2-chloro-n(6)cyclopentyladenosine and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine

2-chloro-n(6)cyclopentyladenosine has been researched along with 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine in 51 studies

Compound Research Comparison

Studies (2-chloro-n(6)cyclopentyladenosine)	Trials (2-chloro-n(6)cyclopentyladenosine)	Recent Studies (post-2010) (2-chloro-n(6)cyclopentyladenosine)	Studies (2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine)	Trials (2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine)	Recent Studies (post-2010) (2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine)
252	0	43	952	2	169

Protein Interaction Comparison

Protein	Taxonomy	2-chloro-n(6)cyclopentyladenosine (IC50)	2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine (IC50)
Adenosine receptor A2a	Homo sapiens (human)		0.019

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	33 (64.71)	18.2507
2000's	14 (27.45)	29.6817
2010's	4 (7.84)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jacobson, KA; van Galen, PJ; Williams, M	1
Conti, A; Ongini, E; Pocar, D; Seminati, M; Viziano, M; Zocchi, C	1
Borea, PA; Camaioni, E; Conti, A; Cristalli, G; Dionisotti, S; Monopoli, A; Ongini, E; Vittori, S; Volpini, R	1
Jacobson, KA; Ji, XD; Kim, HO; Olah, ME; Siddiqi, SM; Stiles, GL	1
Fredholm, BB; Hegler, J; Hessling, J; Klotz, KN; Kull, B; Lohse, MJ; Owman, C	1
Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T	1
Batra, VK; Borron, P; Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN	1
Gao, ZG; Jacobson, KA	1
Dowell, SJ; Frattini, E; Frenguelli, BG; Hemmings, JL; Knight, A; Ladds, G; Leuenberger, M; Lochner, M; Winfield, I	1
Ahn, S; Cheong, JH; Jacobson, KA; Jeong, LS; Jin, SH; Kim, G; Kim, HJ; Kim, J; Lee, E; Lee, M; Noh, M; Yu, J	1
Klotz, KN; Lehr, HA; Lorenzen, A; Messmer, K; Nolte, D; Zimmer, FJ	1
Downey, JM; Liu, GS; Olsson, RA; Thornton, JD	1
Amoroso, S; Annunziato, L; Di Renzo, G; Iannotti, E; Saggese, ML	1
Lucchi, R; Poli, A; Rosati, AM; Traversa, U	1
Barbhaiya, H; Lasbury, ME; Rivkees, SA	1
Lasley, RD; Mentzer, RM; Noble, MA; Paulsen, KL	1
Schiele, JO; Schwabe, U	1
Borchard, U; Felsch, A; Stöcker, K	1
Christofi, FL; Wood, JD	1
Boyet, S; Daval, JL; Nehlig, A	1
Daval, JL; Koziel, V; Nicolas, F; Oillet, J	1
Bonizzoni, E; Casati, C; Dionisotti, S; Monopoli, A; Ongini, E; Zocchi, C	1
Bottrill, FE; Hiley, CR; Richardson, PJ; Warnock, J	1
Kleppisch, T; Nelson, MT	1
Kaneko, S; Mizuno, K; Okada, M	1
Haskó, G; Kvetan, V; Németh, ZH; Pastores, SM; Szabó, C; Vizi, ES	1
Conti, A; Lozza, G; Monopoli, A; Ongini, E	1
Dixon, AK; Richardson, PJ; Widdowson, L	1
Coney, AM; Marshall, JM	1
Baker, SP; Baraldi, PG; Belardinelli, L; Cacciari, B; Monopoli, A; Ongini, E; Shryock, JC; Snowdy, S; Spalluto, G	1
Bryan, PT; Marshall, JM	2
Cutler, BS; Dobson, JG; Fenton, RA; Li, Jm; Peyton, BD; Powell, CC; Wheeler, HB	1
Kaneko, S; Kawata, Y; Kondo, T; Mizuno, K; Murakami, T; Okada, M; Wada, K	1
Bagley, EE; Christie, MJ; Vaughan, CW	1
Jurklies, B; Kaelin-Lang, A; Niemeyer, G	1
Davie, CS; Everitt, DE; Standen, NB	1
Song, WJ; Surmeier, DJ; Tkatch, T	1
Lasley, RD; Narayan, P; Smart, EJ; Uittenbogaard, A	1
Fujita, M; Ito, H; Kohno, Y; Masamune, A; Satoh, A; Satoh, K; Shimosegawa, T; Toyota, T	1
Burgdorf, C; Jain, D; Katus, HA; Kurz, T; Richardt, D; Richardt, G; Seyfarth, M	1
Auchampach, JA; Bhattacharya, S; Black, RG; Bolli, R; Kodani, E; Takano, H; Tang, XL; Yang, Z	1
Bonfanti, A; Marchi, M; Monopoli, A; Ongini, E; Raiteri, L; Raiteri, M; Risso, F; Vallarino, A	1
Belem, PC; Chen, JF; Cronstein, B; Elson, G; Fink, JS; Jacobson, M; Leibovich, SJ; Montesinos, C; Pinhal-Enfield, G; Ramanathan, M; Rosania, A; Schwarzschild, MA	1
Batra, VK; Wilson, CN	1
Dobson, JG; Fenton, RA; Tikh, EI	1
Greengard, P; Higashi, H; Kuroiwa, M; Nishi, A; Shuto, T; Snyder, GL; Sotogaku, N; Tanaka, M; Yabuuchi, K	1
Jacobson, KA; Liang, BT; Wang, R; Wu, D; Zambraski, E; Zheng, J	1
Kawamata, M; Namiki, A; Narimatsu, E; Niiya, T	1
McGuirk, SR; Pardee, AL; Pritchett, CE; Will, MJ	1
Guo, CX; Gupta, R; Housley, GD; Thorne, PR; Vlajkovic, SM; Wong, AC	1

