Compounds > 2-carboxyarabinitol 1-phosphate
Page last updated: 2024-09-03

2-carboxyarabinitol 1-phosphate and gsk 1363089

2-carboxyarabinitol 1-phosphate has been researched along with gsk 1363089 in 4 studies

Compound Research Comparison

Studies
(2-carboxyarabinitol 1-phosphate)		Trials
(2-carboxyarabinitol 1-phosphate)		Recent Studies (post-2010)
(2-carboxyarabinitol 1-phosphate)		Studies
(gsk 1363089)		Trials
(gsk 1363089)		Recent Studies (post-2010) (gsk 1363089)
170131319124

Protein Interaction Comparison

ProteinTaxonomy2-carboxyarabinitol 1-phosphate (IC50)gsk 1363089 (IC50)
Epidermal growth factor receptorHomo sapiens (human)1.5147
High affinity nerve growth factor receptorHomo sapiens (human)0.003
Acyl-CoA desaturase 1Rattus norvegicus (Norway rat)0.0004
Hepatocyte growth factor receptorHomo sapiens (human)0.056
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)0.01
Platelet-derived growth factor receptor betaHomo sapiens (human)0.0098
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.1814
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.2346
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.2541
Ephrin type-A receptor 2Homo sapiens (human)0.0019
Tyrosine-protein kinase receptor UFOHomo sapiens (human)0.0417
Delta-type opioid receptorMus musculus (house mouse)0.0049
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.003
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.1234
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.1806
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)2.99
Mu-type opioid receptorMus musculus (house mouse)0.0056
4-aminobutyrate aminotransferase, mitochondrialMus musculus (house mouse)0.0086
Angiopoietin-1 receptorHomo sapiens (human)0.0011
Macrophage-stimulating protein receptorHomo sapiens (human)0.1798
Homeodomain-interacting protein kinase 1Homo sapiens (human)0.1
Cyclin-dependent kinase-like 3Homo sapiens (human)7.9
Homeodomain-interacting protein kinase 4Homo sapiens (human)0.1
Homeodomain-interacting protein kinase 2Homo sapiens (human)0.1
Homeodomain-interacting protein kinase 3Homo sapiens (human)0.1
ALK tyrosine kinase receptorHomo sapiens (human)3.18

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Gong, P; Mi, B; Qi, B; Tian, Z; Xu, Z; Zhai, X; Zhang, X1
Bao, G; Du, B; Gong, P; Li, W; Lv, J; Ma, J; Wang, L; Xu, B; Zhai, X1
Bao, G; Cheng, M; Gong, P; Wang, L; Zhai, X; Zhao, M; Zhao, S; Zhou, H1

Other Studies

4 other study(ies) available for 2-carboxyarabinitol 1-phosphate and gsk 1363089

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Discovery and optimization of novel 4-phenoxy-6,7-disubstituted quinolines possessing semicarbazones as c-Met kinase inhibitors.
    Bioorganic & medicinal chemistry, 2013, Sep-01, Volume: 21, Issue:17

    Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Molecular Docking Simulation; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-met; Quinolines; Semicarbazides; Semicarbazones; Structure-Activity Relationship

2013
Design, synthesis, biological evaluation and preliminary mechanism study of novel benzothiazole derivatives bearing indole-based moiety as potent antitumor agents.
    European journal of medicinal chemistry, 2015, Volume: 96

    Topics: Antineoplastic Agents; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Indoles; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship

2015
Design, synthesis and biological evaluation of novel 4-phenoxy-6,7-disubstituted quinolines possessing (thio)semicarbazones as c-Met kinase inhibitors.
    Bioorganic & medicinal chemistry, 2016, Mar-15, Volume: 24, Issue:6

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Mice; Molecular Structure; Neoplasms, Experimental; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Quinolines; Semicarbazones; Structure-Activity Relationship

2016