2-chloro-11-(4-methyl-1-piperazinyl)-5h-dibenzo(b,e)(1,4)diazepine has been researched along with clozapine in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, DA; de Paulis, T; Janowsky, A; Smith, HE | 1 |
| de Paulis, T; Janowsky, A; Rupard, JH; Smith, HE | 1 |
| Harris, TW; Manier, DH; Mobley, PL; Smith, HE; Sulser, F | 1 |
| Betts, CR; de Paulis, T; Manier, DH; Mobley, PL; Smith, HE; Sulser, F | 1 |
| Bruhwyler, J; Chleide, EM; Damas, J; Delarge, JE; Inarejos, MO; Liégeois, JF; Mercier, MG; Nguyen, TP; Rogister, FA | 1 |
| Baron, BM; de Paulis, T; Guan, HC; Phillips, ST; Seeman, P; Siegel, BW; Smith, HE; Van Tol, HH | 1 |
| Bruhwyler, J; Chleide, EM; Damas, J; Delarge, JE; Liégeois, JF; Mercier, MG; Nguyen, TP; Rogister, FA | 1 |
| DeBoer, P; Liao, Y; Meier, E; Wikström, H | 1 |
| Bartoszyk, GD; Böttcher, H; Liao, Y; Meier, E; Rodenhuis, N; Seyfried, CA; Sundell, S; Timmerman, W; Venhuis, BJ; Wikström, H | 1 |
| Butini, S; Cagnotto, A; Campiani, G; Carli, M; Carminati, P; Castorina, M; Catalanotti, B; Di Cesare, MA; Di Serio, S; Fattorusso, C; Galletti, B; Gemma, S; Ghirardi, O; Mastroianni, D; Mennini, T; Mereghetti, I; Minetti, P; Morelli, E; Nacci, V; Pacifici, L; Scafetta, N; Stasi, MA; Tinti, O; Vertechy, M | 1 |
| Spealman, RD | 1 |
11 other study(ies) available for 2-chloro-11-(4-methyl-1-piperazinyl)-5h-dibenzo(b,e)(1,4)diazepine and clozapine
| Article | Year |
|---|---|
Chloro-substituted, sterically hindered 5,11-dicarbo analogues of clozapine as potential chiral antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Clozapine; Dibenzazepines; In Vitro Techniques; Magnetic Resonance Spectroscopy; Motion; Rats; Receptors, Dopamine; Receptors, Muscarinic; Structure-Activity Relationship | 1990 |
Sterically hindered 5,11-dicarbo analogues of clozapine as potential chiral antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Cerebral Cortex; Clozapine; Corpus Striatum; Dibenzazepines; Indicators and Reagents; Magnetic Resonance Spectroscopy; Molecular Structure; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Muscarinic; Structure-Activity Relationship | 1989 |
Affinity of 10-(4-methylpiperazino)dibenz[b,f]oxepins for clozapine and spiroperidol binding sites in rat brain.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Butyrophenones; Caudate Nucleus; Clozapine; Dibenzazepines; Dibenzoxepins; In Vitro Techniques; Rats; Spiperone | 1982 |
Synthesis of clozapine analogues and their affinity for clozapine and spiroperidol binding sites in rat brain.
Topics: Animals; Binding Sites; Brain; Chemical Phenomena; Chemistry; Clozapine; Dibenzazepines; In Vitro Techniques; Kinetics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Spiperone | 1981 |
Pyridobenzoxazepine and pyridobenzothiazepine derivatives as potential central nervous system agents: synthesis and neurochemical study.
Topics: Animals; Antipsychotic Agents; Binding Sites; Dogs; Oxazepines; Pyridines; Rats; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Serotonin; Structure-Activity Relationship; Thiazepines | 1994 |
Binding of 5H-dibenzo[b,e][1,4]diazepine and chiral 5H-dibenzo[a,d]cycloheptene analogues of clozapine to dopamine and serotonin receptors.
Topics: Animals; Cell Line; Cell Membrane; Clozapine; Crystallography, X-Ray; Dibenzazepines; Dibenzocycloheptenes; Dopamine; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Optical Rotation; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 1994 |
New pyridobenzodiazepine derivatives as potential antipsychotics: synthesis and neurochemical study.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Binding Sites; Dogs; Rats; Structure-Activity Relationship | 1993 |
Synthesis and pharmacological evaluation of triflate-substituted analogues of clozapine: identification of a novel atypical neuroleptic.
Topics: Animals; Antipsychotic Agents; Clozapine; Male; Rats; Rats, Wistar; Structure-Activity Relationship | 1997 |
New (sulfonyloxy)piperazinyldibenzazepines as potential atypical antipsychotics: chemistry and pharmacological evaluation.
Topics: Animals; Antipsychotic Agents; Benzazepines; Brain; Catalepsy; CHO Cells; Cricetinae; Dopamine Antagonists; Humans; In Vitro Techniques; Male; Mice; Molecular Structure; Piperazines; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Histamine H1; Receptors, Muscarinic; Receptors, Serotonin; Structure-Activity Relationship | 1999 |
Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Benzothiepins; Catalepsy; Cognition Disorders; Dopamine Antagonists; Humans; Male; Mice; Models, Molecular; Motor Activity; Pituitary Gland, Anterior; Prolactin; Pyrroles; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Serotonin, 5-HT2; Serotonin Antagonists; Structure-Activity Relationship; Thiazepines | 2004 |
Effects of some dibenzo-azepines on suppressed and nonsuppressed behavior of squirrel monkeys.
Topics: Animals; Behavior, Animal; Clozapine; Dibenzazepines; Dibenzothiazepines; Inhibition, Psychological; Loxapine; Male; Saimiri; Structure-Activity Relationship | 1985 |