Reviews

2 review(s) available for 2-chloro-n(6)cyclopentyladenosine and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992
Adenosine receptors as therapeutic targets. Nature reviews. Drug discovery, 2006, Volume: 5, Issue:3 Topics: Animals; Disease; Drug Therapy; Humans; Ligands; Molecular Structure; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction; Structure-Activity Relationship	2006

Other Studies

49 other study(ies) available for 2-chloro-n(6)cyclopentyladenosine and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine

Article	Year
2-[N'-(3-arylallylidene)hydrazino]adenosines showing A2a adenosine agonist properties and vasodilation activity. Journal of medicinal chemistry, 1995, Sep-01, Volume: 38, Issue:18 Topics: Adenosine; Animals; Aorta; Hydrazines; In Vitro Techniques; Male; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Structure-Activity Relationship; Vasodilator Agents	1995
2-Aralkynyl and 2-heteroalkynyl derivatives of adenosine-5'-N-ethyluronamide as selective A2a adenosine receptor agonists. Journal of medicinal chemistry, 1995, Apr-28, Volume: 38, Issue:9 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Male; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1	1995
2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors. Journal of medicinal chemistry, 1994, Oct-14, Volume: 37, Issue:21 Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Cell Membrane; CHO Cells; Cricetinae; Molecular Structure; Rats; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship	1994
Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Base Composition; Binding, Competitive; CHO Cells; Cricetinae; Guanylate Cyclase; Humans; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Stereoisomerism; Structure-Activity Relationship; Transfection; Xanthines	1998
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells. Molecular pharmacology, 1999, Volume: 56, Issue:4 Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines	1999
A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Dust; Histamine; Mites; Phosphodiesterase Inhibitors; Purines; Rabbits; Radioligand Assay; Receptor, Adenosine A1	2005
Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity. Journal of medicinal chemistry, 2016, Feb-11, Volume: 59, Issue:3 Topics: Adenosine; Bridged Bicyclo Compounds, Heterocyclic; Cyclopentanes; Dose-Response Relationship, Drug; Drug Discovery; Humans; Molecular Structure; Purinergic P1 Receptor Agonists; Receptor, Adenosine A1; Receptor, Adenosine A3; Structure-Activity Relationship; Substrate Specificity	2016
Polypharmacology of N Journal of medicinal chemistry, 2017, 09-14, Volume: 60, Issue:17 Topics: Adenosine; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adiponectin; Animals; Cell Line; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Male; Mice; Mice, Inbred C57BL; Polypharmacology; PPAR delta; PPAR gamma; Receptor, Adenosine A3	2017
Reduction of postischemic leukocyte-endothelium interaction by adenosine via A2 receptor. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:2 Topics: Adenosine; Animals; Cell Adhesion; Cricetinae; Endothelium, Vascular; Ischemia; Leukocytes; Mesocricetus; Muscles; Phenethylamines; Receptors, Purinergic; Reperfusion Injury; Thioinosine; Xanthines	1992
Intravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction. Circulation, 1992, Volume: 85, Issue:2 Topics: Adenosine; Animals; Coronary Disease; Female; Heart; Hemodynamics; Injections, Intravenous; Male; Myocardial Infarction; Phenethylamines; Phenylisopropyladenosine; Rabbits	1992
The A1 agonist CCPA reduced bisoxonol-monitored membrane potential depolarization elicited by high K+ in cerebrocortical nerve endings. Biochimica et biophysica acta, 1995, Oct-04, Volume: 1239, Issue:1 Topics: Adenosine; Animals; Cerebral Cortex; Fluorescent Dyes; Male; Membrane Potentials; Nerve Endings; Phenethylamines; Potassium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Rats; Rats, Wistar; Synaptosomes; Thiobarbiturates; Triazoles; Veratridine; Xanthines	1995
