Compounds > 2-chloro-2',3'-dideoxyadenosine
Page last updated: 2024-08-25

2-chloro-2',3'-dideoxyadenosine and dideoxyadenosine

2-chloro-2',3'-dideoxyadenosine has been researched along with dideoxyadenosine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rosowsky, A; Ruprecht, RM; Sodroski, JG; Solan, VC1
Chapman, DE; Powis, G1
Carrera, CJ; Carson, DA; Haertle, T; Richman, DD; Sowers, LC; Wasson, DB1
Charlap, JH; Donahue, RJ; Knudsen, TB1
Gewirth, DT; Jivan, A; Nicchitta, CV; Soldano, KL1

Other Studies

5 other study(ies) available for 2-chloro-2',3'-dideoxyadenosine and dideoxyadenosine

ArticleYear
Synthesis of the 2-chloro analogues of 3'-deoxyadenosine, 2',3'-dideoxyadenosine, and 2',3'-didehydro-2',3'-dideoxyadenosine as potential antiviral agents.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:5

    Topics: 2-Chloroadenosine; Animals; Antiviral Agents; Deoxyadenosines; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; Mice; Structure-Activity Relationship

1989
Disposition and metabolism in mice of the potential antitumor and anti-human immunodeficiency virus-1 agent, 2-chloro-2',3'-dideoxyadenosine.
    Cancer chemotherapy and pharmacology, 1991, Volume: 27, Issue:4

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Blood Proteins; Chromatography, High Pressure Liquid; Deamination; Dideoxyadenosine; Half-Life; HIV-1; Male; Mice; Protein Binding

1991
Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2',3'-dideoxyadenosine derivatives.
    The Journal of biological chemistry, 1988, Apr-25, Volume: 263, Issue:12

    Topics: Adenosine Deaminase Inhibitors; AMP Deaminase; Cell Line; Coformycin; Deoxyadenosines; Deoxycytidine Kinase; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; Phosphorylation; T-Lymphocytes; Virus Replication

1988
Exposure-disease continuum for 2-chloro-2'-deoxyadenosine, a prototype ocular teratogen. 3. Intervention with PK11195.
    Birth defects research. Part A, Clinical and molecular teratology, 2003, Volume: 67, Issue:2

    Topics: Animals; Dideoxyadenosine; Drug Evaluation, Preclinical; Eye Abnormalities; Female; Fetal Proteins; Fetal Resorption; Fetus; Gene Expression Regulation, Developmental; Genes, p53; Gestational Age; Isoquinolines; Mice; Microphthalmos; Mitochondria; NAD; Pregnancy; Receptors, GABA-A; RNA, Ribosomal, 16S; Teratogens; Tumor Suppressor Protein p53

2003
Structure of the N-terminal domain of GRP94. Basis for ligand specificity and regulation.
    The Journal of biological chemistry, 2003, Nov-28, Volume: 278, Issue:48

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Crystallography, X-Ray; Cytoplasm; Dideoxyadenosine; Dimerization; Dogs; Electrons; Endoplasmic Reticulum; Glutathione Transferase; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Lactones; Ligands; Macrolides; Membrane Proteins; Models, Chemical; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Substrate Specificity

2003