2-chloroethyl ethyl sulfide has been researched along with mustard gas in 127 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (4.72) | 18.7374 |
| 1990's | 12 (9.45) | 18.2507 |
| 2000's | 34 (26.77) | 29.6817 |
| 2010's | 57 (44.88) | 24.3611 |
| 2020's | 18 (14.17) | 2.80 |
| Authors | Studies |
|---|---|
| Caldwell, WM; Griest, WH; Ho, CH; Ramsey, RS | 1 |
| Hoffman, JL; Mozier, NM | 1 |
| Habraken, Y; Ludlum, DB | 1 |
| Rohrbaugh, DK; Ward, JR; Yang, YC | 1 |
| Kent, S; Ludlum, DB; Mehta, JR | 1 |
| Ludlum, DB; Papirmeister, B | 1 |
| Kirk, MC; Ludlum, DB; Mehta, JR; Papirmeister, B; Tong, WP | 1 |
| Gross, CL; Papirmeister, B; Petrali, J; Watson, CV | 1 |
| Gray, PJ | 1 |
| Arroyo, CM; Broomfield, CA; Von Tersch, RL | 1 |
| Cha, SH; Choi, DS; Kim, YB; Park, YK; Sok, DE | 1 |
| Cha, SH; Choi, DS; Kim, YB; Shin, S; Sok, DE | 1 |
| Cha, SH; Choi, DS; Kim, YB; Lee, YS; Sok, DE | 2 |
| Broomfield, CA; Meier, HL; Millard, CB | 1 |
| Choi, DS; Hur, GH; Kim, JH; Kim, YB; Shin, S | 1 |
| Ali, AH; Brozetti, J; Devamanoharan, PS; Henein, M; Lehnert, E; Petrali, J; Varma, SD | 1 |
| Ali, AH; Brozetti, J; Devamanoharan, PS; Lehnert, E; Petrali, J; Varma, SD; Weir, A | 1 |
| Blaha, M; Bowers, W; DuBose, D; Kohl, J; Walker, J | 2 |
| Ludlum, DB; Matijasevic, Z; Precopio, ML; Snyder, JE | 1 |
| Alkhyyat, A; Blaha, M; Bowers, W; DuBose, D; Kohl, J; Walker, J; Wong, G | 1 |
| Clark, CR; Price, EO; Schlager, JJ; Shih, ML; Smith, JR | 1 |
| Arroyo, CM; Carmichael, AJ; Schafer, RJ | 1 |
| Qui, M; Smith, M; Stone, WL | 1 |
| Chatterjee, D; Das, SK; Mukherjee, S; Smith, MG | 2 |
| Klabunde, KJ; Martyanov, IN | 1 |
| Gates, KS; Zang, H | 1 |
| Boulares, AH; Espinoza, LA; Han, S; Liao, H; Smulson, ME | 1 |
| Croxton, MD; Dillman, JF; Dorsch, LM; Hege, AI; Moran, TS; Phillips, CS; Sciuto, AM; Sylvester, AJ | 1 |
| Fang, H; Liu, M; Zeng, Z | 1 |
| Fu, XZ; Han, ST; Wang, XX; Xi, HL | 1 |
| Chatterjee, D; Das, SK; Ghosh, S; Grimes, A; Mukherjee, S; Shen, Y; Smith, M | 1 |
| Das, SK; Kabir, S; Mukherjee, S; Rajaratnam, V; Sinha Roy, S; Smith, M | 1 |
| Biggs, KB; Stuart, DA; Van Duyne, RP | 1 |
| Das, SK; Mukherjee, S; Mukhopadhyay, S; Rajaratnam, V; Smith, M | 1 |
| Paromov, VM; Qui, M; Smith, M; Stone, WL; Yang, H | 1 |
| Matijasevic, Z; Volkert, MR | 1 |
| Castagna, MP; Gordon, RK; Isidore, MA; Nambiar, MP; Steele, KE | 1 |
| Blake, RS; Cordell, RL; Ellis, AM; Monks, PS; Willis, KA; Wyche, KP | 1 |
| Flierl, MA; Hoesel, LM; McClintock, SD; Niederbichler, AD; Pianko, MJ; Reuben, JS; Rittirsch, D; Sarma, JV; Smith, M; Stone, W; Ward, PA; Yang, H | 1 |
| Paromov, V; Qui, M; Smith, M; Stone, WL; Yang, H | 1 |
| Das, SK; Mukherjee, S; Mukhopadhyay, S; Smith, M | 1 |
| Midey, AJ; Miller, TM; Viggiano, AA | 1 |
| Billack, B; Pino, MA | 1 |
| Day, BJ; Gould, NS; White, CW | 1 |
| Agarwal, R; Gu, M; Orlicky, DJ; Pal, A; Rana, S; Tewari-Singh, N; White, CW | 1 |
| Blain, PG; Jowsey, PA; Williams, FM | 1 |
| Saxena, A; Sharma, A; Singh, B; Srivastava, AK | 1 |
| Das, SK; Mukherjee, S; Mukhopadhyay, S; Smith, M; Stone, WL | 1 |
| Agarwal, C; Agarwal, R; Day, BJ; Gu, M; Huang, J; Pal, A; Tewari-Singh, N; White, CW | 1 |
| Anderson, K; Green, AC; Jenner, J; Lindsay, CD; Sayer, NM; Whiting, R | 1 |
| Boulware, S; MacLeod, MC; Powell, KL; Thames, H; Vasquez, KM | 1 |
| Day, BJ; Hendry-Hofer, TB; Huang, J; Loader, JE; Min, E; O'Neill, HC; Rancourt, RC; Veress, LA; White, CW | 1 |
| Casillas, RP; Gray, JP; Heck, DE; Jan, YH; Laskin, DL; Laskin, JD; Zheng, H | 1 |
| Agarwal, C; Agarwal, R; Gu, M; Tewari-Singh, N; White, CW | 1 |
| Gray, JP; Heck, DE; Laskin, DL; Laskin, JD; Mishin, V | 1 |
| Black, AT; Casillas, RP; Gerecke, DR; Hayden, PJ; Heck, DE; Laskin, DL; Laskin, JD; Sinko, PJ | 2 |
| Agarwal, C; Agarwal, R; Day, BJ; Huang, J; Tewari-Singh, N; White, CW | 1 |
| Loke, WK; Ng, ET; Sim, MK | 1 |
| Gow, AJ; Laskin, DL; Laskin, JD; Patel-Vayas, K; Shen, J; Sunil, VR | 2 |
| Agarwal, R; Jain, AK; Orlicky, DJ; Tewari-Singh, N; White, CW | 1 |
| Brannon, M; Kumari, S; Paromov, V; Qui, M; Samala, M; Smith, M; Stone, WL | 1 |
| Fabio, KM; Flowers, RA; Guillon, CD; Harman, MP; Heck, DE; Heindel, ND; Huang, MT; Laskin, JD; Saxena, J; Vetrano, AM; Young, SC | 1 |
| Ganesan, K; Jain, R; Mahato, TH; Prasad, GK; Singh, B; Srivastava, AK; Vijayaraghavan, R | 1 |
| Cooks, RG; Noll, RJ; Smith, JN | 1 |
| Day, BJ; Hendry-Hofer, TB; Loader, JE; O'Neill, HC; Orlicky, DJ; White, CW | 1 |
| Agarwal, R; Gu, M; Inturi, S; Jain, AK; Tewari-Singh, N; White, CW | 1 |
| Abel, EL; Andreeff, M; Bubel, JD; DiGiovanni, J; MacLeod, MC; McClellan, SA; Powell, L; Simper, MS | 1 |
| Das, SK; Gadsden-Gray, J; Mukherjee, S; Ogunkua, O | 1 |
| Agarwal, C; Agarwal, R; Gomez, J; Gu, M; Inturi, S; Shrotriya, S; Tewari-Singh, N; White, CW | 1 |
| Guo, X; Hendry-Hofer, TB; Jones, TN; Rancourt, RC; Veress, LA; White, CW | 1 |
| Abel, EL; Boulware, S; Fields, T; MacLeod, MC; McIvor, E; Powell, KL; Vasquez, KM | 1 |