Biochemical and pharmacological evidence for the presence of A1 but not A2a adenosine receptors in the brain of the low vertebrate teleost Carassius auratus (goldfish). Neurochemistry international, 1995, Volume: 26, Issue:4 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Goldfish; Hydrogen-Ion Concentration; Mammals; Neurotransmitter Agents; Phenethylamines; Radioligand Assay; Receptors, Purinergic P1; Species Specificity; Temperature	1995
Identification of domains of the human A1 adenosine receptor that are important for binding receptor subtype-selective ligands using chimeric A1/A2a adenosine receptors. The Journal of biological chemistry, 1995, Sep-01, Volume: 270, Issue:35 Topics: Adenosine; Analysis of Variance; Animals; Base Sequence; Binding Sites; Binding, Competitive; Cell Line; Chlorocebus aethiops; Humans; Kinetics; Ligands; Molecular Sequence Data; Oligodeoxyribonucleotides; Phenethylamines; Protein Structure, Secondary; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Recombinant Fusion Proteins; Sequence Deletion; Transfection; Tritium; Xanthines	1995
Adenosine attenuates phorbol ester-induced negative inotropic and vasoconstrictive effects in rat hearts. The American journal of physiology, 1994, Volume: 266, Issue:6 Pt 2 Topics: Adenosine; Animals; Coronary Circulation; Diglycerides; Heart; In Vitro Techniques; Indoles; Male; Maleimides; Myocardial Contraction; Perfusion; Phenethylamines; Pressure; Rats; Rats, Wistar; Receptors, Purinergic P1; Tetradecanoylphorbol Acetate; Vasoconstriction	1994
Characterization of the adenosine receptor in microvascular coronary endothelial cells. European journal of pharmacology, 1994, Sep-15, Volume: 269, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Antihypertensive Agents; Cells, Cultured; Colforsin; Coronary Vessels; Cyclic AMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Guinea Pigs; Isoproterenol; Myocardium; Phenethylamines; Phenylisopropyladenosine; Receptors, Purinergic P1; Thioinosine; Vasodilator Agents	1994
Adenosine A1 and A2 receptor agonists alter cardiac functions and prostacyclin release in the isolated guinea-pig heart. European journal of pharmacology, 1994, Oct-03, Volume: 263, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Animals; Antihypertensive Agents; Cardiac Pacing, Artificial; Cells, Cultured; Coronary Circulation; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Guinea Pigs; Heart; Heart Rate; Male; Myocardium; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Triazoles; Vasodilation; Ventricular Function, Left; Xanthines	1994
Electrophysiological subtypes of inhibitory P1 purinoceptors on myenteric neurones of guinea-pig small bowel. British journal of pharmacology, 1994, Volume: 113, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Membrane Potentials; Myenteric Plexus; Phenethylamines; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1	1994
Effects of selective adenosine A1 and A2 receptor agonists and antagonists on local rates of energy metabolism in the rat brain. European journal of pharmacology, 1994, Jun-02, Volume: 258, Issue:1-2 Topics: Adenosine; Animals; Blood Pressure; Brain; Cochlea; Deoxyglucose; Energy Metabolism; Glucose; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Xanthines	1994
Characterization of adenosine receptors in a model of cultured neurons from rat forebrain. Neurochemical research, 1994, Volume: 19, Issue:4 Topics: Adenosine; Adenylyl Cyclases; Aging; Animals; Animals, Newborn; Antihypertensive Agents; Cell Membrane; Cells, Cultured; Embryo, Mammalian; Female; Guanylyl Imidodiphosphate; Kinetics; Neurons; Phenethylamines; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Tritium	1994
Repeated administration of selective adenosine A1 and A2 receptor agonists in the spontaneously hypertensive rat: tolerance develops to A1-mediated hemodynamic effects. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Drug Tolerance; Hemodynamics; Male; Phenethylamines; Rats; Rats, Inbred SHR; Receptors, Purinergic P1	1994
Effects of pH on responses to adenosine, CGS 21680, carbachol and nitroprusside in the isolated perfused superior mesenteric arterial bed of the rat. British journal of pharmacology, 1995, Volume: 116, Issue:6 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Carbachol; Colforsin; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Nitroprusside; Perfusion; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents; Xanthines	1995
