Compounds > 2-ethyl-2-methyl-4-butyrolactone
Page last updated: 2024-09-05

2-ethyl-2-methyl-4-butyrolactone and 4-butyrolactone

2-ethyl-2-methyl-4-butyrolactone has been researched along with 4-butyrolactone in 6 studies

Compound Research Comparison

Studies
(2-ethyl-2-methyl-4-butyrolactone)		Trials
(2-ethyl-2-methyl-4-butyrolactone)		Recent Studies (post-2010)
(2-ethyl-2-methyl-4-butyrolactone)		Studies
(4-butyrolactone)		Trials
(4-butyrolactone)		Recent Studies (post-2010) (4-butyrolactone)
9004,456781,823

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Covey, DF; Ferrendelli, JA; Holland, KD; Rothman, SM; Yoon, KW1
Covey, DF; Ferrendelli, JA; Levine, JA1
Ferrendelli, JA; Klunk, WE; McKeon, AC1
Covey, DF; Ferrendelli, JA; Klunk, WE; McKeon, A1
Covey, DF; Rothman, SM; Yoon, KW1
Covey, DF; Ferrendelli, JA; Gross, RA1

Other Studies

6 other study(ies) available for 2-ethyl-2-methyl-4-butyrolactone and 4-butyrolactone

ArticleYear
Gamma-butyrolactone antagonism of the picrotoxin receptor: comparison of a pure antagonist and a mixed antagonist/inverse agonist.
    Molecular pharmacology, 1991, Volume: 39, Issue:1

    Topics: 4-Butyrolactone; Animals; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Rats; Receptors, GABA-A

1991
Convulsant and anti-convulsant gammabutyrolactones bind at the picrotoxinin/T-butylbicyclophosphorothionate (TBPS) receptor.
    Biochemical pharmacology, 1985, Dec-01, Volume: 34, Issue:23

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Convulsants; Furans; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A

1985
Effects of alkyl-substituted gamma-butyrolactones and succinimides on the evoked and spontaneous activity of hippocampal slices in vitro.
    Experimental neurology, 1983, Volume: 82, Issue:3

    Topics: 4-Butyrolactone; Animals; Evoked Potentials; Female; Furans; Guinea Pigs; Hippocampus; In Vitro Techniques; Sodium Oxybate; Succinimides

1983
Alpha-substituted gamma-butyrolactones: new class of anticonvulsant drugs.
    Science (New York, N.Y.), 1982, Sep-10, Volume: 217, Issue:4564

    Topics: 4-Butyrolactone; Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Convulsants; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Ethosuximide; Furans; Guinea Pigs; Mice; Structure-Activity Relationship; Trimethadione

1982
Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons.
    The Journal of physiology, 1993, Volume: 464

    Topics: 4-Butyrolactone; Animals; Chlorides; Electric Conductivity; gamma-Aminobutyric Acid; Hippocampus; Neurons; Picrotoxin; Rats; Reaction Time

1993
Voltage-dependent calcium channels as targets for convulsant and anticonvulsant alkyl-substituted thiobutyrolactones.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: 4-Butyrolactone; Animals; Animals, Newborn; Anticonvulsants; Calcium Channels; Cells, Cultured; Convulsants; Ethosuximide; Evoked Potentials; Ganglia, Spinal; Membrane Potentials; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley

1997