2-chloro-n(6)cyclopentyladenosine has been researched along with theophylline in 24 studies
| Studies (2-chloro-n(6)cyclopentyladenosine) | Trials (2-chloro-n(6)cyclopentyladenosine) | Recent Studies (post-2010) (2-chloro-n(6)cyclopentyladenosine) | Studies (theophylline) | Trials (theophylline) | Recent Studies (post-2010) (theophylline) |
|---|---|---|---|---|---|
| 252 | 0 | 43 | 20,076 | 1,612 | 1,383 |
| Protein | Taxonomy | 2-chloro-n(6)cyclopentyladenosine (IC50) | theophylline (IC50) |
|---|---|---|---|
| Adenosine receptor A1 | Bos taurus (cattle) | 2.43 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (58.33) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, KA; van Galen, PJ; Williams, M | 1 |
| Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C | 1 |
| Armstrong, S; Downey, JM; Ganote, CE | 2 |
| Baxter, GF; Marber, MS; Patel, VC; Yellon, DM | 1 |
| Florio, C; Rosati, AM; Traversa, U; Vertua, R | 1 |
| Baxter, GF; Kerac, M; Yellon, DM; Zaman, MJ | 1 |
| Daval, JL; Nicolas, F | 1 |
| Edwards, FA; Robertson, SJ | 1 |
| Coney, AM; Marshall, JM | 1 |
| Kaneko, S; Okada, M | 1 |
| Kaneko, S; Kawata, Y; Kondo, T; Mizuno, K; Murakami, T; Okada, M; Wada, K | 1 |
| Jurklies, B; Kaelin-Lang, A; Niemeyer, G | 1 |
| de Jong, JW; de Jonge, R | 1 |
| Song, WJ; Surmeier, DJ; Tkatch, T | 1 |
| Starodub, AM; Wood, JD | 1 |
| Beraudi, A; Di Iorio, P; Notari, S; Poli, A; Traversa, U; Villani, L; Zaccanti, F | 1 |
| Brodmann, M; Lueger, A; Stark, G; Stark, U | 1 |
| Burgdorf, C; Jain, D; Katus, HA; Kurz, T; Richardt, D; Richardt, G; Seyfarth, M | 1 |
| Bradamante, S; de Jong, JW; de Jonge, R; Giacometti, D | 1 |
| de Zeeuw, S; Duncker, DJ; Liem, DA; van den Doel, MA; Verdouw, PD | 1 |
| Alhaj, M; Bozarov, A; Christofi, FL; Cooke, HJ; Grants, I; Hassanain, HH; Ren, T; Wang, YZ; Wunderlich, J; Yu, JG | 1 |
| Fukuda, M; Hino, H; Ishii, E; Kuzume, K; Morimoto, T; Suzuki, Y | 1 |
| Clasadonte, J; Halassa, MM; Haydon, PG; McIver, SR; Schmitt, LI | 1 |
1 review(s) available for 2-chloro-n(6)cyclopentyladenosine and theophylline
| Article | Year |
|---|---|
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship | 1992 |
23 other study(ies) available for 2-chloro-n(6)cyclopentyladenosine and theophylline
| Article | Year |
|---|---|
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines | 1998 |
Preconditioning of isolated rabbit cardiomyocytes: induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor.
Topics: Adenosine; Animals; Cell Size; Cell Survival; Cells, Cultured; Glucose; Heart; Myocardial Ischemia; Myocardium; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rabbits; Theophylline; Time Factors | 1994 |
Adenosine receptor involvement in a delayed phase of myocardial protection 24 hours after ischemic preconditioning.
Topics: Adenosine; Animals; Heart; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Rabbits; Receptors, Purinergic P1; Theophylline; Time Factors | 1994 |
Adenosine and A1 selective agonists offer minimal protection against ischaemic injury to isolated rat cardiomyocytes.
Topics: Adenosine; Animals; Carbachol; Cell Death; Cells, Cultured; Iodoacetates; Iodoacetic Acid; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Rats; Rats, Sprague-Dawley; Theophylline | 1993 |
Inhibitory and excitatory effects of adenosine antagonists on spontaneous locomotor activity in mice.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Male; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purines; Sulfonamides; Theophylline; Xanthines | 1997 |
Protection against global ischemia in the rabbit isolated heart 24 hours after transient adenosine A1 receptor activation.
Topics: Adenosine; Animals; Blood Pressure; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline | 1997 |
Non-selective effects of adenosine A1 receptor ligands on energy metabolism and macromolecular biosynthesis in cultured central neurons.
Topics: Adenosine; Adenylyl Cyclases; Animals; Biological Transport; Cell Survival; Cells, Cultured; Cyclic AMP; Deoxyglucose; Embryo, Mammalian; Energy Metabolism; Female; Kinetics; Leucine; Ligands; Neurons; Prosencephalon; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA; Theophylline; Uridine | 1998 |
ATP and glutamate are released from separate neurones in the rat medial habenula nucleus: frequency dependence and adenosine-mediated inhibition of release.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine Triphosphate; Aniline Compounds; Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Habenula; Male; Neurons; Nucleotidases; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Glutamate; Receptors, Purinergic P1; Suramin; Synaptic Transmission; Synaptic Vesicles; Theophylline | 1998 |
Role of adenosine and its receptors in the vasodilatation induced in the cerebral cortex of the rat by systemic hypoxia.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood-Brain Barrier; Erythrocytes; Hypoxia; Laser-Doppler Flowmetry; Male; Parietal Lobe; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilation | 1998 |
Pharmacological interactions between magnesium ion and adenosine on monoaminergic system in the central nervous system.
