2-aminopyrimidine has been researched along with alpha-aminopyridine in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boehm, HJ; Boehringer, M; Bur, D; Gmuender, H; Huber, W; Klaus, W; Kostrewa, D; Kuehne, H; Luebbers, T; Meunier-Keller, N; Mueller, F | 1 |
| Booker, GW; Branson, KM; Cawthray, JF; Fritz, D; Inglis, SR; Pyke, SM; Stojkoski, C; Wiadrowski, E | 1 |
| Aoki, Y; Fukami, TA; Hasegawa, K; Kim, SJ; Miura, T; Na, YJ; Ono, N; Shimma, N; Shindo, H; Shiratori, Y; Suda, A; Tsukuda, T; Yoon, DO | 1 |
| Ackermann, B; Erdel, V; Ferner, J; Göbel, MW; Kalden, E; Scheffer, U; Schwalbe, H; Shoja-Bazargani, F; Stark, S; Zeiger, M | 1 |
| Campbell, Y; Cardellina, JH; Eccard, VS; Ensel, SM; Guernieri, R; Harrell, WA; Montgomery, V; Roxas-Duncan, V; Smith, LA; Vieira, RC; Webb, RP | 1 |
| Bach, A; Bucciarelli, S; Gotfredsen, CH; Høj, LJ; Langkilde, AE; Meier, S; Narayanan, D; Sattler, M; Softley, C; Solbak, SMØ; Zang, J | 1 |
| Abdel-Latif, SA; Hassib, HB; Issa, YM | 1 |
| Gallagher, JF; Mocilac, P | 1 |
| Al-Mourabit, A; Corbin, M; Ermolenko, L; Nguyen, TB; Retailleau, P | 1 |
| Alcaro, S; Bagetta, D; Bortolami, M; Carafa, C; Chiarotto, I; Colone, M; Costi, R; De Vita, D; Di Santo, R; Feroci, M; Messore, A; Pandolfi, F; Scipione, L; Stringaro, A | 1 |
10 other study(ies) available for 2-aminopyrimidine and alpha-aminopyridine
| Article | Year |
|---|---|
Novel inhibitors of DNA gyrase: 3D structure based biased needle screening, hit validation by biophysical methods, and 3D guided optimization. A promising alternative to random screening.
Topics: Anti-Infective Agents; Coumarins; Crystallography, X-Ray; DNA Topoisomerases, Type II; Enzyme Inhibitors; Indazoles; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Novobiocin; Protein Binding; Structure-Activity Relationship; Surface Plasmon Resonance; Topoisomerase II Inhibitors; Ultracentrifugation | 2000 |
Identification and specificity studies of small-molecule ligands for SH3 protein domains.
Topics: Amino Acid Sequence; Aminoquinolines; Animals; Binding Sites; Binding, Competitive; Fluorescence Polarization; Ligands; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Protein-Tyrosine Kinases; Quinazolines; Sequence Alignment; src Homology Domains; Structure-Activity Relationship | 2004 |
Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design.
Topics: Adenosine Triphosphatases; Administration, Oral; Animals; Antineoplastic Agents; Benzopyrans; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Drug Discovery; Escherichia coli; HSP90 Heat-Shock Proteins; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Neoplasms; Reproducibility of Results; Structure-Activity Relationship; Surface Plasmon Resonance; Triazines; Xenograft Model Antitumor Assays | 2011 |
Fragment based search for small molecule inhibitors of HIV-1 Tat-TAR.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; HIV Long Terminal Repeat; HIV-1; Humans; Ligands; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; RNA, Viral; Small Molecule Libraries; tat Gene Products, Human Immunodeficiency Virus | 2014 |
A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum neurotoxin serotype A.
Topics: Animals; Binding Sites; Botulinum Toxins, Type A; Hydroxyquinolines; Inhibitory Concentration 50; Mice; Phrenic Nerve; Protein Binding; Serogroup; Structure-Activity Relationship | 2017 |
Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery.
Topics: Azoles; Drug Discovery; Humans; Indoles; Isoindoles; Molecular Structure; NADPH Oxidase 2; NADPH Oxidases; Organoselenium Compounds; Protein Binding; Structure-Activity Relationship | 2020 |
Studies on some salicylaldehyde Schiff base derivatives and their complexes with Cr(III), Mn(II), Fe(III), Ni(II) and Cu(II).
Topics: 4-Aminopyridine; Aldehydes; Aminopyridines; Aniline Compounds; Chromium; Copper; Electron Probe Microanalysis; Ethanol; Hydrogen-Ion Concentration; Iron; Kinetics; Manganese; Molecular Structure; Nickel; Nitrogen; Pyrimidines; Schiff Bases; Solvents; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Thermogravimetry; Transition Elements | 2007 |
Trezimides and tennimides: new imide-based macrocycles.
Topics: Aminopyridines; Crystallography, X-Ray; Imides; Macrocyclic Compounds; Models, Molecular; Molecular Conformation; Phthalic Acids; Polymers; Pyrimidines | 2013 |
Elements as Direct Feedstocks for Organic Synthesis: Fe/I2/O2 for Diamination of 2-Cyclohexenones with 2-Aminopyrimidine and 2-Aminopyridines.
Topics: Amination; Aminopyridines; Catalysis; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Cyclohexanones; Iron; Molecular Conformation; Molecular Structure; Oxidation-Reduction; Oxygen; Pyrimidines | 2015 |
New deferiprone derivatives as multi-functional cholinesterase inhibitors: design, synthesis and in vitro evaluation.
Topics: Acetylcholinesterase; Alzheimer Disease; Amines; Amino Acid Sequence; Aminopyridines; Catalytic Domain; Cholinesterase Inhibitors; Coordination Complexes; Deferiprone; Drug Design; Humans; Iron Chelating Agents; Molecular Docking Simulation; Pyrimidines; Structure-Activity Relationship | 2020 |