2-chloroadenine has been researched along with cladribine in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grippo, P; Hentosh, P | 2 |
| Albertioni, F; Liliemark, J; Lindemalm, S | 1 |
| Bontemps, F; Cardoen, S; Delacauw, A; Van Den Berghe, G; Van Den Neste, E | 1 |
| Ekblom, M; Karlsson, MO; Munafo, A; Novakovic, AM; Savic, RM | 1 |
1 trial(s) available for 2-chloroadenine and cladribine
| Article | Year |
|---|---|
Population Pharmacokinetics of Cladribine in Patients with Multiple Sclerosis.
Topics: Adenine; Administration, Intravenous; Administration, Oral; Adult; Aged; Cladribine; Double-Blind Method; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Models, Biological; Multiple Sclerosis | 2017 |
4 other study(ies) available for 2-chloroadenine and cladribine
| Article | Year |
|---|---|
Template 2-chloro-2'-deoxyadenosine monophosphate inhibits in vitro DNA synthesis.
Topics: Adenine; Bacteriophage M13; Base Sequence; Cladribine; Deoxyribonucleotides; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Humans; Molecular Sequence Data; Templates, Genetic | 1994 |
2-Chloro-2'-deoxyadenosine monophosphate residues in DNA enhance susceptibility to 3'-->5' exonucleases.
Topics: Adenine; Base Sequence; Cladribine; DNA; DNA Nucleotidyltransferases; DNA Polymerase I; DNA Polymerase II; DNA-Directed DNA Polymerase; Escherichia coli; Exodeoxyribonucleases; Molecular Sequence Data; Molecular Weight; Viral Proteins | 1994 |
Stability and analysis of 2-chloro-2'-deoxyadenosine, 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine and 2-chloroadenine in human blood plasma.
Topics: Adenine; Adenine Nucleotides; Aged; Antineoplastic Agents; Arabinonucleosides; Chromatography, High Pressure Liquid; Cladribine; Clofarabine; Female; Humans; Male; Middle Aged; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1997 |
Metabolism and cytotoxic effects of 2-chloroadenine, the major catabolite of 2-chloro-2'-deoxyadenosine.
Topics: Adenine; Antineoplastic Agents; Cladribine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Nucleotides; Tritium; Tumor Cells, Cultured | 2000 |