Topics: Adenosine; Animals; Biogenic Monoamines; Caffeine; Carbamazepine; Central Nervous System; Central Nervous System Stimulants; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hippocampus; Magnesium; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Serotonin; Theobromine; Theophylline; Visual Cortex | 1998 |
Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin.
Topics: Adenosine; Animals; Antihypertensive Agents; Biological Transport; Caffeine; Central Nervous System Stimulants; Fluoxetine; Hippocampus; Male; Microdialysis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quipazine; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Theobromine; Theophylline; Vasodilator Agents | 1999 |
Effects of adenosinergic agents on the vascular resistance and on the optic nerve response in the perfused cat eye.
Topics: Adenosine; Animals; Cats; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Electrophysiology; Female; Optic Nerve; Perfusion; Phenethylamines; Photic Stimulation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Retina; Theobromine; Theophylline; Vascular Resistance | 1999 |
Ischemic preconditioning and glucose metabolism during low-flow ischemia: role of the adenosine A1 receptor.
Topics: Adenosine; Animals; Glucose; Glycolysis; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Myocardium; Perfusion; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Regional Blood Flow; Theophylline | 1999 |
Adenosine receptor expression and modulation of Ca(2+) channels in rat striatal cholinergic interneurons.
Topics: Adenosine; Animals; Calcium Channels, N-Type; Choline O-Acetyltransferase; Corpus Striatum; Ethylmaleimide; GTP-Binding Proteins; Guanosine Diphosphate; In Vitro Techniques; Interneurons; Membrane Potentials; Patch-Clamp Techniques; Phenethylamines; Rats; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theophylline; Thionucleotides | 2000 |
Histamine H(2) receptor activated chloride conductance in myenteric neurons from guinea pig small intestine.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine; Animals; Calcium Channel Blockers; Chlorides; Cyclic AMP; Cyclooxygenase Inhibitors; Electric Conductivity; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Guinea Pigs; Histamine; Intestine, Small; Membrane Potentials; Myenteric Plexus; Neurons; Niflumic Acid; omega-Conotoxins; Paracrine Communication; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Receptors, Histamine H2; Stress, Psychological; Theophylline; Thionucleotides | 2000 |
The calcium-dependent [3H]acetylcholine release from synaptosomes of brown trout (Salmo trutta) optic tectum is inhibited by adenosine A1 receptors: effects of enucleation on A1 receptor density and cholinergic markers.
Topics: Acetylcholine; Acetylcholinesterase; Adenosine; Afferent Pathways; Animals; Calcium; Calcium Channel Blockers; Choline O-Acetyltransferase; Kinetics; Membrane Potentials; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Potassium Chloride; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Superior Colliculi; Synaptosomes; Theophylline; Tritium; Trout | 2001 |
Antiarrhythmic effects of adenosine on ischemia-induced ventricular fibrillation.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Ischemia; Purinergic P1 Receptor Agonists; Theophylline; Ventricular Fibrillation | 2001 |
Adenosine inhibits norepinephrine release in the postischemic rat heart: the mechanism of neuronal stunning.
Topics: Adenosine; Analysis of Variance; Animals; Brimonidine Tartrate; Electric Stimulation; Enzyme Inhibitors; Male; Myocardial Stunning; Myocardium; Norepinephrine; Perfusion; Phenethylamines; Phenylisopropyladenosine; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Quinoxalines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Sympathetic Nervous System; Theophylline; Time Factors; Xanthines | 2001 |
Role of adenosine and glycogen in ischemic preconditioning of rat hearts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Glycogen; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Male; Myocardium; Phosphates; Phosphocreatine; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 2001 |
Role of adenosine in ischemic preconditioning in rats depends critically on the duration of the stimulus and involves both A(1) and A(3) receptors.
Topics: Acetamides; Adenosine; Analysis of Variance; Animals; Cryoprotective Agents; Dihydropyridines; Histamine H1 Antagonists; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Pyrilamine; Rats; Rats, Wistar; Receptors, Purinergic; Receptors, Purinergic P1; Theophylline; Time Factors | 2001 |
Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine.
Topics: Adenosine; Animals; Chlorides; Cimetidine; Colon; Dihydropyridines; Dimaprit; Dose-Response Relationship, Drug; Enteric Nervous System; Gastrointestinal Motility; Guinea Pigs; Histamine; Histamine Agonists; Histamine H2 Antagonists; In Vitro Techniques; Intestinal Secretions; Male; Mecamylamine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neural Inhibition; Neurogenic Bowel; Neurokinin-1 Receptor Antagonists; Nicotinic Antagonists; Piperidines; Propane; Receptor, Adenosine A1; Receptor, Adenosine A3; Receptors, Histamine H2; Receptors, Neurokinin-1; Reflex; Theophylline; Xanthines | 2009 |
Adenosine A1 receptor blockage mediates theophylline-associated seizures.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Kinase; Animals; Behavior, Animal; Body Temperature; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Enzyme Inhibitors; Hyperthermia, Induced; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Lew; Seizures; Theophylline; Tubercidin | 2010 |
Chronic sleep restriction disrupts sleep homeostasis and behavioral sensitivity to alcohol by reducing the extracellular accumulation of adenosine.
Topics: Action Potentials; Adenosine; Alcohols; Animals; Brain Waves; Electroencephalography; Excitatory Postsynaptic Potentials; Extracellular Fluid; Hippocampus; Homeostasis; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Movement Disorders; Neurons; Purinergic P1 Receptor Antagonists; Sleep Deprivation; Sleep Stages; Theophylline; Thioinosine; Time Factors; Wakefulness | 2014 |