Page last updated: 2024-09-03

2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and diphenhydramine

2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine has been researched along with diphenhydramine in 2 studies

Compound Research Comparison

Studies
(2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)
Trials
(2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)
Recent Studies (post-2010)
(2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)
Studies
(diphenhydramine)
Trials
(diphenhydramine)
Recent Studies (post-2010) (diphenhydramine)
1356504,146415542

Protein Interaction Comparison

ProteinTaxonomy2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (IC50)diphenhydramine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.98
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.542
Muscarinic acetylcholine receptor M2Homo sapiens (human)1.05
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.372
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.162
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.346
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.647
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.542
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.295
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.98
Histamine H1 receptorHomo sapiens (human)0.171
5-hydroxytryptamine receptor 2BHomo sapiens (human)1.118
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)3.8852

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagashima, R; Nishikawa, T; Tobita, M1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M1

Other Studies

2 other study(ies) available for 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and diphenhydramine

ArticleYear
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2014