Page last updated: 2024-08-21

2-aminopurine and hypoxanthine

2-aminopurine has been researched along with hypoxanthine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's6 (37.50)18.2507
2000's5 (31.25)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brereton, IM; de Jersey, J; Guddat, LW; Jones, MK; Keough, DT; Ng, AL; Skinner-Adams, T1
Carlson, EE; Goswami, M; Wilke, KE1
Akiyama, Y; Hashimoto, H; Kitoh, T; Kubota, M; Mikawa, H; Shimizu, T; Takimoto, T1
Adamson, DJ; Bennett, LL; Brockman, RW; Rose, LM; Smithers, D1
Cano, A; DuBois, S; Eritja, R; Guschlbauer, W; Marzabal, S; Thielking, V1
Alvarez-Builla, J; Burgos, C; Gago, F; Gallego, J; Luque, FJ; Orozco, M; Rodrigo, MM1
Beigelman, L; Herschlag, D; Peracchi, A; Usman, N1
Jennewein, S; Waring, MJ1
Dubois, S; Eritja, R; Guschlbauer, W; Thielking, V1
DUNCAN, RE; SETTERFIELD, G1
Koshkin, AA1
Arar, K; Gamper, HB; Gewirtz, A; Hou, YM1
Matsika, S; Mburu, E1
Ivanova, E; Wang, F; Zhu, Q1
Hornum, M; Kumar, P; Nielsen, P; Nielsen, RB; Petersen, M; Sharma, PK; Stendevad, J1
Chen, J; Pang, L; Wang, X; Zhang, JZH; Zhu, T1

Other Studies

16 other study(ies) available for 2-aminopurine and hypoxanthine

ArticleYear
Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases.
    Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25

    Topics: Animals; Antimalarials; Guanine; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Pentosyltransferases; Plasmodium falciparum; Purines; Structure-Activity Relationship

2006
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
    Journal of medicinal chemistry, 2017, 10-12, Volume: 60, Issue:19

    Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship

2017
Biochemical basis of the prevention of 6-thiopurine toxicity by the nucleobases, hypoxanthine and adenine.
    Leukemia research, 1990, Volume: 14, Issue:11-12

    Topics: 2-Aminopurine; Adenine; Adenine Phosphoribosyltransferase; Antineoplastic Agents; Biological Transport; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Inosine Monophosphate; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Promyelocytic, Acute; Mercaptopurine; Thioguanine; Thionucleotides; Tumor Cells, Cultured

1990
Mode of action of 2-amino-6-chloro-1-deazapurine.
    Biochemical pharmacology, 1984, Jan-15, Volume: 33, Issue:2

    Topics: 2-Aminopurine; Adenine; AMP Deaminase; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Glycine; Humans; Hypoxanthine; Hypoxanthines; IMP Dehydrogenase; Laryngeal Neoplasms; Leukemia L1210; Macromolecular Substances; Mice; Nucleotides; Ribonucleotides; Structure-Activity Relationship

1984
Dam methylase from Escherichia coli: kinetic studies using modified DNA oligomers: hemimethylated substrates.
    Nucleic acids research, 1995, Sep-25, Volume: 23, Issue:18

    Topics: 2-Aminopurine; Base Sequence; DNA; Escherichia coli; Escherichia coli Proteins; Hypoxanthine; Hypoxanthines; Kinetics; Methylation; Molecular Sequence Data; Nucleic Acid Denaturation; Polydeoxyribonucleotides; Site-Specific DNA-Methyltransferase (Adenine-Specific); Thermodynamics; Uracil

1995
DNA sequence-specific reading by echinomycin: role of hydrogen bonding and stacking interactions.
    Journal of medicinal chemistry, 1994, May-27, Volume: 37, Issue:11

    Topics: 2-Aminopurine; Base Composition; Base Sequence; Binding Sites; Chemical Phenomena; Chemistry, Physical; Deoxyribonuclease I; DNA; Echinomycin; Electrochemistry; Hydrogen Bonding; Hypoxanthine; Hypoxanthines; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Quinoxalines; Thermodynamics