| Agarwal, C; Agarwal, R; Inturi, S; Jain, AK; Tewari-Singh, N; White, CW | 1 |
| Abel, EL; Boulware, S; DiGiovanni, J; Fields, T; MacLeod, MC; McIvor, E; Powell, KL; Vasquez, KM | 1 |
| Billack, B; Pietka-Ottlik, M; Pino, MA | 1 |
| Ahmad, A; Garlick, RB; Hendry-Hofer, TB; Rancourt, RC; Rioux, JS; Veress, LA; White, CW | 1 |
| Bae, SY; Winemiller, MD | 1 |
| Kehe, K; Schrettl, V; Steinritz, D; Thiermann, H | 1 |
| Ambhore, PD; Deb, U; Pathak, U; Pawar, PP; Satpute, RM; Sawale, SD | 1 |
| Fouse, JC; Lalain, TA; Mantooth, BA; Pearl, TP; Riley, PC; Varady, MJ; Willis, MP | 1 |
| Gupta, T; Singh, V | 1 |
| Garlick, RB; Hendry-Hofer, TB; Houin, PR; Loader, JE; Rancourt, RC; Rioux, JS; Veress, LA; White, CW | 1 |
| Ahmad, A; Garlick, RB; Rancourt, RC; Rioux, JS; Veress, LA; White, CW | 1 |
| Agarwal, C; Agarwal, R; Day, BJ; Inturi, S; Jain, AK; Orlicky, DJ; Tewari-Singh, N; White, CW | 1 |
| Behrens, E; Bennett, RA; Duncheon, C; Lamkin, TJ; Zinn, A | 1 |
| Behera, RR; Kumar, P; Pal, A; Sagar, S | 1 |
| Balszuweit, F; Büch, T; Gudermann, T; Mückter, H; Schäfer, E; Schmidt, A; Steinritz, D; Stenger, B; Thiermann, H; Zehfuss, F | 1 |
| Barsang, MJ; Maddah, B; Rahimi-Nasrabadi, M; Shamsi, J | 1 |
| Balszuweit, F; Birtel, M; Burckhardt-Boer, W; Bürkle, A; Debiak, M; Lex, K; Mangerich, A; Martello, R; Ponath, V; Schmidt, A; Siegert, M; Steinritz, D; Strobelt, R; Thiermann, H | 1 |
| Burckhardt-Boer, W; Bürkle, A; Debiak, M; Lex, K; Mangerich, A; Ponath, V; Schmidt, A; Steinritz, D; Thiermann, H | 1 |
| Asia, L; Doumenq, P; Josse, D; Lacoste, A; Maloni, P; Piram, A; Prevost, P; Spiandore, M; Torre, F | 1 |
| Pal, A; Pal, S; Parida, SR; Rizwan, H; Sabnam, S; Sagar, S; Swain, MM | 1 |
| Béracochéa, D; Dorandeu, F; Gros-Désormeaux, F; Piérard, C | 1 |
| Boekhoff, I; Branoner, F; Gudermann, T; Lüling, R; Popp, T; Seeger, T; Steinritz, D; Thiermann, H; Worek, F | 1 |
| Doumenq, P; Josse, D; Lacoste, A; Piram, A; Souilah-Edib, M; Spiandore, M | 1 |
| Achanta, S; Balakrishna, S; Brackmann, M; Chintagari, NR; Jordt, SE | 1 |
| Cao, Y; Elmahdy, A; Hui, X; Maibach, H; Zhu, H | 1 |
| Balow, RB; Daniels, GC; Giles, SL; Lundin, JG; McGann, CL; Miranda-Zayas, JL; Wynne, JH | 1 |
| Che, Y; Gong, Y; Xiong, W; Zhao, J | 1 |
| Pal, A; Sabnam, S | 1 |
| Ardestani, SK; Faghihzadeh, S; Ghazanfari, T; Kianmehr, Z; Varmazyar, M | 1 |
| Huang, Q; Jiang, H; Pei, C; Song, T; Wang, F; Xi, H | 1 |
| Bürkle, A; Engbrecht, M; Fischbach, A; Frensch, M; Goly, D; Hakobyan, M; Hefele, T; Mack, M; Mangerich, A; Rank, L; Rossatti, P; Schink, A; Veith, S | 1 |
| Broome, AM; Jiang, YL | 1 |
| Gudermann, T; John, H; Kehe, K; Kranawetvogl, A; Lang, S; Popp, T; Rothmiller, S; Schmidt, A; Siegert, M; Steinritz, D; Thiermann, H | 1 |
| Ghazanfari, T; Hashemi, SM; Mehdi Naghizadeh, M; Mosaffa, N; Sadeghi, S | 1 |
| Pal, A; Pal, S; Rizwan, H; Sabnam, S | 1 |
| Ahmad, A; Ahmad, S; Chandrashekar, DS; Hamid, T; Husain, M; Mariappan, N; Rana, T; Varambally, S; Zafar, I | 1 |
| Cao, R; Chen, Y; Chen, Z; Farha, OK; Goetjen, TA; Hupp, JT; Idrees, KB; Islamoglu, T; Lee, SJ; Li, P; Li, Z; Lyu, J; Mian, MR; Napolitano, A; Peterson, GW; Son, FA; Xia, Q; Zhang, K; Zhang, X | 1 |
| Béal, D; Caffin, F; Douki, T; Eldin, C; Fenaille, F; Gros-Désormeaux, F; Gudimard, L; Junot, C; Léonço, D; Piérard, C; Roser, M | 1 |
| Chehardoli, B; Khamis Abadi, A; Kia, A; Nadi, M; Salimian, J; Shahriary, A | 1 |
| Aghamollaei, H; Haddadi, M; Karami, A; Sabzevare, M; Shahriary, A; Yazdani, F | 1 |
| John, H; Lüling, R; Rein, T; Schmeißer, W; Steinritz, D; Thiermann, H | 1 |
| Béal, D; Caffin, F; Douki, T; Eldin, C; Fenaille, F; Gilardoni, M; Gros-Désormeaux, F; Junot, C; Léonço, D; Ouzia, S; Piérard, C | 1 |
| Cao, R; Cheung, YH; de Koning, MC; Farha, OK; Gong, W; Idrees, KB; Islamoglu, T; Ma, K; Mahle, JJ; Peterson, GW; van Leeuwen, HC; Wang, X; Wasson, MC; Xin, JH | 1 |
| Hajhasan, V; Kia, A; Nadi, M; Salimian, J | 1 |
| Chen, H; Chen, S; Dong, H; Li, W; Liu, S; Liu, W; Lu, F; Wang, L; Wang, Y; Zhang, M; Zhao, J; Zhao, Q; Zhou, S | 1 |
| Caffin, F; Gros-Désormeaux, F; Guatto, N; Igert, A; Piérard, C | 1 |
| Chen, M; Cheng, J; Dan, G; Sai, Y; Wang, B; Ye, F; Yu, W; Zeng, Q; Zhao, J; Zhao, Y; Zou, Z | 1 |
| Chen, D; Guo, L; Jiao, X; Li, C; Qiu, F; Wu, T; Xu, R; Zhao, Q | 1 |
| Feng, W; Liu, XJ; Song, QH; Xue, MJ | 1 |
| Feng, W; Liu, XJ; Song, QH | 1 |
| Chen, M; Cheng, J; Dan, G; Dong, X; Liu, H; Sai, Y; Wang, X; Ye, F; Zou, Z | 1 |
1 review(s) available for 2-chloroethyl ethyl sulfide and mustard gas
| Article | Year |
|---|---|
Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo.
Topics: Acetylcysteine; Animals; Apoptosis; Buthionine Sulfoximine; Cell Cycle; Cell Survival; Cells, Cultured; Dermatitis; DNA; Female; Glutathione; Humans; Mice; Mice, Hairless; Mustard Gas; Peroxidase; Skin; Skinfold Thickness | 2011 |
126 other study(ies) available for 2-chloroethyl ethyl sulfide and mustard gas
| Article | Year |
|---|---|
Supercritical fluid extraction of chemical warfare agent simulants from soil.
