2-chloro-n(6)cyclopentyladenosine and adenosine-5'-(n-ethylcarboxamide)

2-chloro-n(6)cyclopentyladenosine has been researched along with adenosine-5'-(n-ethylcarboxamide) in 40 studies

Compound Research Comparison

Studies (2-chloro-n(6)cyclopentyladenosine)	Trials (2-chloro-n(6)cyclopentyladenosine)	Recent Studies (post-2010) (2-chloro-n(6)cyclopentyladenosine)	Studies (adenosine-5'-(n-ethylcarboxamide))	Trials (adenosine-5'-(n-ethylcarboxamide))	Recent Studies (post-2010) (adenosine-5'-(n-ethylcarboxamide))
252	0	43	1,333	4	133

Protein Interaction Comparison

Protein	Taxonomy	adenosine-5'-(n-ethylcarboxamide) (IC50)
Adenosine receptor A3	Homo sapiens (human)	0.0097
Alpha-2B adrenergic receptor	Rattus norvegicus (Norway rat)	0.037
Alpha-2C adrenergic receptor	Rattus norvegicus (Norway rat)	0.037
Alpha-2A adrenergic receptor	Rattus norvegicus (Norway rat)	0.037
Adenosine receptor A1	Rattus norvegicus (Norway rat)	0.4498
Adenosine receptor A2a	Homo sapiens (human)	0.0336
Adenosine receptor A2b	Rattus norvegicus (Norway rat)	0.0175
Adenosine receptor A1	Homo sapiens (human)	0.0007
Adenosine receptor A2a	Rattus norvegicus (Norway rat)	0.0513
Adenosine receptor A1	Gallus gallus (chicken)	0.017

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	23 (57.50)	18.2507
2000's	11 (27.50)	29.6817
2010's	5 (12.50)	24.3611
2020's	1 (2.50)	2.80

Authors

Authors	Studies
Jacobson, KA; van Galen, PJ; Williams, M	1
Conti, A; Ongini, E; Pocar, D; Seminati, M; Viziano, M; Zocchi, C	1
Borea, PA; Camaioni, E; Conti, A; Cristalli, G; Dionisotti, S; Monopoli, A; Ongini, E; Vittori, S; Volpini, R	1
Camaioni, E; Conti, A; Cristalli, G; Dionisotti, S; Monopoli, A; Ongini, E; Vittori, S; Volpini, R; Zocchi, C	1
Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C	1
Cappellacci, L; Franchetti, P; Grifantini, M; Lucacchini, A; Marchetti, S; Martini, C; Mazzoni, MR; Trincavelli, L	1
Barbhaiya, H; IJzerman, AP; Rivkees, SA	1
Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T	1
Albinson, FD; Ayres, BE; Butchers, PR; Chambers, CL; Cherry, PC; Ellis, F; Ewan, GB; Gregson, M; Keeling, SE; Knight, J; Mills, K; Ravenscroft, P; Reynolds, LH; Sanjar, S; Sheehan, MJ	1
Jacobson, KA; Ji, X; Li, AH; Marquez, VE; Melman, N; Ravi, RG; Shin, KJ; Siddiqui, MA	1
de Groote, M; IJzerman, AP; Lorenzen, A; Stannek, C; van der Klein, PA; van Tilburg, EW; von Frijtag Drabbe Künzel, J	1
Barak, D; Biadatti, T; Chen, W; Gao, ZG; Jacobson, KA; Johnson, CR; Kim, SG; Kim, SK; Lee, K	1
Beukers, MW; IJzerman, AP; Klaasse, EC; Koomen, GJ; Von Frijtag Drabbe Künzel, JK; Wanner, MJ	1
Deflorian, F; Gao, ZG; Jacobson, KA; Jiang, X; Moss, SM; Paoletta, S; Phan, K; Tosh, DK	1
Dowell, SJ; Frattini, E; Frenguelli, BG; Hemmings, JL; Knight, A; Ladds, G; Leuenberger, M; Lochner, M; Winfield, I	1
Ahn, S; Cheong, JH; Jacobson, KA; Jeong, LS; Jin, SH; Kim, G; Kim, HJ; Kim, J; Lee, E; Lee, M; Noh, M; Yu, J	1
Auchampach, JA; Bitant, A; Ciancetta, A; Cui, Z; Gao, ZG; Gavrilova, O; Jacobson, KA; Lieberman, DI; Liu, N; Mannes, P; Mattison, JA; Rao, H; Reitman, ML; Rothwell, AC; Salmaso, V; Tosh, DK; Vaughan, KL	1
Angeli, A; Ben, DD; Buccioni, M; Catarzi, D; Ceni, C; Colotta, V; Gratteri, P; Marucci, G; Nocentini, A; Supuran, CT; Varano, F; Volpini, R	1
Lucchi, R; Poli, A; Rosati, AM; Traversa, U	1
Bonizzoni, E; Casati, C; Milani, S; Monopoli, A; Ongini, E	1
Schiele, JO; Schwabe, U	1
Christofi, FL; Wood, JD	1
Chintala, M; Chiu, PJ; Dionisotti, S; Ongini, E; Sandoli, D	1
Conti, A; Dionisotti, S; Gatta, F; Ongini, E; Sandoli, D; Zocchi, C	1
Bonizzoni, E; Casati, C; Dionisotti, S; Monopoli, A; Ongini, E; Zocchi, C	1
Bottrill, FE; Hiley, CR; Richardson, PJ; Warnock, J	1
Adami, M; Bertorelli, R; Ferri, N; Foddi, MC; Ongini, E	1
Busca, G; Castoldi, G; Genovesi, S; Golin, R; Panzacchi, G; Protasoni, G; Stella, A	1
De Sarro, A; De Sarro, G; Donato Di Paola, E; Falconi, U; Ferreri, G	1
Florio, C; Rosati, AM; Traversa, U; Vertua, R	1
Casati, C; Forlani, A; Lozza, G; Monopoli, A	1
Busca, G; Demarchi, B; Golin, R; Panzacchi, G; Protasoni, G; Stella, A	1
Cutler, BS; Dobson, JG; Fenton, RA; Li, Jm; Peyton, BD; Powell, CC; Wheeler, HB	1
Camisasca, P; Genovesi, S; Golin, R; Pieruzzi, F; Protasoni, G; Ragonesi, G; Stella, A; Zanchetti, A	1
Doering, A; Middlekauff, HR; Weiss, JN	1
Belem, PC; Chen, JF; Cronstein, B; Elson, G; Fink, JS; Jacobson, M; Leibovich, SJ; Montesinos, C; Pinhal-Enfield, G; Ramanathan, M; Rosania, A; Schwarzschild, MA	1
Aqvist, J; Centeno, NB; Gutiérrez-de-Terán, H; Pastor, M; Sanz, F	1
Mustafa, SJ; Oldenburg, PJ; Schnermann, J; Tawfik, HE	1
Cao, Y; Xie, KQ; Zhu, XZ	1
Mustafa, SJ; Nadeem, A; Ponnoth, DS; Tilley, S	1