Adenosine activates ATP-sensitive potassium channels in arterial myocytes via A2 receptors and cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America, 1995, Dec-19, Volume: 92, Issue:26 Topics: Adenosine; Adenosine Triphosphate; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Glyburide; Isoquinolines; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Phenethylamines; Potassium Channels; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Sulfonamides; Thionucleotides	1995
Adenosine A1 and A2 receptors modulate extracellular dopamine levels in rat striatum. Neuroscience letters, 1996, Jul-05, Volume: 212, Issue:1 Topics: Adenosine; Animals; Antihypertensive Agents; Caffeine; Camptothecin; Dopamine; Enzyme Inhibitors; Extracellular Space; Irinotecan; Male; Microdialysis; Neostriatum; Phenethylamines; Phosphodiesterase Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theobromine; Vasodilator Agents	1996
Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. Journal of immunology (Baltimore, Md. : 1950), 1996, Nov-15, Volume: 157, Issue:10 Topics: Adenosine; Animals; Endotoxemia; Interleukin-10; Macrophages; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Phenethylamines; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Tumor Necrosis Factor-alpha	1996
Cardioprotective effects of adenosine A1 and A2A receptor agonists in the isolated rat heart. Pharmacological research, 1997, Volume: 35, Issue:1 Topics: Adenosine; Analysis of Variance; Animals; Antihypertensive Agents; Creatine Kinase; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Reperfusion Injury; Vasodilator Agents	1997
Desensitisation of the adenosine A1 receptor by the A2A receptor in the rat striatum. Journal of neurochemistry, 1997, Volume: 69, Issue:1 Topics: Adenosine; Animals; Antihypertensive Agents; Corpus Striatum; Enzyme Inhibitors; Isoquinolines; Phenethylamines; Presynaptic Terminals; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sensitivity and Specificity; Sulfonamides; Synaptosomes; Triazines; Triazoles; Tritium; Xanthines	1997
Role of adenosine and its receptors in the vasodilatation induced in the cerebral cortex of the rat by systemic hypoxia. The Journal of physiology, 1998, Jun-01, Volume: 509 ( Pt 2) Topics: Adenosine; Animals; Blood Flow Velocity; Blood-Brain Barrier; Erythrocytes; Hypoxia; Laser-Doppler Flowmetry; Male; Parietal Lobe; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilation	1998
A2A-adenosine receptor reserve for coronary vasodilation. Circulation, 1998, Aug-18, Volume: 98, Issue:7 Topics: Adenosine; Animals; Coronary Circulation; Female; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Triazines; Triazoles; Vasodilation	1998
Adenosine receptor subtypes and vasodilatation in rat skeletal muscle during systemic hypoxia: a role for A1 receptors. The Journal of physiology, 1999, Jan-01, Volume: 514 ( Pt 1) Topics: Adenosine; Animals; Antihypertensive Agents; Blood Gas Analysis; Hydrogen-Ion Concentration; Hypoxia; Male; Muscle, Skeletal; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Respiration; Triazines; Triazoles; Vasodilation; Vasodilator Agents; Xanthines	1999
Cellular mechanisms by which adenosine induces vasodilatation in rat skeletal muscle: significance for systemic hypoxia. The Journal of physiology, 1999, Jan-01, Volume: 514 ( Pt 1) Topics: Adenosine; Animals; Antihypertensive Agents; Blood Pressure; Cromakalim; Enzyme Inhibitors; Femoral Artery; Glyburide; Heart Rate; Hypoglycemic Agents; Hypoxia; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitroprusside; Phenethylamines; Potassium Channel Blockers; Potassium Channels; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Regional Blood Flow; Vasodilator Agents	1999
Adenosine A2a receptors increase arterial endothelial cell nitric oxide. The Journal of surgical research, 1998, Volume: 80, Issue:2 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carotid Arteries; Cells, Cultured; Endothelium, Vascular; Humans; Iliac Artery; Nitric Oxide; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Swine; Triazines; Triazoles; Xanthines	1998
Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin. The European journal of neuroscience, 1999, Volume: 11, Issue:1 Topics: Adenosine; Animals; Antihypertensive Agents; Biological Transport; Caffeine; Central Nervous System Stimulants; Fluoxetine; Hippocampus; Male; Microdialysis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quipazine; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Theobromine; Theophylline; Vasodilator Agents	1999
Inhibition by adenosine receptor agonists of synaptic transmission in rat periaqueductal grey neurons. The Journal of physiology, 1999, Apr-01, Volume: 516 ( Pt 1) Topics: Action Potentials; Adenosine; Animals; Colforsin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Periaqueductal Gray; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synaptic Transmission	1999
Effects of adenosinergic agents on the vascular resistance and on the optic nerve response in the perfused cat eye. Vision research, 1999, Volume: 39, Issue:6 Topics: Adenosine; Animals; Cats; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Electrophysiology; Female; Optic Nerve; Perfusion; Phenethylamines; Photic Stimulation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Retina; Theobromine; Theophylline; Vascular Resistance	1999
Increase in the vasorelaxant potency of K(ATP) channel opening drugs by adenosine A(1) and A(2) receptors in the pig coronary artery. European journal of pharmacology, 1999, Oct-27, Volume: 383, Issue:2 Topics: Adenosine; Animals; ATP-Binding Cassette Transporters; Coronary Vessels; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; KATP Channels; Nicorandil; Phenethylamines; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Swine; Triazines; Triazoles; Vasodilator Agents; Xanthines	1999
Adenosine receptor expression and modulation of Ca(2+) channels in rat striatal cholinergic interneurons. Journal of neurophysiology, 2000, Volume: 83, Issue:1 Topics: Adenosine; Animals; Calcium Channels, N-Type; Choline O-Acetyltransferase; Corpus Striatum; Ethylmaleimide; GTP-Binding Proteins; Guanosine Diphosphate; In Vitro Techniques; Interneurons; Membrane Potentials; Patch-Clamp Techniques; Phenethylamines; Rats; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theophylline; Thionucleotides	2000
Activated cardiac adenosine A(1) receptors translocate out of caveolae. The Journal of biological chemistry, 2000, Feb-11, Volume: 275, Issue:6 Topics: Adenosine; Animals; Biomarkers; Caveolin 3; Caveolins; Cell Membrane; Cells, Cultured; Cholesterol; Male; Membrane Proteins; Microscopy, Immunoelectron; Myocardium; Nitric Oxide Synthase; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines	2000
Activation of adenosine A1-receptor pathway induces edema formation in the pancreas of rats. Gastroenterology, 2000, Volume: 119, Issue:3 Topics: Acute Disease; Adenosine; Amylases; Animals; Ceruletide; Edema; Leukocytes; Male; Pancreas; Pancreatic Diseases; Pancreatitis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptor, Adenosine A3; Receptors, Purinergic P1; Taurocholic Acid	2000
Adenosine inhibits norepinephrine release in the postischemic rat heart: the mechanism of neuronal stunning. Cardiovascular research, 2001, Volume: 49, Issue:4 Topics: Adenosine; Analysis of Variance; Animals; Brimonidine Tartrate; Electric Stimulation; Enzyme Inhibitors; Male; Myocardial Stunning; Myocardium; Norepinephrine; Perfusion; Phenethylamines; Phenylisopropyladenosine; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Quinoxalines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Sympathetic Nervous System; Theophylline; Time Factors; Xanthines	2001
A(1) or A(3) adenosine receptors induce late preconditioning against infarction in conscious rabbits by different mechanisms. Circulation research, 2001, Mar-16, Volume: 88, Issue:5 Topics: Adenine; Adenosine; Animals; Binding, Competitive; Cell Line; Consciousness; Decanoic Acids; Humans; Hydroxy Acids; Iodine Radioisotopes; Ischemic Preconditioning, Myocardial; Membranes; Myocardial Infarction; Nitroarginine; Norbornanes; Phenethylamines; Rabbits; Radioligand Assay; Receptor, Adenosine A3; Receptors, Purinergic P1	2001