Topics: Chemical Warfare Agents; Chromatography, Gas; Chromatography, Liquid; Flame Ionization; Isoflurophate; Mustard Gas; Organophosphorus Compounds; Soil Pollutants | 1992 |
Biosynthesis and urinary excretion of methyl sulfonium derivatives of the sulfur mustard analog, 2-chloroethyl ethyl sulfide, and other thioethers.
Topics: Animals; Chromatography, High Pressure Liquid; Female; Inactivation, Metabolic; Kidney; Liver; Lung; Methylation; Methyltransferases; Mice; Mustard Gas; Substrate Specificity; Sulfides; Sulfonium Compounds | 1990 |
Release of chloroethyl ethyl sulfide-modified DNA bases by bacterial 3-methyladenine-DNA glycosylases I and II.
Topics: Adenine; Alkylating Agents; Alkylation; Chromatography, High Pressure Liquid; DNA; DNA Glycosylases; Escherichia coli; Methylnitrosourea; Mustard Compounds; Mustard Gas; N-Glycosyl Hydrolases | 1989 |
Identification of degradation products of 2-chloroethyl ethyl sulfide by gas chromatography-mass spectrometry.
Topics: Chemical Phenomena; Chemistry; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Mustard Compounds; Mustard Gas; Time Factors | 1988 |
Formation of O6-ethylthioethylguanine in DNA by reaction with the sulfur mustard, chloroethyl sulfide, and its apparent lack of repair by O6-alkylguanine-DNA alkyltransferase.
Topics: Adenine; Alkylation; Animals; Cattle; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; DNA Repair; Guanine; Methyltransferases; Mustard Compounds; Mustard Gas; O(6)-Methylguanine-DNA Methyltransferase | 1986 |
DNA modification by sulfur mustards and nitrosoureas and repair of these lesions.
Topics: Animals; DNA; DNA Repair; Lomustine; Mustard Compounds; Mustard Gas; Mutagens; Structure-Activity Relationship | 1986 |
Formation of O6-ethylthioethyldeoxyguanosine from the reaction of chloroethyl ethyl sulfide with deoxyguanosine.
Topics: Chromatography, High Pressure Liquid; Deoxyguanosine; Indicators and Reagents; Mass Spectrometry; Mustard Compounds; Mustard Gas; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1984 |
Effect of sulfur mustards on lysosomes from rat liver in vitro.
Topics: Acid Phosphatase; Animals; Arylsulfatases; Glucuronidase; In Vitro Techniques; Liver; Lysosomes; Male; Mustard Compounds; Mustard Gas; Rats; Rats, Inbred Strains | 1981 |
Sulphur mustards inhibit binding of transcription factor AP2 in vitro.
Topics: Alkylating Agents; Alkylation; Base Sequence; Binding Sites; Consensus Sequence; Cross-Linking Reagents; DNA-Binding Proteins; Dose-Response Relationship, Drug; Irritants; Molecular Sequence Data; Mustard Gas; Oligonucleotides; Protein Binding; Transcription Factor AP-2; Transcription Factors | 1995 |
Activation of alpha-human tumour necrosis factor (TNF-alpha) by human monocytes (THP-1) exposed to 2-chloroethyl ethyl sulphide (H-MG).
Topics: Cell Line; Free Radicals; Humans; Macrophage Activation; Monocytes; Mustard Gas; Tumor Necrosis Factor-alpha | 1995 |
Protection by lysosomal hydrolase inhibitors against cytotoxicity of 2-chloroethylethyl sulfide.
Topics: Alkylation; Animals; Cell Survival; Cells, Cultured; Drug Interactions; Gentamicins; Kanamycin; Leupeptins; Lysosomes; Mice; Mice, Inbred ICR; Mustard Gas; Oligopeptides; Pepstatins; Phospholipases; Protease Inhibitors; Spleen; Streptomycin; Structure-Activity Relationship; T-Lymphocytes | 1995 |
The release of lysosomal arylsulfatase from liver lysosomes exposed to 2-chloroethylethyl sulfide.
Topics: Animals; Arylsulfatases; Calcium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glucuronidase; Hydrogen-Ion Concentration; Intracellular Membranes; Liver; Lysosomes; Magnesium; Male; Manganese; Mice; Mice, Inbred ICR; Mustard Gas; Propane | 1995 |
Inactivation of microsomal Ca(2+)-ATPase by 2-chloroethylethyl sulfide.
Topics: Adenosine Triphosphate; Alkylation; Animals; Binding Sites; Calcium; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kinetics; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; Mustard Gas; Octoxynol; Temperature | 1995 |
Exposure of human lymphocytes to bis-(2-chloroethyl)sulfide solubilizes truncated and intact core histones.
Topics: Amino Acid Sequence; Cell Division; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Histones; Humans; Lymphocytes; Molecular Sequence Data; Mustard Gas; Solubility | 1994 |
Change in glutathione S-transferase and glyceraldehyde-3-phosphate dehydrogenase activities in the organs of mice treated with 2-chloroethyl ethyl sulfide or its oxidation products.
Topics: Animals; Enzyme Activation; Glutathione Transferase; Glyceraldehyde-3-Phosphate Dehydrogenases; Liver; Lung; Male; Mice; Mice, Inbred ICR; Mice, Nude; Mustard Gas; Organ Specificity; Oxidation-Reduction; Spleen | 1996 |
Apoptosis as a mechanism of 2-chloroethylethyl sulfide-induced cytotoxicity.
Topics: Animals; Apoptosis; Cell Nucleus; Cells, Cultured; Chromatin; Cycloheximide; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Enzyme-Linked Immunosorbent Assay; Genetic Techniques; Immunohistochemistry; Mice; Mice, Inbred ICR; Mustard Gas; Nucleosomes; Protein Synthesis Inhibitors; Thymus Gland | 1998 |
Corneal damage by half mustard (2-chloroethyl ethyl sulfide, CEES) in vitro preventive studies: a histologic and electron microscopic evaluation.
Topics: Animals; Antioxidants; Chemical Warfare Agents; Cornea; Corneal Opacity; Drug Combinations; In Vitro Techniques; Ketoglutaric Acids; Mustard Gas; Pantothenic Acid; Pyruvic Acid; Rabbits; Taurine | 1998 |
Half mustard (CEES) induced damage to rabbit cornea: attenuating effect of taurine-pyruvate-alpha-ketoglutarate-pantothenate mixture.
Topics: Animals; Chemical Warfare Agents; Cornea; Corneal Opacity; Drug Combinations; In Vitro Techniques; Ketoglutaric Acids; Mustard Gas; Pantothenic Acid; Pyruvic Acid; Rabbits; Rubidium; Taurine | 1998 |
Il-1-related cytokine responses of nonimmune skin cells subjected to CEES exposure with and without potential vesicant antagonists.
Topics: Benzimidazoles; Biomarkers; Calmodulin; Cells, Cultured; Cysteine Proteinase Inhibitors; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Humans; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Irritants; Keratinocytes; Leupeptins; Mustard Gas; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Receptors, Interleukin-1; Receptors, Interleukin-1 Type II; Sialoglycoproteins | 2000 |
Repair of sulfur mustard-induced DNA damage in mammalian cells measured by a host cell reactivation assay.
Topics: Animals; Cell Survival; CHO Cells; Coleoptera; Cricetinae; Dermatologic Agents; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Genetic Techniques; Luciferases; Luminescent Measurements; Models, Chemical; Mustard Gas; Plasmids; Transfection | 2001 |
Effects of CEES on inflammatory mediators, heat shock protein 70A, histology and ultrastructure in two skin models.
Topics: Biomarkers; Blister; Cell Culture Techniques; Cytokines; Dermatologic Agents; HSP70 Heat-Shock Proteins; Humans; Inflammation; Keratinocytes; Models, Biological; Mustard Gas; Skin; Skin, Artificial | 2000 |
MALDI-ToF/MS as a diagnostic tool for the confirmation of sulfur mustard exposure.
