2-bromomelatonin has been researched along with 6-chloromelatonin in 6 studies
| Studies (2-bromomelatonin) | Trials (2-bromomelatonin) | Recent Studies (post-2010) (2-bromomelatonin) | Studies (6-chloromelatonin) | Trials (6-chloromelatonin) | Recent Studies (post-2010) (6-chloromelatonin) |
|---|---|---|---|---|---|
| 9 | 0 | 1 | 62 | 0 | 11 |
| Protein | Taxonomy | 2-bromomelatonin (IC50) | 6-chloromelatonin (IC50) |
|---|---|---|---|
| Melatonin receptor type 1A | Homo sapiens (human) | 0.0024 | |
| Melatonin receptor type 1B | Homo sapiens (human) | 0.0024 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Biella, G; Duranti, A; Fraschini, F; Lucini, V; Salvatori, A; Spadoni, G; Stankov, B | 1 |
| Balsamini, C; Di Giacomo, B; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Pannacci, M; Plazzi, PV; Rivara, S; Spadoni, G; Stankov, BM; Tarzia, G | 1 |
| Di Giacomo, B; Diamantini, G; Esposti, D; Fraschini, F; Lucini, V; Nonno, R; Pannacci, M; Spadoni, G; Stankov, BM; Tarzia, G | 1 |
| Balsamini, C; Bordi, F; Diamantini, G; Fraschini, F; Lucini, V; Mor, M; Nonno, R; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Stankov, BM; Tarzia, G | 1 |
| Bedini, A; Fraschini, F; Lucini, V; Mor, M; Pannacci, M; Plazzi, PV; Rivara, S; Silva, C; Spadoni, G; Tarzia, G; Vacondio, F; Zuliani, V | 1 |
| Laborda, P; Shi, XC; Wang, SY | 1 |
1 review(s) available for 2-bromomelatonin and 6-chloromelatonin
| Article | Year |
|---|---|
Indole-based melatonin analogues: Synthetic approaches and biological activity.
Topics: Animals; Dose-Response Relationship, Drug; Humans; Indoles; Ligands; Melatonin; Molecular Structure; Receptors, Melatonin; Structure-Activity Relationship | 2020 |
5 other study(ies) available for 2-bromomelatonin and 6-chloromelatonin
| Article | Year |
|---|---|
2-Substituted 5-methoxy-N-acyltryptamines: synthesis, binding affinity for the melatonin receptor, and evaluation of the biological activity.
Topics: Animals; Binding Sites; Cricetinae; Male; Mesocricetus; Quail; Rabbits; Receptors, Cell Surface; Receptors, Melatonin; Structure-Activity Relationship; Tryptamines | 1993 |
Conformationally restrained melatonin analogues: synthesis, binding affinity for the melatonin receptor, evaluation of the biological activity, and molecular modeling study.
Topics: Animals; Binding, Competitive; Chickens; Colforsin; Cyclic AMP; Drug Design; Guanosine 5'-O-(3-Thiotriphosphate); Melatonin; Models, Molecular; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Superior Colliculi | 1997 |
1-(2-Alkanamidoethyl)-6-methoxyindole derivatives: a new class of potent indole melatonin analogues.
Topics: Animals; Binding Sites; Binding, Competitive; Chickens; Colforsin; Cyclic AMP; Drug Design; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Melatonin; Models, Chemical; Quail; Superior Colliculi | 1997 |
Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study.
Topics: Animals; Ligands; Melatonin; Models, Molecular; Molecular Conformation; Quail; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Structure-Activity Relationship; Superior Colliculi | 1998 |
Three-dimensional quantitative structure-activity relationship studies on selected MT1 and MT2 melatonin receptor ligands: requirements for subtype selectivity and intrinsic activity modulation.
Topics: Ligands; Melatonin; Models, Molecular; Models, Statistical; Pyrroles; Quantitative Structure-Activity Relationship; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin | 2003 |