Compounds > 2-chloro-n(6)cyclopentyladenosine

Page last updated: 2024-09-03

2-chloro-n(6)cyclopentyladenosine and n-(1-methyl-2-phenylethyl)adenosine, (s)-isomer

2-chloro-n(6)cyclopentyladenosine has been researched along with n-(1-methyl-2-phenylethyl)adenosine, (s)-isomer in 5 studies

Compound Research Comparison

Studies (2-chloro-n(6)cyclopentyladenosine)	Trials (2-chloro-n(6)cyclopentyladenosine)	Recent Studies (post-2010) (2-chloro-n(6)cyclopentyladenosine)	Studies (n-(1-methyl-2-phenylethyl)adenosine, (s)-isomer)	Trials (n-(1-methyl-2-phenylethyl)adenosine, (s)-isomer)	Recent Studies (post-2010) (n-(1-methyl-2-phenylethyl)adenosine, (s)-isomer)
252	0	43	20	0	2

Protein Interaction Comparison

Protein	Taxonomy	2-chloro-n(6)cyclopentyladenosine (IC50)	n-(1-methyl-2-phenylethyl)adenosine, (s)-isomer (IC50)
Adenosine receptor A1	Rattus norvegicus (Norway rat)		0.105

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (80.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Daly, JW; Olsson, RA; Secunda, S; Thompson, RD	1
Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C	1
Cappellacci, L; Franchetti, P; Grifantini, M; Lucacchini, A; Marchetti, S; Martini, C; Mazzoni, MR; Trincavelli, L	1
Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T	1
Barak, D; Biadatti, T; Chen, W; Gao, ZG; Jacobson, KA; Johnson, CR; Kim, SG; Kim, SK; Lee, K	1

Other Studies

5 other study(ies) available for 2-chloro-n(6)cyclopentyladenosine and n-(1-methyl-2-phenylethyl)adenosine, (s)-isomer

Article	Year
Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors. Journal of medicinal chemistry, 1991, Volume: 34, Issue:12 Topics: 2-Chloroadenosine; Animals; Brain; In Vitro Techniques; Rats; Receptors, Purinergic; Structure-Activity Relationship	1991
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines	1998
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. Journal of medicinal chemistry, 1998, May-07, Volume: 41, Issue:10 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Brain; Cattle; Enzyme Inhibitors; In Vitro Techniques; Male; Membranes; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Testis	1998
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells. Molecular pharmacology, 1999, Volume: 56, Issue:4 Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines	1999
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary. Journal of medicinal chemistry, 2002, Sep-26, Volume: 45, Issue:20 Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Epoxy Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Models, Molecular; Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Ribose; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship	2002