Topics: Acetonitriles; Animals; Dermatologic Agents; Hemoglobins; Humans; Metallothionein; Mustard Gas; Poisoning; Rabbits; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2000 |
Reactivity of chloroethyl sulfides in the presence of a chlorinated prophylactic: a kinetic study by EPR/spin trapping and NMR techniques.
Topics: Amides; Carbon Isotopes; Dermatologic Agents; Electron Spin Resonance Spectroscopy; Kinetics; Magnetic Resonance Spectroscopy; Mustard Gas; Organic Chemicals; Oxidation-Reduction; Protective Agents; Spin Trapping | 2000 |
Ultrastructural and histological effects of exposure to CEES or heat in a human epidermal model.
Topics: Apoptosis; DNA; DNA Damage; Epidermis; Hot Temperature; Humans; In Situ Nick-End Labeling; Keratinocytes; Microscopy, Electron; Mustard Gas; Organ Culture Techniques; Organelles | 2001 |
Lipopolysaccharide enhances the cytotoxicity of 2-chloroethyl ethyl sulfide.
Topics: Adjuvants, Immunologic; Animals; Cell Death; Cell Line; Chemical Warfare Agents; Cytokines; Drug Synergism; Interleukin-1; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mustard Gas; Propidium; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Time Factors; Tumor Necrosis Factor-alpha | 2003 |
Signal transduction events in lung injury induced by 2-chloroethyl ethyl sulfide, a mustard analog.
Topics: Administration, Inhalation; Animals; Apoptosis; Caspases; Ceramides; Electrophoretic Mobility Shift Assay; Guinea Pigs; Intubation, Intratracheal; Lung; Lung Diseases; Male; Mustard Gas; NF-kappa B; Signal Transduction; Sphingomyelin Phosphodiesterase; Tumor Necrosis Factor-alpha | 2003 |
Photocatalytic oxidation of gaseous 2-chloroethyl ethyl sulfide over TiO2.
Topics: Catalysis; Coloring Agents; Environmental Pollutants; Gases; Mustard Gas; Oxidation-Reduction; Photochemistry; Titanium | 2003 |
Sequence specificity of DNA alkylation by the antitumor natural product leinamycin.
Topics: Alkylation; Animals; Antineoplastic Agents, Alkylating; Base Sequence; Binding Sites; Cattle; DNA; DNA, Single-Stranded; Fishes; Guanine; Lactams; Macrolides; Male; Molecular Sequence Data; Mustard Gas; Oligonucleotides; Perchlorates; Phosphoric Monoester Hydrolases; Plasmids; Sodium Compounds; Spermatozoa; Substrate Specificity; Sulfuric Acid Esters; Thiazoles; Thiones | 2003 |
Protection by antioxidants against toxicity and apoptosis induced by the sulphur mustard analog 2-chloroethylethyl sulphide (CEES) in Jurkat T cells and normal human lymphocytes.
Topics: Antioxidants; Apoptosis; Cell Survival; Humans; Jurkat Cells; Lymphocytes; Mustard Gas; Reactive Oxygen Species | 2004 |
Evidence of hair loss after subacute exposure to 2-chloroethyl ethyl sulfide, a mustard analog, and beneficial effects of N-acetyl cysteine.
Topics: Acetylcysteine; Alopecia; Animals; Biomarkers; Guinea Pigs; Hair; Mustard Gas; Toxicity Tests, Acute | 2004 |
Genomic analysis of rodent pulmonary tissue following bis-(2-chloroethyl) sulfide exposure.
Topics: Animals; Chemical Warfare Agents; Dose-Response Relationship, Drug; Gene Expression Profiling; Genes, cdc; Genes, p53; Genomics; Injections, Intravenous; Lung; Male; Mustard Gas; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2005 |
Preparation and application of the sol-gel-derived acrylate/silicone co-polymer coatings for headspace solid-phase microextraction of 2-chloroethyl ethyl sulfide in soil.
Topics: Acrylates; Chemical Warfare Agents; Gels; Mustard Gas; Polymers; Reference Standards; Reproducibility of Results; Silicones; Soil Pollutants; Spectrophotometry, Infrared | 2005 |
[Photocatalytic removing of a mustard gas analogue 2-CEES vapor over SO4(2-)/TiO2].
Topics: Air Pollutants; Air Pollution; Catalysis; Chemical Warfare Agents; Mustard Gas; Photochemistry; Sulfur Dioxide; Sulfuric Acids; Titanium | 2005 |
Decrease in brain POMC mRNA expression and onset of obesity in guinea pigs exposed to 2-chloroethyl ethyl sulfide, a mustard analogue.
Topics: Animals; Body Weight; Brain; Chemical Warfare Agents; Down-Regulation; Guinea Pigs; Male; Mustard Gas; Obesity; Pro-Opiomelanocortin; RNA, Messenger | 2006 |
Inhibition of cholinephosphotransferase activity in lung injury induced by 2-chloroethyl ethyl sulfide, a mustard analog.
Topics: Animals; Base Sequence; Blotting, Northern; Ceramides; Diacylglycerol Cholinephosphotransferase; DNA Primers; Enzyme Inhibitors; Guinea Pigs; Lung; Male; Microscopy, Electron; Microsomes; Mustard Gas; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Surface-enhanced Raman spectroscopy of half-mustard agent.
Topics: Air Pollutants; Chemical Warfare Agents; Environmental Monitoring; Equipment Design; Humans; Mustard Gas; Nanotechnology; Spectrum Analysis, Raman; Surface Properties | 2006 |
Modulation of the expression of superoxide dismutase gene in lung injury by 2-chloroethyl ethyl sulfide, a mustard analog.
Topics: Animals; Gene Expression Regulation, Enzymologic; Guinea Pigs; Lung; Lung Diseases; Male; Mustard Gas; RNA, Messenger; Superoxide Dismutase | 2006 |
Inhibition of inducible Nitric Oxide Synthase by a mustard gas analog in murine macrophages.
Topics: Animals; Cell Line; Enzyme Inhibitors; Kinetics; Lipopolysaccharides; Macrophages; Mice; Mustard Gas; Nitric Oxide Synthase Type II | 2006 |
Base excision repair sensitizes cells to sulfur mustard and chloroethyl ethyl sulfide.
Topics: Animals; Cell Survival; DNA Damage; DNA Glycosylases; DNA Repair; Escherichia coli; Luciferases; Models, Chemical; Models, Molecular; Molecular Conformation; Mustard Gas; Mutagenesis | 2007 |
A dorsal model for cutaneous vesicant injury by 2-chloroethyl ethyl sulfide using C57BL/6 mice.
Topics: Animals; Body Weight; Chemical Warfare Agents; Dermatitis; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Erythema; Irritants; Male; Mice; Mice, Inbred C57BL; Motor Activity; Mustard Gas; Necrosis; Severity of Illness Index; Skin Pigmentation; Time Factors; Wound Healing | 2007 |
Detection of chemical weapon agents and simulants using chemical ionization reaction time-of-flight mass spectrometry.
Topics: Breath Tests; Calibration; Environmental Monitoring; Humidity; Molecular Structure; Mustard Gas; Organophosphates; Organophosphorus Compounds; Reproducibility of Results; Sarin; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors | 2007 |
Ability of antioxidant liposomes to prevent acute and progressive pulmonary injury.
Topics: Acetylcysteine; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Chemokines; Cytokines; Free Radical Scavengers; Humans; Liposomes; Lung; Macrophages, Alveolar; Male; Mustard Gas; Rats; Rats, Long-Evans; Respiratory Distress Syndrome; Tocopherols | 2008 |
The influence of N-acetyl-L-cysteine on oxidative stress and nitric oxide synthesis in stimulated macrophages treated with a mustard gas analogue.
Topics: Acetylcysteine; Animals; Cell Survival; Free Radical Scavengers; Glutathione; Lipopolysaccharides; Macrophages; Mice; Microscopy, Fluorescence; Mustard Gas; Nitric Oxide; Oxidative Stress; Polymyxin B | 2008 |
Activation of MAPK/AP-1 signaling pathway in lung injury induced by 2-chloroethyl ethyl sulfide, a mustard gas analog.
