protease Inhibitors; Humans; Intestinal Mucosa; Kinetics; Male; Methadone; Microsomes, Liver; Middle Aged; Nelfinavir; Pyrrolidines; Rifampin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2009