1994
Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Oct-15, Volume: 93, Issue:21

    Topics: 2-Aminopurine; Base Composition; Base Sequence; Guanine; Hypoxanthine; Indicators and Reagents; Kinetics; Nucleic Acid Conformation; Oligoribonucleotides; RNA, Catalytic

1996
Footprinting of echinomycin and actinomycin D on DNA molecules asymmetrically substituted with inosine and/or 2,6-diaminopurine.
    Nucleic acids research, 1997, Apr-15, Volume: 25, Issue:8

    Topics: 2-Aminopurine; Base Composition; Binding Sites; Cytosine; Dactinomycin; DNA; DNA Footprinting; DNA Primers; Echinomycin; Hydrogen Bonding; Hypoxanthine; Inosine; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Thymine

1997
Dam methyltransferase from Escherichia coli: kinetic studies using modified DNA oligomers: nonmethylated substrates.
    Biological chemistry, 1997, Volume: 378, Issue:5

    Topics: 2-Aminopurine; Adenine; Base Sequence; DNA Methylation; DNA Probes; DNA, Bacterial; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Guanine; Hypoxanthine; Kinetics; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Oligonucleotide Probes; Site-Specific DNA-Methyltransferase (Adenine-Specific); Software; Substrate Specificity; Temperature; Thermodynamics; Thymine; Uracil

1997
Cytological studies on the antimetabolite action of 2, 6-diaminopurine in Vicia faba roots.
    The Journal of biophysical and biochemical cytology, 1955, Sep-25, Volume: 1, Issue:5

    Topics: 2-Aminopurine; Adenine; Adenosine; Antimetabolites; Cell Division; Deoxyadenosines; DNA; Growth; Guanine; Hypoxanthine; Purines; Vicia faba

1955
Syntheses and base-pairing properties of locked nucleic acid nucleotides containing hypoxanthine, 2,6-diaminopurine, and 2-aminopurine nucleobases.
    The Journal of organic chemistry, 2004, May-28, Volume: 69, Issue:11

    Topics: 2-Aminopurine; Base Pairing; Hypoxanthine; Nucleic Acid Conformation; Oligonucleotides; Oligonucleotides, Antisense

2004
Unrestricted accessibility of short oligonucleotides to RNA.
    RNA (New York, N.Y.), 2005, Volume: 11, Issue:9

    Topics: 2-Aminopurine; Base Pairing; Guanine; Hypoxanthine; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotides; RNA; RNA Probes; Temperature; Thiouracil

2005
An ab initio study of substituent effects on the excited states of purine derivatives.
    The journal of physical chemistry. A, 2008, Dec-04, Volume: 112, Issue:48

    Topics: 2-Aminopurine; Adenine; Electrons; Gases; Guanine; Hypoxanthine; Isomerism; Purines; Quantum Theory; Xanthine

2008
Impact of ketone and amino on the inner shell of guanine.
    Journal of synchrotron radiation, 2009, Volume: 16, Issue:Pt 4

    Topics: 2-Aminopurine; DNA; Guanine; Hypoxanthine; Models, Chemical; Models, Molecular; Photochemical Processes; Purines; Quantum Theory; Structure-Activity Relationship; Synchrotrons

2009
Base-Pairing Properties of Double-Headed Nucleotides.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2019, May-28, Volume: 25, Issue:30

    Topics: 2-Aminopurine; Adenine; Base Pair Mismatch; Base Pairing; Cytosine; DNA; Guanine; Hypoxanthine; Models, Molecular; Nucleic Acid Conformation; Nucleotides; Thymine

2019
Effect of mutations on binding of ligands to guanine riboswitch probed by free energy perturbation and molecular dynamics simulations.
    Nucleic acids research, 2019, 07-26, Volume: 47, Issue:13

    Topics: 2-Aminopurine; Bacillus subtilis; Bacterial Proteins; Gene Expression Regulation, Bacterial; Guanine; Hypoxanthine; Ligands; Membrane Transport Proteins; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Point Mutation; Riboswitch; Structure-Activity Relationship; Thermodynamics

2019