Topics: Animals; Blotting, Western; Cyclin D1; DNA; Guinea Pigs; Lung; Male; MAP Kinase Signaling System; Mustard Gas; Proliferating Cell Nuclear Antigen; Signal Transduction; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2008 |
Kinetics of ion-molecule reactions with 2-chloroethyl ethyl sulfide at 298 K: a search for CIMS schemes for mustard gas.
Topics: Chemical Warfare Agents; Ions; Kinetics; Mustard Gas; Spectrometry, Mass, Electrospray Ionization; Temperature | 2008 |
Reduction of vesicant toxicity by butylated hydroxyanisole in A-431 skin cells.
Topics: Antioxidants; Azoles; Buthionine Sulfoximine; Butylated Hydroxyanisole; Cell Line, Tumor; Chemical Warfare Agents; DNA Fragmentation; Epidermal Cells; Glutathione; Humans; Isoindoles; Mechlorethamine; Molecular Structure; Mustard Gas; Organoselenium Compounds | 2008 |
A role for mitochondrial oxidative stress in sulfur mustard analog 2-chloroethyl ethyl sulfide-induced lung cell injury and antioxidant protection.
Topics: Antioxidants; Cell Survival; Epithelial Cells; Humans; Lung Injury; Mitochondria; Mitochondrial Membranes; Mustard Gas; Oxidative Stress; Reactive Oxygen Species | 2009 |
Inflammatory biomarkers of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced skin injury in SKH-1 hairless mice.
Topics: Administration, Topical; Analysis of Variance; Animals; Apoptosis; Biomarkers, Pharmacological; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Epidermis; Female; Inflammation; Mast Cells; Mice; Mice, Hairless; Mustard Gas; Neutrophil Infiltration; Peroxidase; Proliferating Cell Nuclear Antigen; Random Allocation; Skin | 2009 |
DNA damage, signalling and repair after exposure of cells to the sulphur mustard analogue 2-chloroethyl ethyl sulphide.
Topics: Ataxia Telangiectasia Mutated Proteins; Blotting, Western; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Checkpoint Kinase 2; Comet Assay; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Humans; Multienzyme Complexes; Mustard Gas; Phosphodiesterase I; Phosphoric Diester Hydrolases; Phosphorylation; Protein Serine-Threonine Kinases; Pyrophosphatases; Signal Transduction; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2009 |
Kinetics of adsorption of 2-chloroethylethylsulphide on Al2O3 nanoparticles with and without impregnants.
Topics: Adsorption; Aluminum Oxide; Chemical Warfare Agents; Decontamination; Halogenation; Hydrolysis; Kinetics; Mustard Gas; Nanoparticles | 2009 |
Role of MAPK/AP-1 signaling pathway in the protection of CEES-induced lung injury by antioxidant liposome.
Topics: Acetylcysteine; Activating Transcription Factors; Animals; Antidotes; Antioxidants; Blood Proteins; Cell Proliferation; Cyclin D1; Disease Models, Animal; Erythrocytes; Guinea Pigs; Liposomes; Lung; Lung Injury; Male; Mitogen-Activated Protein Kinases; Mustard Gas; Neutrophil Infiltration; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pulmonary Eosinophilia; Time Factors; Tocopherols; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2009 |
Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice.
Topics: Aldehydes; Animals; Cyclic N-Oxides; Deoxyadenosines; Dermatitis, Irritant; DNA Damage; Female; MAP Kinase Signaling System; Mice; Mice, Hairless; Mustard Gas; NF-kappa B; Oncogene Protein v-akt; Oxidation-Reduction; Oxidative Phosphorylation; Oxidative Stress; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Skin; Transcription Factor AP-1; Transcriptional Activation | 2009 |
Direct binding of sulfur mustard and chloroethyl ethyl sulphide to human cell membrane-associated proteins; implications for sulfur mustard pathology.
Topics: Actins; Annexin A2; Carbon Isotopes; Cell Fractionation; Cell Line, Transformed; Chemical Warfare Agents; Electrophoresis, Gel, Two-Dimensional; Humans; Membrane Proteins; Mustard Gas; Peptide Fragments; Peptide Mapping; Protein Binding | 2010 |
2,6-Dithiopurine blocks toxicity and mutagenesis in human skin cells exposed to sulfur mustard analogues, 2-chloroethyl ethyl sulfide and 2-chloroethyl methyl sulfide.
Topics: Cell Line, Tumor; Cell Survival; Cytotoxins; Humans; Mustard Gas; Mutagenesis; Purines; Skin; Sulfides | 2010 |
Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.
Topics: Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Inflammation; Inhalation Exposure; L-Lactate Dehydrogenase; Lung; Male; Metalloporphyrins; Mustard Gas; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley | 2010 |
Selective targeting of selenocysteine in thioredoxin reductase by the half mustard 2-chloroethyl ethyl sulfide in lung epithelial cells.
Topics: Amino Acid Motifs; Animals; Cell Line, Tumor; Epithelial Cells; Humans; Lung; Mustard Gas; Mutant Proteins; Oxidation-Reduction; Rats; Recombinant Proteins; Selenocysteine; Thioredoxin-Disulfide Reductase | 2010 |
Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell cycle checkpoint pathway.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Caspase 3; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Line; Cell Survival; DNA; DNA-Binding Proteins; Epidermal Cells; Humans; Mice; Mustard Gas; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Skin; Tumor Suppressor Proteins | 2010 |
Inhibition of NADPH cytochrome P450 reductase by the model sulfur mustard vesicant 2-chloroethyl ethyl sulfide is associated with increased production of reactive oxygen species.
Topics: Animals; Cells, Cultured; Cytochrome P-450 CYP1A1; Irritants; Mustard Gas; NADPH-Ferrihemoprotein Reductase; Rats; Reactive Oxygen Species | 2010 |
Expression of proliferative and inflammatory markers in a full-thickness human skin equivalent following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.
Topics: Biomarkers; Blotting, Western; Cell Proliferation; Dose-Response Relationship, Drug; Eicosanoids; Histones; Humans; Irritants; Keratinocytes; Mustard Gas; Poly Adenosine Diphosphate Ribose; Proliferating Cell Nuclear Antigen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Time Factors | 2010 |
Protective actions of des-aspartate-angiotensin I in mice model of CEES-induced lung intoxication.
Topics: Angiotensin I; Animals; Bronchoalveolar Lavage Fluid; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Epoprostenol; Intercellular Adhesion Molecule-1; Losartan; Lung; Male; Mice; Mice, Inbred BALB C; Mustard Gas; NADPH Oxidases; Peroxidase; Reactive Oxygen Species; Receptors, Immunologic; Signal Transduction | 2011 |
Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.
Topics: Animals; Bronchoalveolar Lavage Fluid; Irritants; Lung; Lung Injury; Male; Mice; Mice, Knockout; Mustard Gas; Oxidative Stress; Receptors, Tumor Necrosis Factor, Type I; Tumor Necrosis Factor-alpha | 2011 |
2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin.
Topics: Animals; Blister; Chemical Warfare Agents; Dermatitis, Contact; Disease Models, Animal; Immunohistochemistry; Male; Mast Cells; Mice; Mice, Hairless; Mustard Gas; Organ Size; Peroxidase; Skin | 2011 |
Sodium pyruvate modulates cell death pathways in HaCaT keratinocytes exposed to half-mustard gas.
Topics: Antioxidants; Apoptosis; Biomarkers; Cells, Cultured; DNA Damage; Drug Combinations; Humans; Inflammation; Keratinocytes; Liposomes; Mustard Gas; Necrosis; Oxidative Stress; Pyruvates; Skin | 2011 |
Investigation of anticholinergic and non-steroidal anti-inflammatory prodrugs which reduce chemically induced skin inflammation.
Topics: Acetylcholinesterase; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Warfare Agents; Cholinergic Antagonists; Cholinesterase Inhibitors; Disease Models, Animal; Ear; Female; Humans; Inflammation; Irritants; Mice; Mustard Gas; Prodrugs; Skin; Tetradecanoylphorbol Acetate | 2012 |
Significance of porous structure on degradatin of 2,2' dichloro diethyl sulphide and 2 chloroethyl ethyl sulphide on the surface of vanadium oxide nanostructure.
