Page last updated: 2024-09-03

2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and codeine

2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine has been researched along with codeine in 10 studies

Compound Research Comparison

Studies
(2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)
Trials
(2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)
Recent Studies (post-2010)
(2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine)
Studies
(codeine)
Trials
(codeine)
Recent Studies (post-2010) (codeine)
1356504,815730952

Protein Interaction Comparison

ProteinTaxonomy2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (IC50)codeine (IC50)
Delta-type opioid receptorMus musculus (house mouse)10
Kappa-type opioid receptorMus musculus (house mouse)10
Mu-type opioid receptorHomo sapiens (human)0.105
Mu-type opioid receptorMus musculus (house mouse)10

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (30.00)29.6817
2010's6 (60.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Nagashima, R; Nishikawa, T; Tobita, M1
Bermejo, AM; Fernández, P; Morales, L; Tabernero, MJ; Vázquez, C1
Bermejo, AM; Carro, AM; Fernández, P; Lago, M; Lorenzo, RA; Tabernero, MJ1
Aguilar, C; Borrull, F; Botello, I; Calull, M1
Carro, AM; Fernández, P; Lorenzo, RA; Seoane, S; Tabernero, MJ; Vázquez, C1
Aguilar, C; Borrull, F; Botello, I; Calull, M; de Jong, GJ; Somsen, GW1
Barbera, N; Busardò, FP; Indorato, F; Romano, G1
Ihenetu, K; Na, S; Rosano, TG; Swift, TA; Wood, M1
Bruno, R; Hall, W; Lai, FY; Mueller, JF; O'Brien, J; Prichard, J; Thai, PK; van Dyken, E1
Buratti, E; Cerioni, A; Cingolani, M; Cippitelli, M; Froldi, R; Mietti, G; Scendoni, R1

Other Studies

10 other study(ies) available for 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine and codeine

ArticleYear
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
HPLC-DAD determination of opioids, cocaine and their metabolites in plasma.
    Forensic science international, 2006, Aug-10, Volume: 161, Issue:1

    Topics: Analgesics, Opioid; Chromatography, High Pressure Liquid; Cocaine; Codeine; Dopamine Uptake Inhibitors; Female; Forensic Medicine; Humans; Male; Methadone; Morphine; Morphine Derivatives; Pyrrolidines

2006
Microwave-assisted extraction and HPLC-DAD determination of drugs of abuse in human plasma.
    Journal of analytical toxicology, 2007, Volume: 31, Issue:7

    Topics: Calibration; Chromatography, High Pressure Liquid; Cocaine; Codeine; Forensic Medicine; Humans; Illicit Drugs; Methadone; Microwaves; Morphine; Pyrrolidines; Reproducibility of Results; Solvents; Spectrophotometry, Atomic; Substance Abuse Detection

2007
Investigation of in-line solid-phase extraction capillary electrophoresis for the analysis of drugs of abuse and their metabolites in water samples.
    Electrophoresis, 2012, Volume: 33, Issue:3

    Topics: Cocaine; Codeine; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Illicit Drugs; Limit of Detection; Morphine Derivatives; Pyrrolidines; Regression Analysis; Reproducibility of Results; Rivers; Solid Phase Extraction; Water Pollutants, Chemical; Water Supply

2012
Chromatographic determination of drugs of abuse in vitreous humor using solid-phase extraction.
    Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:8

    Topics: Chromatography, High Pressure Liquid; Cocaine; Codeine; Humans; Illicit Drugs; Morphine Derivatives; Pyrrolidines; Reproducibility of Results; Solid Phase Extraction; Vitreous Body

2013
In-line solid-phase extraction-capillary electrophoresis coupled with mass spectrometry for determination of drugs of abuse in human urine.
    Analytical and bioanalytical chemistry, 2012, Volume: 403, Issue:3

    Topics: Codeine; Electrophoresis, Capillary; Humans; Illicit Drugs; Limit of Detection; Morphine Derivatives; Pyrrolidines; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization

2012
The pathogenetic role of adulterants in 5 cases of drug addicts with a fatal outcome.
    Forensic science international, 2013, Apr-10, Volume: 227, Issue:1-3

    Topics: Adult; Anesthetics, Local; Antitussive Agents; Bile; Brain Chemistry; Caffeine; Central Nervous System Stimulants; Citalopram; Codeine; Dextromethorphan; Drug Contamination; Drug Overdose; Drug Users; Female; Forensic Pathology; Forensic Toxicology; Gastrointestinal Contents; Humans; Illicit Drugs; Kidney; Lidocaine; Liver; Lung; Male; Methadone; Morphine; Morphine Derivatives; Narcotics; Pyrrolidines; Selective Serotonin Reuptake Inhibitors; Substance-Related Disorders; Vitreous Body

2013
Multi-drug and metabolite quantification in postmortem blood by liquid chromatography-high-resolution mass spectrometry: comparison with nominal mass technology.
    Journal of analytical toxicology, 2014, Volume: 38, Issue:8

    Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Citalopram; Cocaine; Codeine; Dextromethorphan; Diphenhydramine; Evaluation Studies as Topic; Forensic Pathology; Humans; Hydrocodone; Hydromorphone; Meperidine; Methadone; Morphine; Oxycodone; Oxymorphone; Pyrrolidines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2014
Refining the excretion factors of methadone and codeine for wastewater analysis - Combining data from pharmacokinetic and wastewater studies.
    Environment international, 2016, Volume: 94

    Topics: Analgesics, Opioid; Codeine; Humans; Methadone; Pyrrolidines; Wastewater; Water Pollutants, Chemical

2016
Detection of Three Opioids (Morphine, Codeine and Methadone) and Their Metabolites (6-Monoacetylmorphine and 2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) in Larvae of
    Molecules (Basel, Switzerland), 2023, Jun-08, Volume: 28, Issue:12

    Topics: Analgesics, Opioid; Animals; Chromatography, High Pressure Liquid; Codeine; Diptera; Humans; Larva; Methadone; Morphine; Morphine Derivatives

2023