Reviews

1 review(s) available for 2-chloro-n(6)cyclopentyladenosine and adenosine-5'-(n-ethylcarboxamide)

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992

Other Studies

39 other study(ies) available for 2-chloro-n(6)cyclopentyladenosine and adenosine-5'-(n-ethylcarboxamide)

Article	Year
2-[N'-(3-arylallylidene)hydrazino]adenosines showing A2a adenosine agonist properties and vasodilation activity. Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18 Topics: Adenosine; Animals; Aorta; Hydrazines; In Vitro Techniques; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Structure-Activity Relationship; Vasodilator Agents	1995
2-Aralkynyl and 2-heteroalkynyl derivatives of adenosine-5'-N-ethyluronamide as selective A2a adenosine receptor agonists. Journal of medicinal chemistry, 1995, Apr-28, Volume: 38, Issue:9 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Male; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1	1995
2-Alkynyl derivatives of adenosine-5'-N-ethyluronamide: selective A2 adenosine receptor agonists with potent inhibitory activity on platelet aggregation. Journal of medicinal chemistry, 1994, May-27, Volume: 37, Issue:11 Topics: Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Chemical Phenomena; Chemistry, Physical; Heart Rate; Hydroxylation; Male; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Structure-Activity Relationship; Vasodilation	1994
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines	1998
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. Journal of medicinal chemistry, 1998, May-07, Volume: 41, Issue:10 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Brain; Cattle; Enzyme Inhibitors; In Vitro Techniques; Male; Membranes; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Testis	1998
Identification of the adenine binding site of the human A1 adenosine receptor. The Journal of biological chemistry, 1999, Feb-05, Volume: 274, Issue:6 Topics: Adenine; Amides; Amino Acid Sequence; Amino Acids; Binding Sites; DNA, Complementary; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1	1999
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells. Molecular pharmacology, 1999, Volume: 56, Issue:4 Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines	1999
The discovery and synthesis of highly potent, A2a receptor agonists. Bioorganic & medicinal chemistry letters, 2000, Feb-21, Volume: 10, Issue:4 Topics: Adenosine; Anti-Inflammatory Agents; GTP-Binding Proteins; Purinergic P1 Receptor Agonists; Solubility; Structure-Activity Relationship	2000
Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Animals; Cell Membrane; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Purine Nucleosides; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Sulfur Radioisotopes	2000
5'-O-alkyl ethers of N,2-substituted adenosine derivatives: partial agonists for the adenosine A1 and A3 receptors. Journal of medicinal chemistry, 2001, Aug-30, Volume: 44, Issue:18 Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cerebral Cortex; Cricetinae; Cyclic AMP; Humans; In Vitro Techniques; Purinergic P1 Receptor Agonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Structure-Activity Relationship	2001
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary. Journal of medicinal chemistry, 2002, Sep-26, Volume: 45, Issue:20 Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Epoxy Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Models, Molecular; Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Ribose; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship	2002
N6-cyclopentyl-2-(3-phenylaminocarbonyltriazene-1-yl)adenosine (TCPA), a very selective agonist with high affinity for the human adenosine A1 receptor. Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8 Topics: Adenosine; Animals; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Agonists; Radioligand Assay; Structure-Activity Relationship; Triazenes	2003
Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. Journal of medicinal chemistry, 2012, Sep-27, Volume: 55, Issue:18 Topics: Animals; Anticonvulsants; CHO Cells; Cricetinae; Cricetulus; Humans; Male; Mice; Molecular Docking Simulation; Nucleosides; Protein Conformation; Receptor, Adenosine A1; Structure-Activity Relationship	2012
Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity. Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3 Topics: Adenosine; Bridged Bicyclo Compounds, Heterocyclic; Cyclopentanes; Dose-Response Relationship, Drug; Drug Discovery; Humans; Molecular Structure; Purinergic P1 Receptor Agonists; Receptor, Adenosine A1; Receptor, Adenosine A3; Structure-Activity Relationship; Substrate Specificity	2016