Topics: Chemical Warfare Agents; Hydrolysis; Kinetics; Molecular Structure; Mustard Gas; Nanostructures; Oxidation-Reduction; Oxides; Porosity; Vanadium Compounds | 2011 |
Regulation of Hsp27 and Hsp70 expression in human and mouse skin construct models by caveolae following exposure to the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.
Topics: Animals; Caveolae; Caveolin 1; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; MAP Kinase Signaling System; Mice; Molecular Chaperones; Mustard Gas; Skin | 2011 |
Facility monitoring of chemical warfare agent simulants in air using an automated, field-deployable, miniature mass spectrometer.
Topics: Air; Chemical Warfare Agents; Malonates; Miniaturization; Models, Chemical; Mustard Gas; Organophosphorus Compounds; ROC Curve; Salicylates; Sensitivity and Specificity; Tandem Mass Spectrometry | 2011 |
Role of reactive oxygen and nitrogen species in olfactory epithelial injury by the sulfur mustard analogue 2-chloroethyl ethyl sulfide.
Topics: Administration, Inhalation; Animals; Antioxidants; Apoptosis; Blotting, Western; Cell Proliferation; Epithelial Cells; Immunoenzyme Techniques; Male; Metalloporphyrins; Mustard Gas; Nasal Cavity; Nitric Oxide Synthase Type II; Olfactory Mucosa; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Reactive Oxygen Species | 2011 |
Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin.
Topics: Alkylating Agents; Animals; Antidotes; Blister; Chemical Warfare Agents; Cyclooxygenase 2; Dermatitis, Contact; DNA Damage; Female; Glutathione; Histones; Inflammation Mediators; Male; Matrix Metalloproteinase 9; Mice; Mice, Hairless; Mustard Gas; Nitric Oxide Synthase Type II; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Skin | 2011 |
Protection against 2-chloroethyl ethyl sulfide (CEES)-induced cytotoxicity in human keratinocytes by an inducer of the glutathione detoxification pathway.
Topics: Blotting, Western; Cell Line; Cell Survival; Chemical Warfare Agents; Drug Interactions; Epidermal Cells; Epidermis; Glutathione; Humans; Inactivation, Metabolic; Keratinocytes; Mustard Gas; NF-E2-Related Factor 2; Oleanolic Acid | 2011 |
Induction of neuronal damage in guinea pig brain by intratracheal infusion of 2-chloroethyl ethyl sulfide, a mustard gas analog.
Topics: alpha-Synuclein; Animals; Brain; Brain Injuries; Chemical Warfare Agents; Dopamine Plasma Membrane Transport Proteins; Erythrocytes; Gene Expression Regulation; Guinea Pigs; Lung; Male; Mustard Gas; Oxidative Stress; Permeability; Tissue Distribution; Trachea | 2012 |
Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts.
Topics: Animals; Cell Line; Chromans; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Glutathione; Histones; Mice; Mice, Hairless; Mustard Gas; Oxidation-Reduction; Phosphorylation; Reactive Oxygen Species; Skin; Structure-Activity Relationship; Tumor Suppressor Protein p53 | 2011 |
Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide.
Topics: Airway Obstruction; Animals; Antigens, Surface; Bronchi; Bronchoalveolar Lavage Fluid; Cell Line, Transformed; Chemical Warfare Agents; Disease Models, Animal; Epithelial Cells; Factor VII; Factor Xa; Humans; Inhalation Exposure; Male; Milk Proteins; Mustard Gas; Proteins; Rats; Rats, Sprague-Dawley; Thromboplastin; Time Factors | 2012 |
Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning.
Topics: Acute-Phase Proteins; Animals; Chemical Warfare Agents; Female; Gene Expression Regulation; Inflammation; Lipocalin-2; Lipocalins; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Mice, Knockout; Mustard Gas; Nitric Oxide Synthase Type II; Oncogene Proteins; Oxidative Stress; Reactive Nitrogen Species; Time Factors; Tumor Necrosis Factor-alpha | 2012 |
2,6-Dithiopurine, a nucleophilic scavenger, protects against mutagenesis in mouse skin treated in vivo with 2-(chloroethyl) ethyl sulfide, a mustard gas analog.
Topics: Administration, Cutaneous; Animals; Chemical Warfare Agents; DNA Damage; Dose-Response Relationship, Drug; Female; Genetic Engineering; Histones; Keratin-6; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Mustard Gas; Mutagenesis; Mutation; Phosphorylation; Purines; Skin; Time Factors | 2012 |
Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Antidotes; Apoptosis; Cells, Cultured; Chemical Warfare Agents; Cyclooxygenase 2; Deoxyguanosine; DNA Damage; Female; Gene Expression Regulation; Humans; Inflammation; Matrix Metalloproteinase 9; Mice; Mice, Hairless; Mustard Gas; Nitric Oxide Synthase Type II; Oxidative Stress; Signal Transduction; Silybin; Silymarin; Skin | 2012 |
Sulforaphane induces phase II detoxication enzymes in mouse skin and prevents mutagenesis induced by a mustard gas analog.
Topics: Animals; Chemical Warfare Agents; Enzyme Induction; Female; Glutamate-Cysteine Ligase; Glutathione; Glutathione Transferase; Immunoblotting; Isothiocyanates; Mice; Mice, Inbred C57BL; Mustard Gas; Mutation; Skin; Sulfoxides; Thiocyanates | 2013 |
Ebselen analogues reduce 2-chloroethyl ethyl sulphide toxicity in A-431 cells.
Topics: Antioxidants; Azoles; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Chemical Warfare Agents; Humans; Isoindoles; Mustard Gas; Organoselenium Compounds; Oxidative Stress; Protective Agents; Resveratrol; Stilbenes | 2013 |
Tissue factor pathway inhibitor prevents airway obstruction, respiratory failure and death due to sulfur mustard analog inhalation.
Topics: Administration, Inhalation; Airway Obstruction; Animals; Blotting, Western; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Enzyme-Linked Immunosorbent Assay; Fibrin; Fibrinolysis; Immunoglobulin M; Immunohistochemistry; Indicators and Reagents; Lipoproteins; Male; Microdissection; Mustard Gas; Proteins; Prothrombin; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Respiratory Insufficiency | 2013 |
Mechanistic insights into the hydrolysis of 2-chloroethyl ethyl sulfide: the expanded roles of sulfonium salts.
Topics: Hydrolysis; Kinetics; Molecular Structure; Mustard Gas; Salts; Sulfonium Compounds | 2013 |
Modified immunoslotblot assay to detect hemi and sulfur mustard DNA adducts.
Topics: Cell Line; Chemical Warfare Agents; DNA Adducts; DNA Damage; Humans; Immunoblotting; Keratinocytes; Mechlorethamine; Mustard Gas; Skin | 2013 |
Ameliorating effect of S-2(ω-aminoalkylamino) alkylaryl sulfide (DRDE-07) on sulfur mustard analogue, 2-chloroethyl ethyl sulfide-induced oxidative stress and inflammation.
Topics: Administration, Cutaneous; Amifostine; Animals; Anti-Inflammatory Agents; Chemical Warfare Agents; Glutathione; Interleukins; Lethal Dose 50; Lipid Peroxidation; Liver; Lung; Male; Malondialdehyde; Mice; Mustard Gas; Oxidative Stress; Skin | 2013 |
Physics-based agent to simulant correlations for vapor phase mass transport.
Topics: Air Pollutants; Chemical Warfare Agents; Decontamination; Diffusion; Environmental Monitoring; Environmental Restoration and Remediation; Gases; Malonates; Models, Theoretical; Molecular Weight; Mustard Gas; Particle Size; Reproducibility of Results; Salicylates; Sulfides; Temperature | 2013 |
Optical "Turn off" based selective detection and concomitant degradation of 2-chloroethyl ethyl sulfide (CEES) via Mg-porphyrazine complex immobilized on glass.
Topics: Glass; Limit of Detection; Magnesium; Mustard Gas; Spectrophotometry, Ultraviolet | 2014 |
Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog.
