2-chloro-n(6)cyclopentyladenosine has been researched along with phenylisopropyladenosine in 7 studies
| Studies (2-chloro-n(6)cyclopentyladenosine) | Trials (2-chloro-n(6)cyclopentyladenosine) | Recent Studies (post-2010) (2-chloro-n(6)cyclopentyladenosine) | Studies (phenylisopropyladenosine) | Trials (phenylisopropyladenosine) | Recent Studies (post-2010) (phenylisopropyladenosine) |
|---|---|---|---|---|---|
| 252 | 0 | 43 | 63 | 0 | 10 |
| Protein | Taxonomy | 2-chloro-n(6)cyclopentyladenosine (IC50) | phenylisopropyladenosine (IC50) |
|---|---|---|---|
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | 1.8613 | |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | 0.0294 | |
| Adenosine receptor A3 | Rattus norvegicus (Norway rat) | 0.0497 | |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | 0.2898 | |
| Adenosine receptor A1 | Homo sapiens (human) | 0.83 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.2898 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, KA; van Galen, PJ; Williams, M | 1 |
| Daly, JW; Olsson, RA; Secunda, S; Thompson, RD | 1 |
| Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C | 1 |
| Cappellacci, L; Franchetti, P; Grifantini, M; Lucacchini, A; Marchetti, S; Martini, C; Mazzoni, MR; Trincavelli, L | 1 |
| Barbhaiya, H; IJzerman, AP; Rivkees, SA | 1 |
| Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T | 1 |
| Barak, D; Biadatti, T; Chen, W; Gao, ZG; Jacobson, KA; Johnson, CR; Kim, SG; Kim, SK; Lee, K | 1 |
1 review(s) available for 2-chloro-n(6)cyclopentyladenosine and phenylisopropyladenosine
| Article | Year |
|---|---|
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship | 1992 |
6 other study(ies) available for 2-chloro-n(6)cyclopentyladenosine and phenylisopropyladenosine
| Article | Year |
|---|---|
Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors.
Topics: 2-Chloroadenosine; Animals; Brain; In Vitro Techniques; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1991 |
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines | 1998 |
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Brain; Cattle; Enzyme Inhibitors; In Vitro Techniques; Male; Membranes; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Testis | 1998 |
Identification of the adenine binding site of the human A1 adenosine receptor.
Topics: Adenine; Amides; Amino Acid Sequence; Amino Acids; Binding Sites; DNA, Complementary; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1 | 1999 |
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines | 1999 |
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.
Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Epoxy Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Models, Molecular; Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Ribose; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2002 |