Polypharmacology of N Journal of medicinal chemistry, 2017, 09-14, Volume: 60, Issue:17 Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adiponectin; Animals; Cell Line; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Male; Mice; Mice, Inbred C57BL; Polypharmacology; PPAR delta; PPAR gamma; Receptor, Adenosine A3	2017
Design and in Vivo Characterization of A Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3 Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Bridged Bicyclo Compounds; CHO Cells; Cricetulus; Drug Design; HEK293 Cells; Humans; Macaca fascicularis; Male; Mice, Inbred C57BL; Molecular Docking Simulation; Molecular Structure; Receptor, Adenosine A1; Structure-Activity Relationship	2019
Discovery of first-in-class multi-target adenosine A European journal of medicinal chemistry, 2020, Sep-01, Volume: 201 Topics: Adenosine A2 Receptor Antagonists; Animals; Antigens, Neoplasm; Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Catalytic Domain; CHO Cells; Cricetulus; Enzyme Assays; Humans; Molecular Docking Simulation; Molecular Structure; Protein Binding; Pyrazines; Receptor, Adenosine A2A; Structure-Activity Relationship; Triazoles	2020
Biochemical and pharmacological evidence for the presence of A1 but not A2a adenosine receptors in the brain of the low vertebrate teleost Carassius auratus (goldfish). Neurochemistry international, 1995, Volume: 26, Issue:4 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Goldfish; Hydrogen-Ion Concentration; Mammals; Neurotransmitter Agents; Phenethylamines; Radioligand Assay; Receptors, Purinergic P1; Species Specificity; Temperature	1995
Modeling hemodynamic profiles by telemetry in the rat. A study with A1 and A2a adenosine agonists. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:4 Pt 1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-Agonists; Animals; Hemodynamics; Male; Models, Biological; Platelet Aggregation Inhibitors; Rats; Rats, Inbred SHR; Telemetry	1995
Characterization of the adenosine receptor in microvascular coronary endothelial cells. European journal of pharmacology, 1994, Sep-15, Volume: 269, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Antihypertensive Agents; Cells, Cultured; Colforsin; Coronary Vessels; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Isoproterenol; Myocardium; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Thioinosine; Vasodilator Agents	1994
Electrophysiological subtypes of inhibitory P1 purinoceptors on myenteric neurones of guinea-pig small bowel. British journal of pharmacology, 1994, Volume: 113, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Membrane Potentials; Myenteric Plexus; Phenethylamines; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1	1994
In vivo and ex vivo effects of adenosine A1 and A2 receptor agonists on platelet aggregation in the rabbit. European journal of pharmacology, 1994, Jun-23, Volume: 259, Issue:1 Topics: Adenosine; Adenosine Diphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rabbits	1994
Effects of the new A2 adenosine receptor antagonist 8FB-PTP, an 8 substituted pyrazolo-triazolo-pyrimidine, on in vitro functional models. British journal of pharmacology, 1994, Volume: 112, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phosphoric Diester Hydrolases; Platelet Aggregation; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Rabbits; Rats; Rats, Sprague-Dawley; Triazoles; Vasodilator Agents; Xanthines	1994
Repeated administration of selective adenosine A1 and A2 receptor agonists in the spontaneously hypertensive rat: tolerance develops to A1-mediated hemodynamic effects. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Drug Tolerance; Hemodynamics; Male; Phenethylamines; Rats; Rats, Inbred SHR; Receptors, Purinergic P1	1994
Effects of pH on responses to adenosine, CGS 21680, carbachol and nitroprusside in the isolated perfused superior mesenteric arterial bed of the rat. British journal of pharmacology, 1995, Volume: 116, Issue:6 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Carbachol; Colforsin; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Nitroprusside; Perfusion; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents; Xanthines	1995
Effects of repeated administration of selective adenosine A1 and A2A receptor agonists on pentylenetetrazole-induced convulsions in the rat. European journal of pharmacology, 1995, Dec-29, Volume: 294, Issue:2-3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Dose-Response Relationship, Drug; Male; Pentylenetetrazole; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Seizures	1995
Effects of adenosine-receptor agonists on renin release in anaesthetized rats. Journal of hypertension, 1995, Volume: 13, Issue:12 Pt 2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Hemodynamics; Infusions, Intravenous; Kidney; Nerve Fibers; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Renin	1995