Topics: Animals; Blood Coagulation Tests; Bronchitis; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Drug Administration Routes; Erythrocytes; Fibrinolytic Agents; Heparin; Models, Animal; Mustard Gas; Oxygen; Rats, Sprague-Dawley; Trachea | 2015 |
Antifibrinolytic mechanisms in acute airway injury after sulfur mustard analog inhalation.
Topics: Acute Lung Injury; Airway Obstruction; alpha-2-Antiplasmin; Animals; Antifibrinolytic Agents; Blood-Air Barrier; Bronchoalveolar Lavage Fluid; Capillary Permeability; Carboxypeptidase B2; Chemical Warfare Agents; Fibrinolysis; Inhalation Exposure; Lung; Male; Mustard Gas; Plasminogen Activator Inhibitor 1; Rats, Sprague-Dawley; Time Factors | 2014 |
Catalytic antioxidant AEOL 10150 treatment ameliorates sulfur mustard analog 2-chloroethyl ethyl sulfide-associated cutaneous toxic effects.
Topics: Animals; Antidotes; Antioxidants; Cell Line; Cell Proliferation; Cell Survival; Chemical Warfare Agents; Comet Assay; Humans; Metalloporphyrins; Mice; Mice, Hairless; Mustard Gas; Oxidative Stress; Skin | 2014 |
Mustard gas surrogate, 2-chloroethyl ethylsulfide (2-CEES), induces centrosome amplification and aneuploidy in human and mouse cells : 2-CEES induces centrosome amplification and chromosome instability.
Topics: Aneuploidy; Animals; Cell Line, Tumor; Cell Survival; Centrosome; Chemical Warfare Agents; Chromosomal Instability; Humans; Mice; Mustard Gas; NIH 3T3 Cells | 2014 |
Effects of CEES and LPS synergistically stimulate oxidative stress inactivates OGG1 signaling in macrophage cells.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Catalase; Cell Cycle; Cell Line; Cell Survival; Chemical Warfare Agents; Deoxyguanosine; DNA Damage; DNA Glycosylases; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinases; Mustard Gas; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Superoxide Dismutase; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2014 |
Activation of the chemosensing transient receptor potential channel A1 (TRPA1) by alkylating agents.
Topics: Alkylating Agents; Calcium; Calcium Channels; Cell Line; Chemical Warfare Agents; Epithelial Cells; HEK293 Cells; Humans; Lung; Mustard Gas; Nerve Tissue Proteins; Oximes; Transient Receptor Potential Channels; TRPA1 Cation Channel | 2015 |
The chemiluminescence determination of 2-chloroethyl ethyl sulfide using luminol-AgNO3-silver nanoparticles system.
Topics: Chemical Warfare Agents; Limit of Detection; Luminescent Agents; Luminescent Measurements; Luminol; Mustard Gas; Nanoparticles; Signal-To-Noise Ratio; Silver Nitrate; Water Pollutants, Chemical | 2015 |
Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences.
Topics: Adenosine Diphosphate Ribose; Antidotes; Antineoplastic Agents, Alkylating; Cell Line; Cell Proliferation; Cell Survival; Chemical Warfare Agents; Chlorambucil; DNA Adducts; Dose-Response Relationship, Drug; Drug Synergism; Genomic Instability; Humans; Keratinocytes; Mechlorethamine; Micronuclei, Chromosome-Defective; Mustard Gas; Nitrogen Mustard Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Signal Transduction; Time Factors | 2016 |
Immunochemical analysis of poly(ADP-ribosyl)ation in HaCaT keratinocytes induced by the mono-alkylating agent 2-chloroethyl ethyl sulfide (CEES): Impact of experimental conditions.
Topics: Adenosine Diphosphate Ribose; Antidotes; Cell Line; Chemical Warfare Agents; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; Keratinocytes; Mustard Gas; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; RNA Interference; Time Factors; Transfection | 2016 |
Efficacy of scalp hair decontamination following exposure to vapours of sulphur mustard simulants 2-chloroethyl ethyl sulphide and methyl salicylate.
Topics: Aluminum Compounds; Chemical Warfare Agents; Decontamination; Gas Chromatography-Mass Spectrometry; Gases; Hair; Magnesium Compounds; Mustard Gas; Salicylates; Silicates; Skin Cream | 2017 |
Increasing NO level regulates apoptosis and inflammation in macrophages after 2-chloroethyl ethyl sulphide challenge.
Topics: Animals; Antioxidants; Apoptosis; Cell Cycle Checkpoints; Cell Line; DNA Damage; Humans; Inflammation; Inflammation Mediators; Lipid Peroxidation; Macrophages; Mice; Mice, Hairless; Mustard Gas; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; RAW 264.7 Cells; RNA, Messenger | 2017 |
Cognitive and emotional impairments after cutaneous intoxication by CEES (a sulfur mustard analog) in mice.
Topics: Administration, Cutaneous; Administration, Topical; Affective Symptoms; Animals; Anxiety; Chemical Warfare Agents; Cognition Disorders; DNA Damage; Erythema; Male; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mustard Gas; Skin | 2018 |
Immediate responses of the cockroach Blaptica dubia after the exposure to sulfur mustard.
Topics: Alkylating Agents; Animals; Arthropod Antennae; Behavior, Animal; Chemical Warfare Agents; Cockroaches; Dose-Response Relationship, Drug; Electrophysiology; Extremities; Flight, Animal; Ganglia, Invertebrate; Mustard Gas | 2018 |
Desorption of sulphur mustard simulants methyl salicylate and 2-chloroethyl ethyl sulphide from contaminated scalp hair after vapour exposure.
Topics: Chemical Warfare Agents; Environmental Exposure; Gases; Hair; Kinetics; Mustard Gas; Salicylates; Scalp | 2018 |
TRPA1 and CGRP antagonists counteract vesicant-induced skin injury and inflammation.
Topics: Acetanilides; Animals; Biomarkers; Blister; Calcitonin Gene-Related Peptide; Chemical Warfare Agents; Cytokines; Ear, External; Keratinocytes; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mustard Gas; Purines; Pyridines; Skin; Skin Diseases; Spiro Compounds; TRPA1 Cation Channel | 2018 |
In vitro human skin permeation and decontamination of 2-chloroethyl ethyl sulfide (CEES) using Dermal Decontamination Gel (DDGel) and Reactive Skin Decontamination Lotion (RSDL).
Topics: Aged; Chemical Warfare Agents; Decontamination; Dermis; Epidermis; Gels; Humans; In Vitro Techniques; Male; Mustard Gas; Skin Absorption | 2018 |
Air Activated Self-Decontaminating Polydicyclopentadiene PolyHIPE Foams for Rapid Decontamination of Chemical Warfare Agents.
Topics: Chemical Warfare Agents; Chromatography, Liquid; Decontamination; Disulfoton; Emulsions; Hydrogen Peroxide; Indenes; Mass Spectrometry; Mustard Gas; Oxidation-Reduction; Polymers; Porosity; Styrenes; Time Factors | 2018 |
Sensitive Discrimination of Nerve Agent and Sulfur Mustard Simulants Using Fluorescent Coassembled Nanofibers with Förster Resonance Energy Transfer-Enhanced Photostability and Emission.
Topics: Carbazoles; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Limit of Detection; Mustard Gas; Nanofibers; Nerve Agents; Organophosphorus Compounds; Ultraviolet Rays | 2019 |
Relevance of Erk1/2-PI3K/Akt signaling pathway in CEES-induced oxidative stress regulates inflammation and apoptosis in keratinocytes.
Topics: Animals; Antioxidants; Apoptosis; Chemical Warfare Agents; DNA Damage; Glutathione; Inflammation; Keratinocytes; Lipid Peroxidation; MAP Kinase Signaling System; Mice; Mice, Hairless; Mitogen-Activated Protein Kinases; Mustard Gas; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction | 2019 |
Time course study of oxidative stress in sulfur mustard analog 2‑chloroethyl ethyl sulfide-induced toxicity.
Topics: Animals; Injections, Intraperitoneal; Lethal Dose 50; Liver; Lung; Male; Mice, Inbred BALB C; Mustard Gas; Oxidative Stress; Time Factors | 2019 |
Bacillus subtilis Spore Surface Display of Haloalkane Dehalogenase DhaA.