Effects of adenosine A1 and A2A receptor activation on the evoked release of glutamate from rat cerebrocortical synaptosomes. British journal of pharmacology, 2002, Volume: 136, Issue:3 Topics: Adenosine; Analysis of Variance; Animals; Cerebral Cortex; Chromatography, High Pressure Liquid; Glutamic Acid; In Vitro Techniques; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Synaptosomes; Triazoles; Xanthines	2002
Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin. The American journal of pathology, 2002, Volume: 160, Issue:6 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Cells, Cultured; Drosophila Proteins; Endothelial Growth Factors; Female; Interferon-gamma; Lipopolysaccharides; Lymphokines; Macrophages, Peritoneal; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phenethylamines; Protein Kinase Inhibitors; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptors, Cell Surface; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Theobromine; Toll-Like Receptor 4; Toll-Like Receptors; Triazines; Triazoles; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Xanthines	2002
Lipopolysaccharide binds to and activates A(1) adenosine receptors on human pulmonary artery endothelial cells. Journal of endotoxin research, 2002, Volume: 8, Issue:4 Topics: Adenosine; Binding, Competitive; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Glycolipids; Gram-Negative Bacteria; Humans; Interleukin-6; Lipid A; Lipopolysaccharides; Phenethylamines; Pulmonary Artery; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptors, Purinergic P1; Thromboxane A2; Xanthines	2002
Contractile effects of adenosine A1 and A2A receptors in isolated murine hearts. American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:1 Topics: Adenosine; Animals; Heart; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Ischemia; Phenethylamines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Xanthines	2006
Role of adenosine A1 receptors in the modulation of dopamine D1 and adenosine A2A receptor signaling in the neostriatum. Neuroscience, 2006, Aug-11, Volume: 141, Issue:1 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Benzazepines; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Antagonists; Drug Interactions; Gene Expression; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neostriatum; Phenethylamines; Raclopride; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Dopamine D1; Signal Transduction; Threonine; Triazines; Triazoles; Xanthines	2006
Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:6 Topics: Adenosine; Animals; Dihydropyridines; Disease Models, Animal; Hindlimb; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Phenethylamines; Phospholipase C beta; Pyrazoles; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Reperfusion Injury; Signal Transduction; Xanthines	2007
Adenosine and adenosine uptake inhibitors potentiate the neuromuscular blocking action of rocuronium mediated by adenosine A(1) receptors in isolated rat diaphragms. Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:10 Topics: Adenosine; Adenosine A1 Receptor Agonists; Androstanols; Animals; Diaphragm; Dipyridamole; Drug Synergism; Electric Stimulation; Male; Midazolam; Models, Animal; Neuromuscular Blocking Agents; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A1; Rocuronium; Xanthines	2008
The role of nucleus accumbens adenosine-opioid interaction in mediating palatable food intake. Brain research, 2010, Jan-08, Volume: 1306 Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Catheterization; Central Nervous System Agents; Dietary Fats; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Locomotion; Male; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Opioid, mu; Xanthines	2010
Post exposure administration of A(1) adenosine receptor agonists attenuates noise-induced hearing loss. Hearing research, 2010, Volume: 260, Issue:1-2 Topics: Acoustic Stimulation; Adenosine; Adenosine A1 Receptor Agonists; Animals; Auditory Threshold; Cochlea; Cochlear Microphonic Potentials; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Hearing Loss, Noise-Induced; Male; Oxidative Stress; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A1; Time Factors; Tyrosine	2010

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