2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine has been researched along with mephenytoin in 1 studies
| Studies (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) | Trials (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) | Recent Studies (post-2010) (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) | Studies (mephenytoin) | Trials (mephenytoin) | Recent Studies (post-2010) (mephenytoin) |
|---|---|---|---|---|---|
| 135 | 6 | 50 | 580 | 35 | 32 |
| Protein | Taxonomy | 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (IC50) | mephenytoin (IC50) |
|---|---|---|---|
| Cytochrome P450 2C19 | Homo sapiens (human) | 1.185 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prost, F; Thormann, W | 1 |
1 other study(ies) available for 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and mephenytoin
| Article | Year |
|---|---|
Capillary electrophoresis to assess drug metabolism induced in vitro using single CYP450 enzymes (Supersomes): application to the chiral metabolism of mephenytoin and methadone.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Electrophoresis, Capillary; Humans; Mephenytoin; Methadone; Microsomes, Liver; Pharmaceutical Preparations; Pyrrolidines; Stereoisomerism | 2003 |