Topics: Bacillus subtilis; Bacterial Proteins; Enzyme Stability; Gene Expression; Hydrolases; Mustard Gas; Recombinant Fusion Proteins; Rhodococcus; Spores, Bacterial; Substrate Specificity | 2019 |
PARP1 regulates DNA damage-induced nucleolar-nucleoplasmic shuttling of WRN and XRCC1 in a toxicant and protein-specific manner.
Topics: Camptothecin; Cell Nucleolus; Cell Nucleus; DNA Damage; Gossypol; HeLa Cells; Humans; Hydrogen Peroxide; Mustard Gas; Poly (ADP-Ribose) Polymerase-1; Protein Binding; Protein Transport; Werner Syndrome Helicase; X-ray Repair Cross Complementing Protein 1 | 2019 |
Novel Pyrene Excimer and Fluorogenic Probe for the Detection of Alkylating Agents.
Topics: Alkylating Agents; Antineoplastic Agents; Busulfan; Chemical Warfare Agents; Fluorescent Dyes; Mustard Gas; Pipobroman; Pyrenes; Salicylates; Spectrometry, Fluorescence; Temozolomide | 2019 |
Skin sensitizing effects of sulfur mustard and other alkylating agents in accordance to OECD guidelines.
Topics: Biomarkers; Chemical Warfare Agents; Chlorambucil; Guidelines as Topic; Humans; Irritants; Keratinocytes; Langerhans Cells; Mechlorethamine; Mustard Gas; Risk Assessment; Skin; Skin Irritancy Tests | 2019 |
The immunomodulatory effects of mesenchymal stem cells on long term pulmonary complications in an animal model exposed to a sulfur mustard analog.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cell Differentiation; Chemical Warfare Agents; Cytokines; Disease Models, Animal; Immunologic Factors; Lung; Lung Diseases; Macrophages, Alveolar; Male; Mesenchymal Stem Cells; Mice, Inbred C57BL; Mustard Gas | 2020 |
CEES-induced ROS accumulation regulates mitochondrial complications and inflammatory response in keratinocytes.
Topics: Animals; Cell Line; Chemical Warfare Agents; DNA Damage; DNA, Mitochondrial; Humans; Inflammation; Irritants; Keratinocytes; Membrane Potential, Mitochondrial; Mice; Mice, Hairless; Mitochondria; Mustard Gas; Oxidative Stress; Reactive Oxygen Species; Signal Transduction | 2020 |
MicroRNA-mediated inflammation and coagulation effects in rats exposed to an inhaled analog of sulfur mustard.
Topics: Acute Lung Injury; Animals; Blood Coagulation; Chemical Warfare Agents; Early Growth Response Protein 2; Fibroblast Growth Factor 9; Inflammation; Interleukin-1alpha; Interleukin-6; Male; MicroRNAs; Mustard Gas; Rats; Rats, Sprague-Dawley | 2020 |
Structural Diversity of Zirconium Metal-Organic Frameworks and Effect on Adsorption of Toxic Chemicals.
Topics: Adsorption; Benzene; Environmental Pollutants; Kinetics; Metal-Organic Frameworks; Mustard Gas; Porosity; Zirconium | 2020 |
Glutathione conjugates of the mercapturic acid pathway and guanine adduct as biomarkers of exposure to CEES, a sulfur mustard analog.
Topics: Animals; Cell Line; Chemical Warfare Agents; Chromatography, High Pressure Liquid; Environmental Exposure; Glutathione; Guanine; Humans; Keratinocytes; Mice; Mustard Gas; Skin; Tandem Mass Spectrometry; Toxicity Tests | 2021 |
Immunomodulatory Effect of Curcumin in the Upregulation of Inflammasome Pathway Genes Induced by Sulfur Mustard Analog: An In-vitro Study.
Topics: A549 Cells; Anti-Inflammatory Agents; Caspase 1; Curcumin; Gene Expression Regulation; Humans; Immunologic Factors; Inflammasomes; Interleukin-1beta; Mustard Gas; NF-kappa B p50 Subunit; NLR Proteins; Signal Transduction; Up-Regulation | 2021 |
The effect of
Topics: Acetylcysteine; Angiogenesis Inducing Agents; Animals; Cornea; Doxycycline; Inflammation Mediators; Male; Mustard Gas; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2021 |
Transthyretin as a target of alkylation and a potential biomarker for sulfur mustard poisoning: Electrophoretic and mass spectrometric identification and characterization.
Topics: Alkylation; Biomarkers; Chemical Warfare Agents; Chromatography, Liquid; Electrophoresis; Humans; Mustard Gas; Prealbumin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Time Factors | 2022 |
Evidence for the systemic diffusion of (2-chloroethyl)-ethyl-sulfide, a sulfur mustard analog, and its deleterious effects in brain.
Topics: Administration, Cutaneous; Animals; Brain; Chemical Warfare Agents; DNA Damage; Glutathione; Metabolomics; Mice; Mice, Hairless; Mustard Gas; Skin; Time Factors; Tissue Distribution | 2021 |
Immobilized Regenerable Active Chlorine within a Zirconium-Based MOF Textile Composite to Eliminate Biological and Chemical Threats.
Topics: Animals; Anti-Bacterial Agents; Antiviral Agents; Cell Line; Chemical Warfare Agents; Chlorine; Escherichia coli; Halogenation; Humans; Metal-Organic Frameworks; Microbial Sensitivity Tests; Mustard Gas; Oxidation-Reduction; Protective Clothing; SARS-CoV-2; Staphylococcus aureus; Textiles; Zirconium | 2021 |
Alterations in Mitochondrial and Inflammasome Homeostasis by 2-Chloroethyl Ethyl Sulfide and Their Mitigation by Curcumin: An in Vitro Study.
Topics: Biomarkers; Cell Line; Curcumin; Gene Expression Regulation; Homeostasis; Humans; Inflammasomes; Mitochondria; Mitochondrial Dynamics; Mustard Gas; Signal Transduction | 2021 |
Detoxification of the Toxic Sulfur Mustard Simulant by a Supramolecular Antidote in Vitro and in Vivo.
Topics: Animals; Antidotes; Cell Survival; Density Functional Theory; Eye Diseases; HEK293 Cells; Humans; Macromolecular Substances; Materials Testing; Molecular Structure; Mustard Gas; Rats; Respiratory Tract Diseases; Salts | 2021 |
Is CEES a good analog of sulfur mustard? Macroscopic aspect, histology, and molecular biology comparisons between sulfur mustard and CEES-induced skin lesions.
Topics: Chemical Warfare Agents; Molecular Biology; Mustard Gas; Skin | 2022 |
Sulfur mustard analog 2-chloroethyl ethyl sulfide increases triglycerides by activating DGAT1-dependent biogenesis and inhibiting PGC1ɑ-dependent fat catabolism in immortalized human bronchial epithelial cells.
Topics: Diacylglycerol O-Acyltransferase; Epithelial Cells; Humans; Lipids; Mustard Gas; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; RNA, Messenger; Sulfides | 2023 |
Dual-Function Detoxifying Nanofabrics against Nerve Agent and Blistering Agent Simulants.
Topics: Chemical Warfare Agents; Mustard Gas; Nerve Agents; Sulfides | 2023 |
Bifunctional Fluorescent Probes for the Detection of Mustard Gas and Phosgene.
Topics: Chemical Warfare Agents; Fluorescent Dyes; Humans; Mustard Gas; Phosgene | 2023 |
A fluorescent probe generating
Topics: Chemical Warfare Agents; Fluorescent Dyes; Mustard Gas | 2023 |
HSP90/CDC37 inactivation promotes degradation of LKB1 protein to suppress AMPK signaling in bronchial epithelial cells exposed to sulfur mustard analog, 2-chloroethyl ethyl sulfide.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Cell Cycle Proteins; Chaperonins; Epithelial Cells; HSP90 Heat-Shock Proteins; Humans; Molecular Chaperones; Mustard Gas; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases | 2023 |