Repeated treatment with adenosine A1 receptor agonist and antagonist modifies the anticonvulsant properties of CPPene. European journal of pharmacology, 1996, Dec-19, Volume: 317, Issue:2-3 Topics: Acoustic Stimulation; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Mice; Mice, Inbred DBA; Piperazines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Triazoles; Xanthines	1996
Inhibitory and excitatory effects of adenosine antagonists on spontaneous locomotor activity in mice. Life sciences, 1997, Volume: 60, Issue:17 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antineoplastic Agents; Male; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purines; Sulfonamides; Theophylline; Xanthines	1997
Hemodynamic changes do not mediate the cardioprotection induced by the A1, adenosine receptor agonist CCPA in the rabbit. Pharmacological research, 1997, Volume: 35, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Felodipine; Hemodynamics; Male; Myocardial Infarction; Purinergic P1 Receptor Agonists; Rabbits; Vasodilator Agents	1997
Effects of adenosine receptor agonists on renal function in anaesthetized rats. Journal of hypertension, 1997, Volume: 15, Issue:12 Pt 2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Denervation; Glomerular Filtration Rate; Hypertension, Renal; Kidney; Male; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Purinergic P1; Receptors, Purinergic P2; Sodium; Urodynamics	1997
Adenosine A2a receptors increase arterial endothelial cell nitric oxide. The Journal of surgical research, 1998, Volume: 80, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carotid Arteries; Cells, Cultured; Endothelium, Vascular; Humans; Iliac Artery; Nitric Oxide; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Xanthines	1998
Effects of adenosine receptor agonists on efferent renal nerve activity in anesthetized rats. Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Baroreflex; Blood Pressure; Denervation; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Kidney; Male; Neurons, Efferent; Nitroprusside; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Regression Analysis; Sympathetic Nervous System; Time Factors; Vagotomy	2000
Adenosine enhances neuroexcitability by inhibiting a slow postspike afterhyperpolarization in rabbit vagal afferent neurons. Circulation, 2001, Mar-06, Volume: 103, Issue:9 Topics: Action Potentials; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cadmium; Colforsin; Neurons, Afferent; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Time Factors; Vagus Nerve; Xanthines	2001
Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin. The American journal of pathology, 2002, Volume: 160, Issue:6 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Cells, Cultured; Drosophila Proteins; Endothelial Growth Factors; Female; Interferon-gamma; Lipopolysaccharides; Lymphokines; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenethylamines; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theobromine; Toll-Like Receptor 4; Toll-Like Receptors; Triazines; Triazoles; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xanthines	2002
Comparative analysis of putative agonist-binding modes in the human A1 adenosine receptor. Chembiochem : a European journal of chemical biology, 2004, Jun-07, Volume: 5, Issue:6 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine-5'-(N-ethylcarboxamide); Binding Sites; Humans; Mathematics; Models, Molecular; Receptor, Adenosine A1; Thermodynamics	2004
Role of A1 adenosine receptors in regulation of vascular tone. American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:3 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Female; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Receptor, Adenosine A1; Type C Phospholipases; Vasodilation; Vasodilator Agents; Xanthines	2005
Role of the second transmembrane domain of rat adenosine A1 receptor in ligand-receptor interaction. Biochemical pharmacology, 2006, Mar-14, Volume: 71, Issue:6 Topics: Adenine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Structure, Tertiary; Rats; Receptor, Adenosine A1; Xanthines	2006
Involvement of A1 adenosine receptors in altered vascular responses and inflammation in an allergic mouse model of asthma. American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Administration, Inhalation; Aerosols; Ambrosia; Animals; Antigens, Plant; Aorta; Asthma; Blotting, Western; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-5; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Plethysmography, Whole Body; Polymerase Chain Reaction; Receptor, Adenosine A1; RNA, Messenger; Vasodilation	2010