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2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and morphine

2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine has been researched along with morphine in 10 studies

Compound Research Comparison

Studies
(2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)
Trials
(2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)
Recent Studies (post-2010)
(2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
13565044,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomy2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's4 (40.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Nagashima, R; Nishikawa, T; Tobita, M1
Bermejo, AM; Fernández, P; Morales, L; Tabernero, MJ; Vázquez, C1
Bones, J; Paull, B; Thomas, KV1
Bermejo, AM; Carro, AM; Fernández, P; Lago, M; Lorenzo, RA; Tabernero, MJ1
Chen, ACh; Chen, CH; Chen, YT; Fang, CP; Ho, IK; Hsiao, CF; Hsu, YT; Huang, CL; Kuo, HW; Lin, L; Liu, CT; Liu, ML; Liu, SC; Liu, YL; Shih, YH; Su, LW; Tan, HK; Tian, JN; Tsou, HH; Wu, CS; Yang, YH; Yang, YT1
Barbera, N; Busardò, FP; Indorato, F; Romano, G1
Favretto, D; Ferrara, SD; Miolo, G; Monaldi, A; Tucci, M1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M1
Evrard, CA; Haas, DM; Haneline, LS; Jones, DR; Masters, AR; Metzger, IF; Quinney, SK; Thomas, AE1
Buratti, E; Cerioni, A; Cingolani, M; Cippitelli, M; Froldi, R; Mietti, G; Scendoni, R1

Other Studies

10 other study(ies) available for 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and morphine

ArticleYear
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
HPLC-DAD determination of opioids, cocaine and their metabolites in plasma.
    Forensic science international, 2006, Aug-10, Volume: 161, Issue:1

    Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Codeine; Dopamine Uptake Inhibitors; Female; Forensic Medicine; Humans; Male; Methadone; Morphine; Morphine Derivatives; Pyrrolidines

2006
Using environmental analytical data to estimate levels of community consumption of illicit drugs and abused pharmaceuticals.
    Journal of environmental monitoring : JEM, 2007, Volume: 9, Issue:7

    Topics: Chromatography, Liquid; Cities; Cocaine; Environmental Monitoring; Humans; Illicit Drugs; Ireland; Morphine; Pharmaceutical Preparations; Pyrrolidines; Residence Characteristics; Rivers; Solid Phase Extraction; Substance-Related Disorders; Tandem Mass Spectrometry; Temazepam; Waste Disposal, Fluid; Water Pollutants, Chemical

2007
Microwave-assisted extraction and HPLC-DAD determination of drugs of abuse in human plasma.
    Journal of analytical toxicology, 2007, Volume: 31, Issue:7

    Topics: Calibration; Chromatography, High Pressure Liquid; Cocaine; Codeine; Forensic Medicine; Humans; Illicit Drugs; Methadone; Microwaves; Morphine; Pyrrolidines; Reproducibility of Results; Solvents; Spectrophotometry, Atomic; Substance Abuse Detection

2007
UGT2B7 genetic polymorphisms are associated with the withdrawal symptoms in methadone maintenance patients.
    Pharmacogenomics, 2012, Volume: 13, Issue:8

    Topics: Adult; Amitriptyline; Female; Genetic Association Studies; Glucuronosyltransferase; Haplotypes; Heroin Dependence; Humans; Linkage Disequilibrium; Male; Methadone; Middle Aged; Morphine; Polymorphism, Single Nucleotide; Pyrrolidines; Substance Withdrawal Syndrome; Taiwan

2012
The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome.
    Forensic science international, 2013, Apr-10, Volume: 227, Issue:1-3

    Topics: Adult; Anesthetics, Local; Antitussive Agents; Bile; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Citalopram; Codeine; Dextromethorphan; Drug Contamination; Drug Overdose; Drug Users; Female; Forensic Pathology; Forensic Toxicology; Gastrointestinal Contents; Humans; Illicit Drugs; Kidney; Lidocaine; Liver; Lung; Male; Methadone; Morphine; Morphine Derivatives; Narcotics; Pyrrolidines; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders; Vitreous Body

2013
A study on photodegradation of methadone, EDDP, and other drugs of abuse in hair exposed to controlled UVB radiation.
    Drug testing and analysis, 2014, Volume: 6 Suppl 1

    Topics: Analgesics, Opioid; Cocaine; Hair; Humans; Methadone; Morphine; Morphine Derivatives; Photolysis; Pyrrolidines; Substance Abuse Detection; Ultraviolet Rays

2014
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2014
Stereoselective Analysis of Methadone and EDDP in Laboring Women and Neonates in Plasma and Dried Blood Spots and Association with Neonatal Abstinence Syndrome.
    American journal of perinatology, 2021, Volume: 38, Issue:9

    Topics: Analgesics, Opioid; Anticonvulsants; Dried Blood Spot Testing; Female; Humans; Infant, Newborn; Labor, Obstetric; Methadone; Morphine; Neonatal Abstinence Syndrome; Phenobarbital; Pregnancy; Pyrrolidines

2021
Detection of Three Opioids (Morphine, Codeine and Methadone) and Their Metabolites (6-Monoacetylmorphine and 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) in Larvae of
    Molecules (Basel, Switzerland), 2023, Jun-08, Volume: 28, Issue:12

    Topics: Analgesics, Opioid; Animals; Chromatography, High Pressure Liquid; Codeine; Diptera; Humans; Larva; Methadone; Morphine; Morphine Derivatives

2023