2-chloro-n(6)cyclopentyladenosine has been researched along with 2-chloroadenosine in 10 studies
| Studies (2-chloro-n(6)cyclopentyladenosine) | Trials (2-chloro-n(6)cyclopentyladenosine) | Recent Studies (post-2010) (2-chloro-n(6)cyclopentyladenosine) | Studies (2-chloroadenosine) | Trials (2-chloroadenosine) | Recent Studies (post-2010) (2-chloroadenosine) |
|---|---|---|---|---|---|
| 252 | 0 | 43 | 889 | 13 | 47 |
| Protein | Taxonomy | 2-chloro-n(6)cyclopentyladenosine (IC50) | 2-chloroadenosine (IC50) |
|---|---|---|---|
| high affinity choline transporter 1 isoform a | Homo sapiens (human) | 0.5377 | |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | 0.037 | |
| Adenosine receptor A2b | Rattus norvegicus (Norway rat) | 0.16 | |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | 0.16 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (80.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, KA; van Galen, PJ; Williams, M | 1 |
| Daly, JW; Olsson, RA; Secunda, S; Thompson, RD | 1 |
| Jacobson, KA; Ji, XD; Kim, HO; Olah, ME; Siddiqi, SM; Stiles, GL | 1 |
| Cappellacci, L; Franchetti, P; Grifantini, M; Lucacchini, A; Marchetti, S; Martini, C; Mazzoni, MR; Trincavelli, L | 1 |
| Barbieri, D; Camaioni, E; Costanzi, S; Cristalli, G; Franceschi, C; Vittori, S; Volpini, R | 1 |
| Barbhaiya, H; IJzerman, AP; Rivkees, SA | 1 |
| Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T | 1 |
| Barak, D; Biadatti, T; Chen, W; Gao, ZG; Jacobson, KA; Johnson, CR; Kim, SG; Kim, SK; Lee, K | 1 |
| Bellingham, MC; Berger, AJ | 1 |
| Clark, RS; Dixon, CE; Griffith, RP; Jackson, EK; Jenkins, LW; Kochanek, PM; Melick, JA; Peters, GW; Vagni, VA; Varma, MR | 1 |
1 review(s) available for 2-chloro-n(6)cyclopentyladenosine and 2-chloroadenosine
| Article | Year |
|---|---|
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship | 1992 |
9 other study(ies) available for 2-chloro-n(6)cyclopentyladenosine and 2-chloroadenosine
| Article | Year |
|---|---|
Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors.
Topics: 2-Chloroadenosine; Animals; Brain; In Vitro Techniques; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1991 |
2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Cell Membrane; CHO Cells; Cricetinae; Molecular Structure; Rats; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship | 1994 |
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Brain; Cattle; Enzyme Inhibitors; In Vitro Techniques; Male; Membranes; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Testis | 1998 |
Modulation of apoptosis in human lymphocytes by adenosine analogues.
Topics: 2-Chloroadenosine; Apoptosis; Cells, Cultured; Deoxyadenosines; Flow Cytometry; Humans; Lymphocytes; Models, Chemical; Propidium; Structure-Activity Relationship | 1998 |
Identification of the adenine binding site of the human A1 adenosine receptor.
Topics: Adenine; Amides; Amino Acid Sequence; Amino Acids; Binding Sites; DNA, Complementary; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1 | 1999 |
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines | 1999 |
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.
Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Epoxy Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Models, Molecular; Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Ribose; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2002 |
Adenosine suppresses excitatory glutamatergic inputs to rat hypoglossal motoneurons in vitro.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Female; Hypoglossal Nerve; Kynurenic Acid; Male; Membrane Potentials; Motor Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Purinergic P1; Xanthines | 1994 |
Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain Injuries; Cell Count; Cerebral Cortex; Hand Strength; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Postural Balance; Psychomotor Performance; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Xanthines | 2002 |