2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine has been researched along with naloxone in 2 studies
| Studies (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) | Trials (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) | Recent Studies (post-2010) (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 135 | 6 | 50 | 20,134 | 1,257 | 3,321 |
| Protein | Taxonomy | 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, BS; Chen, CT; Hsu, TI; Huang, MH; Kang, YF; Shen, AY; Wang, TS; Wu, HM; Wu, SN | 1 |
| Blendy, JA; Forcelli, PA; Kellar, KJ; Lee, BG; Olson, TT; Turner, JR; Xiao, Y; Xie, T | 1 |
2 other study(ies) available for 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and naloxone
| Article | Year |
|---|---|
Inhibitory action of methadone and its metabolites on erg-mediated K+ current in GH₃ pituitary tumor cells.
Topics: Animals; Cell Line, Tumor; Ether-A-Go-Go Potassium Channels; Methadone; Naloxone; Narcotics; Neurons; Pituitary Neoplasms; Prolactin; Pyrrolidines; Rats; Risperidone | 2011 |
Anxiolytic- and antidepressant-like effects of the methadone metabolite 2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline (EMDP).
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Blepharoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Naloxone; Protein Binding; Pyrrolidines; Rats; Rats, Sprague-Dawley; Swimming; Time Factors; Tritium | 2016 |